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Rapid High-resolution Brain Mapping with CLARITY Optimized Light Sheet Microscopy (COLM)

  • Raju Tomer (a1) (a2) and Karl Deisseroth (a1) (a3) (a4) (a2)
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Abstract

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References

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[1] Bock, DD, et al., Nature 471 (2011) 177182.
[2] Briggman, KL, Helmstaedter, M & Denk, W, Nature 471 (2011) 183188.
[3] Dodt, HU, et al., Nat. Methods 4 (2007) 331336.
[4] Hama, H, et al., Nat. Neuroscience 14 (2011) 14811488.
[5] Chung, K, et al., Nature 497 (2013) 332337.
[6] Tomer, R, et al., Nature protocols 9 (2014) 16821697.
[7] Siedentopf, H & Zsigmondy, R, Annalen der Physik 10 (1903) 139.
[8] Huisken, J & Stainier, DY, Development 136 (2009) 19631975.
[9] We thank the entire Deisseroth lab for helpful discussions. All the tools and methods described are distributed and supported freely (clarityresourcecenter.org/COLM.html).

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