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    Kang, Hyun Mi Kim, Ji Young Choi, Eun Hwa Lee, Hoan Jong Yun, Ki Wook and Lee, Hyunju 2016. Clinical Characteristics of Severe Histiocytic Necrotizing Lymphadenitis (Kikuchi-Fujimoto Disease) in Children. The Journal of Pediatrics, Vol. 171, p. 208.

    Magutová, J. 2016. Kikuchi-Fujimoto-Lymphadenitis bei 29-jähriger Patientin. Der Internist, Vol. 57, Issue. 1, p. 90.

    Feder, Henry M. Liu, Jinli and Rezuke, William N. 2014. Kikuchi Disease in Connecticut. The Journal of Pediatrics, Vol. 164, Issue. 1, p. 196.

    Khishfe, Basem F. Krass, Laurie M. and Nordquist, Erik K. 2014. Kikuchi disease presenting with aseptic meningitis. The American Journal of Emergency Medicine, Vol. 32, Issue. 10, p. 1298.e1.

    Lamzaf, L. Harmouche, H. Maamar, M. Adnaoui, M. Aouni, M. and Tazi Mezalek, Z. 2014. Maladie de Kikuchi-Fujimoto : à propos de quatre cas et revue de littérature. Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Vol. 131, Issue. 6, p. 317.

    Lamzaf, L. Harmouche, H. Maamar, M. Adnaoui, M. Aouni, M. and Tazi Mezalek, Z. 2014. Kikuchi-Fujimoto disease: Report of 4 cases and review of the literature. European Annals of Otorhinolaryngology, Head and Neck Diseases, Vol. 131, Issue. 6, p. 329.

    Astudillo, L. 2010. La maladie de Kikuchi-Fujimoto. La Revue de Médecine Interne, Vol. 31, Issue. 11, p. 757.

    Kim, Won-Yong Lee, Seung-Beom Choi, Jun-Jeong and Kang, Hee-Cheol 2010. A Case Report of Kikuchi-Fujimoto Disease with Immune Thrombocytopenic Purpura. Korean Journal of Family Medicine, Vol. 31, Issue. 1, p. 51.

    Park, Se Jin Moon, Won Jin Kim, Wan Seop and Kim, Kyo Sun 2009. Kikuchi-Fujimoto disease with aseptic meningitis. Korean Journal of Pediatrics, Vol. 52, Issue. 5, p. 622.

    Atwater, Amber Reck Longley, B. Jack and Aughenbaugh, William D. 2008. Kikuchi's disease: Case report and systematic review of cutaneous and histopathologic presentations. Journal of the American Academy of Dermatology, Vol. 59, Issue. 1, p. 130.

    Frikha, F. Marzouk, S. Frigui, M. Jallouli, M. Kechaou, M. Kaddour, N. Boudawara, T. Jlidi, R. and Bahloul, Z. 2008. Maladie de Kikuchi-Fujimoto et connectivite : à propos de trois observations. La Revue de Médecine Interne, Vol. 29, Issue. 2, p. 129.

    Glaser, Marjana Borin, Peter Kavalar, Rajko and Skalicky, Marjan 2008. Necrotizing cervical lymphadenopathy: Kikuchi-Fujimoto disease in a young male. Wiener klinische Wochenschrift, Vol. 120, Issue. 11-12, p. 360.

    Lee, Seung Eun Ahn, Jihyun Kim, Jaetaek Oh, Yeon Sahng and Chung, Yun Jae 2008. A Case of Methimazole-induced Agranulocytosis and Kikuchi's Disease in a Patient with Graves' Disease. Journal of Korean Endocrine Society, Vol. 23, Issue. 6, p. 420.

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    Park, Hyun Seok Sung, Min Jung Park, Su Eun and Lim, Young Tak 2007. Kikuchi-Fujimoto disease of 16 children in a single center of Korea. Pediatric Allergy and Immunology, Vol. 18, Issue. 2, p. 174.

    Viallard, Jean-François Parrens, Marie Lazaro, Estibaliz Caubet, Olivier and Pellegrin, Jean-Luc 2007. Lymphadénite histiocytaire nécrosante ou maladie de Kikuchi-Fujimoto. La Presse Médicale, Vol. 36, Issue. 11, p. 1683.

    Altuntas, Fevzi Sari, Ismail Canoz, Ozlem Yildiz, Orhan Eser, Bulent Cetin, Mustafa and Unal, Ali 2006. Kikuchi–Fujimoto disease: a rare but important cause of fever and lymphadenopathy in pregnant women. American Journal of Hematology, Vol. 81, Issue. 2, p. 118.

    Bagg, Andrew Edwards, Charles Altus, Philip and Afanador, Maria 2006. Kikuchi-Fujimoto Disease Masquerading as a Complication From a Periodontal Abscess. Infectious Diseases in Clinical Practice, Vol. 14, Issue. 2, p. 114.

    Gerritsen, Annemieke Lam, King Marion Schneider, E. and van den Heuvel-Eibrink, Marry M. 2006. An exclusive case of juvenile myelomonocytic leukemia in association with Kikuchi's disease and hemophagocytic lymphohistiocytosis and a review of the literature. Leukemia Research, Vol. 30, Issue. 10, p. 1299.

    Kim, Hyun A Chung, Ju-Young Kim, Sang Woo Lim, Sung Jig and Shin, Haeng Seop 2006. Histiocytic necrotizing lymphadenitis in children : association of human herpes virus 8 and Epstein Barr virus. Korean Journal of Pediatrics, Vol. 49, Issue. 8, p. 875.


Management of Kikuchi’s disease using glucocorticoid

  • Yong Ju Jang (a1), Keun Hwan Park (a1) and Hyun Jung Seok (a1)
  • DOI:
  • Published online: 08 March 2006

Histiocytic necrotizing lymphadenitis, or Kikuchi’s disease, is a self-limiting cervical lymphadenitis of unknown origin. Since no specific treatment has been reported for Kikuchi’s disease to date, once a diagnosis of Kikuchi’s disease has been established, the role of the physician has been limited only to treating the symptoms. Sometimes, however, the clinical manifestations of the disease can be very distressing for the patients. Thus, a more aggressive form of treatment may be required for the patients who suffer from severe and persisting symptoms and recurrence. We present three cases of Kikuchi’s disease that benefited significantly from systemic administration of prednisone.

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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
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