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    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Sims, Jordyn A. Kapse, Kushal Glynn, Peter Sandberg, Chaleece Tripodis, Yorghos and Kiran, Swathi 2016. The relationships between the amount of spared tissue, percent signal change, and accuracy in semantic processing in aphasia. Neuropsychologia, Vol. 84, p. 113.

    Henseler, I. Regenbrecht, F. and Obrig, H. 2014. Lesion correlates of patholinguistic profiles in chronic aphasia: comparisons of syndrome-, modality- and symptom-level assessment. Brain, Vol. 137, Issue. 3, p. 918.

    Daniele, Antonio Barbier, Annalisa Di Giuda, Daniela Vita, Maria Gabriella Piccininni, Chiara Spinelli, Pietro Tondo, Giacomo Fasano, Alfonso Colosimo, Carlo Giordano, Alessandro and Gainotti, Guido 2013. Selective impairment of action-verb naming and comprehension in progressive supranuclear palsy. Cortex, Vol. 49, Issue. 4, p. 948.

  • Journal of the International Neuropsychological Society, Volume 16, Issue 3
  • May 2010, pp. 433-442

When “Crack walnuts” lies in different brain regions: Evidence from a voxel-based lesion-symptom mapping study

  • DOI:
  • Published online: 01 February 2010

Theories of lexical processing differ as to how multimorphemic words, such as compounds, are mentally processed. The most recent findings seem to support the dual route hypothesis, which assumes that complex words can be stored and retrieved either whole or by decomposition into their constituents. Despite great efforts to investigate the cognitive mechanisms involved in processing complex words, very little is known about how compounds are represented in the brain. The present study was designed to address this issue in a group of 20 left-hemispheric stroke patients who were submitted to four picture-naming tasks involving nouns, verbs, noun-noun (NN) and verb-noun (VN) compounds. To determine the brain lesions implicated in these tasks, we analyzed patients’ performances together with their lesions using Voxel-based Lesion Symptom Mapping (VLSM). Results showed that while NN involved the same temporal areas as nouns, VN (although they belong to the noun category) involved different fronto-temporal regions. This latter finding is discussed within the view that distinct mechanisms process the different constituents of complex words. (JINS, 2010, 16, 433–442.)

Corresponding author
*Correspondence and reprint requests to: Prof. Paola Marangolo, Dipartimento di Neuroscienze, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italia. E-mail:
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Journal of the International Neuropsychological Society
  • ISSN: 1355-6177
  • EISSN: 1469-7661
  • URL: /core/journals/journal-of-the-international-neuropsychological-society
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