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The Organic Acids of the Cerebro-Spinal Fluid

  • R. H. Hurst (a1)
Extract

The electrometric titration method for the investigation of “organic acids,” as developed by Perlzweig and Delrue (1) and applied to the examination of sera, indicated a method of investigation of the organic acids of the cerebro-spinal fluid, and an attempt has been made in this paper to investigate the significance of the organic acid titration in mental disorders. Owing to the difficulty of obtaining normal cerebro-spinal fluid, the research had to be confined to the investigation of paretic and non-paretic cerebro-spinal fluids obtained from mental cases. In the former case adequate specimens were obtainable during the process of collection of fluid for diagnostic purposes, and the results obtained in some cases were confirmed by independent collection.

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1 Perlzweig, and Delrue, , Proc. Soc. Exper. Biol. and Med., 1928, xxv, p. 548.
2 Folin, , Journ. Biol. Chem., 1922, li, p. 377.
3 Friedemann, , Cotonio, and Shaffer, , ibid., 1927, lxxiii, p. 335.
4 Clausen, , ibid., 1922, lii, p. 263.
5 Perlzweig, , ibid., xc, No. 2, 1929.
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The British Journal of Psychiatry
  • ISSN: -
  • EISSN: 2514-9946
  • URL: /core/journals/the-british-journal-of-psychiatry
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The Organic Acids of the Cerebro-Spinal Fluid

  • R. H. Hurst (a1)
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