Skip to main content
×
Home
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 12
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Wu, J. Guo, W. Wang, C. Li, Y. Chen, T. and Yu, K. 2015. Improving performances of microchannels in microfluidic chip using solidifiable adhesive film. Surface Engineering, Vol. 31, Issue. 7, p. 545.


    Chen, Feng and de Aldana, J. R. Vázquez 2014. Optical waveguides in crystalline dielectric materials produced by femtosecond-laser micromachining. Laser & Photonics Reviews, Vol. 8, Issue. 2, p. 251.


    del Rosal, B. Sun, C. Yan, Y. Mackenzie, M.D. Lu, C. Bettiol, A. A. Kar, A.K. and Jaque, D. 2014. Flow effects in the laser-induced thermal loading of optical traps and optofluidic devices. Optics Express, Vol. 22, Issue. 20, p. 23938.


    He, Fei Liao, Yang Lin, Jintian Song, Jiangxin Qiao, Lingling Cheng, Ya and Sugioka, Koji 2014. Femtosecond Laser Fabrication of Monolithically Integrated Microfluidic Sensors in Glass. Sensors, Vol. 14, Issue. 10, p. 19402.


    Sugioka, Koji Xu, Jian Wu, Dong Hanada, Yasutaka Wang, Zhongke Cheng, Ya and Midorikawa, Katsumi 2014. Femtosecond laser 3D micromachining: a powerful tool for the fabrication of microfluidic, optofluidic, and electrofluidic devices based on glass. Lab on a Chip, Vol. 14, Issue. 18, p. 3447.


    Riken, Koji Sugioka 2013. 2013 Conference on Lasers and Electro-Optics Pacific Rim (CLEOPR). p. 1.

    Shen, Zhenhua Zou, Yun and Chen, Xianfeng 2013. An integrated microfluidic signal generator using multiphase droplet grating. Microfluidics and Nanofluidics, Vol. 14, Issue. 5, p. 809.


    Sugioka, Koji Wu, Dong Midorikawa, Katsumi Bellouard, Y. and Canioni, L. 2013. Ship-in-a-Bottle Biomicrochips Fabricated by Hybrid Femtosecond Laser Processing. MATEC Web of Conferences, Vol. 8, p. 05005.


    Bellini, Nicola Bragheri, Francesca Cristiani, Ilaria Guck, Jochen Osellame, Roberto and Whyte, Graeme 2012. Validation and perspectives of a femtosecond laser fabricated monolithic optical stretcher. Biomedical Optics Express, Vol. 3, Issue. 10, p. 2658.


    Lin, Jintian Yu, Shangjie Ma, Yaoguang Fang, Wei He, Fei Qiao, Lingling Tong, Limin Cheng, Ya and Xu, Zhizhan 2012. On-chip three-dimensional high-Q microcavities fabricated by femtosecond laser direct writing. Optics Express, Vol. 20, Issue. 9, p. 10212.


    Schaap, Allison Rohrlack, Thomas and Bellouard, Yves 2012. Lab on a chip technologies for algae detection: a review. Journal of Biophotonics, Vol. 5, Issue. 8-9, p. 661.


    Sugioka, Koji and Cheng, Ya 2012. Femtosecond laser processing for optofluidic fabrication. Lab on a Chip, Vol. 12, Issue. 19, p. 3576.


    ×

Integrated microchips for biological analysis fabricated by femtosecond laser direct writing

  • Koji Sugioka (a1) and Ya Cheng (a2)
  • DOI: http://dx.doi.org/10.1557/mrs.2011.274
  • Published online: 14 December 2011
Abstract
Abstract

Microchips have revolutionized biological analysis since they can be used to perform biochemical analysis with high efficiency and accuracy. Femtosecond laser direct writing followed by wet chemical etching can be used to fabricate hollow microstructures with almost any three-dimensional (3D) structure without stacking or bonding. This permits microfluidic systems to be integrated with micro-optical components (e.g., mirrors and lenses) and micromechanical components (e.g., valves and pumps) in a glass chip by a single continuous process. Furthermore, other micro-optical components such as optical waveguides and attenuators can be integrated by additional femtosecond laser direct writing. Thus, femtosecond laser direct writing can be used to fabricate functional microfluidics, optofluidics, lab-on-a-chip devices, and micro-total analysis systems. In this study, 3D femtosecond laser micromachining is used to fabricate microchips integrated with functional microcomponents for biological analysis. Optofluidic systems, in which microfluidic components are integrated with micro-optical components, are used to detect single cells and perform high-sensitivity analysis of liquid samples by optical methods. Another interesting microchip is introduced, namely nanoaquariums, which is used for performing dynamic observations of microorganisms and bacteria and allows the functions of microorganisms and bacteria to be determined, such as elucidation of the gliding mechanism of Phormidium to seedling roots for growth acceleration of vegetables.

Copyright
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1.M.A. Burns , B.N. Johnson , A.N. Brahmasandra , K. Handique , J.R. Webster , M. Krishnan , T.S. Sammarco , P.M. Man , D. Jones , D. Heldsinger , C.H. Mastrangelo , D.T. Burke , Science 282, 484 (1998).

2.P.S. Dittrich , K. Tachikawa , A. Manz , Anal. Chem. 78, 3887 (2006).

3.J.C. McDonald , G.M. Whitesides , Acc. Chem. Res. 35, 491 (2002).

4.K.M. Davis , K. Miura , N. Sugiomto , K. Hirao , Opt. Lett. 21, 1729 (1996).

5.A. Marcinkevicius , S. Juodkazis , M. Watanabe , M. Miwa , S. Matsuo , H. Misawa , J. Nishii , Opt. Lett. 26, 277 (2001).

9.S. Matsuo , S. Kiyama , Y. Shichijo , T. Tomita , S. Hashimoto , Y. Hosokawa , H. Masuhara , Appl. Phys. Lett. 93, 051107 (2008).

10.Y. Cheng , K. Sugioka , K. Midorikawa , M. Masuda , K. Toyoda , M. Kawachi , K. Shihoyama , Opt. Lett. 28, 1144 (2003).

13.K. Yamada , W. Watanabe , T. Toma , K. Itoh , J. Nishii , Opt. Lett. 26, 19 (2001).

14.C.B. Scaffer , A. Brodeur , J.F. Garcia , E. Mazur , Opt. Lett. 26, 93 (2001).

15.E. Bricchi , J.D. Mills , P.G. Kazamsky , B.G. Klappauf , J.J. Baumberg , Opt. Lett. 27, 2200 (2002).

16.K. Kawamura , M. Hirano , T. Kamiya , H. Hosono , Appl. Phys. Lett. 81, 1137 (2002).

17.W. Watanabe , D. Kuroda , K. Itoh , J. Nishii , Opt. Express 10, 978 (2002).

19.W. Watanabe , T. Asano , K. Yamada , K. Itoh , J. Nishii , Opt. Lett. 28, 2491 (2003).

21.Y. Hanada , K. Sugioka , H. Kawano , I.S. Ishikawa , A. Miyawaki , K. Midorikawa , Biomed. Microdevices 10, 403 (2008).

22.Y. Hanada , K. Sugioka , I.S. Ishikawa , H. Kawano , A. Miyawaki , K. Midorikawa , Lab Chip 11, 2109 (2011).

23.A. Crespi , Y. Gu , B. Ngamsom , H.J.W.M. Hoekstra , C. Dongre , M. Pollnau , R. Ramponi , H.H. van den Vlekkert , P. Watts , G. Cerullo , R. Osellame , Lab Chip 10, 1167 (2010).

24.M. Kim , D.J. Hwang , H. Jeon , K. Hiromatsu , C.P. Grigoropoulos , Lab Chip 9, 311 (2009).

25.F. Bragheri , L. Ferrara , N. Bellini , K.C. Vishnubhatla , P. Minzioni , R. Ramponi , R. Osellame , I. Cristiani , J. Biophoton. 3, 234 (2010).

26.A. Schaap , Y. Bellouard , T. Rohrlack , Biomed. Opt. Express 2, 658 (2011).

27.Y. Kondo , J.R. Qiu , T. Mitsuyu , K. Hirao , T. Yoko , J. Jpn. Appl. Phys. 38, L1145 (1999).

28.S.D. Stookey , Ind. Eng. Chem. 45, 115 (1953).

30.T. Hongo , K. Sugioka , H. Niino , Y. Cheng , M. Masuda , I. Miyamoto , H. Takai , K. Midorikawa , J. Appl. Phys. 97, 063517 (2005).

32.B. Fisette , F. Busque , J.Y. Degorce , M. Meunier , Appl. Phys. Lett. 88, 091104 (2006).

34.S.M. Eaton , H. Zhang , P.R. Herman , F. Yoshino , L. Shah , K.J. Bovatse , A.Y. Arai , Opt. Express 13, 4708 (2005).

35.J.A. Dharmadhikari , A.K. Dharmadhikari , A. Bhatnagar , A. Mallik , P.C. Singh , R.K. Dhaman , D. Mathur , Opt. Commun. 284, 630 (2011).

36.H. Zhang , S.M. Eaton , P.R. Herman , Opt. Express 14, 4826 (2006).

38.R. Osellame , V. Maselli , R.M. Vazquez , R. Ramponi , G. Cerullo , Appl. Phys. Lett. 90, 231118 (2007).

39.R.M. Vazquez , R. Osellame , D. Nolli , C. Dongre , H. van den Vlekkert , R. Ramponi , M. Pollnau , G. Cerullo , Lab Chip 9, 91 (2009).

40.R.W. Applegate , J. Squier , T. Vestad , J. Oakey , D.W.M. Marr , P. Bado , M.A. Dugan , A.A. Said , Lab Chip 6, 422 (2006).

42.K. Sugioka , Y. Hanada , K. Midorikawa , Laser Photonics Rev. 4, 386 (2010).

43.C. Yamahata , C. Vandevyver , F. Lacharme , P. Izewska , H. Vogel , R. Freitag , M.A.M. Gijs , Lab Chip 5, 1083 (2005).

44.Y. Choi , M.A. McClain , M.C. LaPlaca , A.B. Frazier , M.G. Allen , Biomed. Microdevices 9, 7 (2007).

45.S. Haeberle , R. Zengerle , Lab Chip 7, 1094 (2007).

46.K. Okano , E. Hunter , N. Fusetani , J. Exp. Zool. 276, 138 (1996).

47.K. Yoshimura , C. Shingyoji , K. Takahashi , Cell Motil. Cytoskeleton 36, 236 (1997).

48.S.L. Fleming , C.L. Rieder , Cell Motil. Cytoskeleton 56, 141 (2003).

49.D.J. Stephens , V.J. Allan , Science 300, 82 (2003).

52.L.N. Halfen , R.W. Castenholz , Nature 225, 1163 (1970).

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

MRS Bulletin
  • ISSN: 0883-7694
  • EISSN: 1938-1425
  • URL: /core/journals/mrs-bulletin
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: