Skip to main content
×
×
Home

Lysergic Acid Diethylamide (LSD-25): XXXI. Comparison by questionnaire of psychotomimetic activity of congeners on normal subjects and drug addicts

  • Harold A. Abramson (a1)
Extract

A generally acceptable method of comparing psychotomimetic compounds has apparently not been devised. A method of this type would provide the replicability not now available in the newly developed field of psycho-pharmacology. For example, the method employing the Cold Spring Harbor questionnaire devised by the writer and his co-workers has been criticized as being “too suggestible”, “too structured”, or “insufficiently cognizant of unconscious processing”. It is the purpose of this communication to show that the Cold Spring Harbor questionnaire (1, 2) provides a suitable method of study of the psychotomimetic drugs similar to d-lysergic acid diethylamide (LSD-25). The basis for this statement is the comparison made here of the results of an independent study of a series of congeners of LSD-25 made by Isbell, Miner and Logan (3) in another laboratory, in a different milieu, and on a different population sample. It has been found that the comparative effectiveness of a series of LSD congeners both at Cold Spring Harbor and at Isbell's laboratory in Lexington, Kentucky are the same when the Cold Spring Harbor questionnaire is employed.

Copyright
References
Hide All
1 Abramson, H. A., Jarvik, M. E., Kaufman, M. R., Kornetsky, C., Levine, A., and Wagner, M., “Lysergic Acid Diethylamide (LSD-25): I. Physiological and Perceptual Responses”, J. Psychol, 1955, 39, 3.
2 Idem , “Lysergic Acid Diethylamide (LSD-25): XXX. The Questionnaire Technique with Notes on Its Use”, ibid. In press.
3 Isbell, H., Miner, E. J., and Logan, C. R., “Relationships of Psychotomimetic to Anti-Serotonin Potencies of Congeners of Lysergic Acid Diethylamide (LSD-25)”, Psychopharmacologia, 1959, 1, 20.
4 Abramson, H. A., “Lysergic Acid Diethylamide (LSD-25): XXIX. The Response Index as a Measure of Threshold Activity of Psychotropic Drugs in Man”, J. Psychol, 1959, 48, 65.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

The British Journal of Psychiatry
  • ISSN: 0368-315X
  • EISSN: 2514-9946
  • URL: /core/journals/the-british-journal-of-psychiatry
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed

Lysergic Acid Diethylamide (LSD-25): XXXI. Comparison by questionnaire of psychotomimetic activity of congeners on normal subjects and drug addicts

  • Harold A. Abramson (a1)
Submit a response

eLetters

No eLetters have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *