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Distribution of lymecycline in interstitial fluid and paranasal sinus mucosa. An experimental and clinical study

  • S. E. Holm (a1), A-M. Bergholm (a1), C. Ekedahl (a2) and K. Lundin (a3)



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Chisholm, G. D., Waterworth, P. M., Calnan, J. S. and Garrard, L. P. (1973) Concentration of antibacterial agents in interstitial tissue fluid. British Medical Journal 1: 569573.
Craig, W. A. and Suh, B. (1978) Theory and Practical impact of binding of antimicrobials to serum proteins and tissue. Scandinavian Journal of Infectious Diseases, Supplement 14: 9299.
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Ekedahi, C., Holm, S. E., Jeppson, P.-H., Lindström, J., Ludwig, C. and Bergholm, A.-M. (1981a) Concentration of Phenoxymethyl penicillin (PcV) in the mucous membrane of maxillary sinus in patients with and without signs of sinusitis. Acta Otolaryngologica, 92: 371377.
Ekedahl, C., Holm, S. E., Jeppson, P.-H., Lindström, J., Ludwig, C. and Berholm, A.-M. (1981b) Active phenoxymethyl penicillin in the mucous membranes of the oral bucca and maxillary sinus and in implanted diffusion chambers in rabbits. Acta Otolaryngologica, 92: 151155.
Holm, S. E., Ekedahl, C. and Bergholm, A.-M. (1978) Comparison of antibiotic assays using different experimental models and their possible clinical significance. Scandinavian Journal of Infectious Diseases, Supplement 14: 214220.
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Lundberg, Ch., Malmborg, A.-S. and Ivemark, B. I. (1974) Antibiotic concentrations in relation to structural changes in maxillary sinus mucosa following intramuscular or peroral treatment. Scandinavian Journal of Infectious Diseases, 6: 187.
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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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