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Size Also Matters in Biodegradable Composite Microfiber Reinforced by Chitosan Nanofibers

Published online by Cambridge University Press:  22 January 2014

Elisabete D. Pinho
Affiliation:
3B’s Research Group – Biomaterials, Biodegradables and Biomimetics. Department of Polymer Engineering, University of Minho; Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine. AvePark, Zona Industrial da Gandra, S. Cláudio do Barco 4806-909 Caldas das Taipas, Guimarães, Portugal. ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal.
Albino Martins
Affiliation:
3B’s Research Group – Biomaterials, Biodegradables and Biomimetics. Department of Polymer Engineering, University of Minho; Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine. AvePark, Zona Industrial da Gandra, S. Cláudio do Barco 4806-909 Caldas das Taipas, Guimarães, Portugal. ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal.
José V. Araújo
Affiliation:
3B’s Research Group – Biomaterials, Biodegradables and Biomimetics. Department of Polymer Engineering, University of Minho; Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine. AvePark, Zona Industrial da Gandra, S. Cláudio do Barco 4806-909 Caldas das Taipas, Guimarães, Portugal. ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal.
Rui L. Reis
Affiliation:
3B’s Research Group – Biomaterials, Biodegradables and Biomimetics. Department of Polymer Engineering, University of Minho; Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine. AvePark, Zona Industrial da Gandra, S. Cláudio do Barco 4806-909 Caldas das Taipas, Guimarães, Portugal. ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal.
Nuno M. Neves
Affiliation:
3B’s Research Group – Biomaterials, Biodegradables and Biomimetics. Department of Polymer Engineering, University of Minho; Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine. AvePark, Zona Industrial da Gandra, S. Cláudio do Barco 4806-909 Caldas das Taipas, Guimarães, Portugal. ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal.
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Abstract

Pioneer works on nanocomposites were focused in carbon nanofibers or nanotubes dispersed in epoxy matrix, a viscous liquid facilitating the compounding stage. The interest in developing new composites aimed for biomedical applications led us to design new nanocomposites based in biodegradable polymers with demonstrated biological performance.

We report herein the development of micro-nano composites by extruding poly(butylene succinate) (PBS) microfibers with two different diameters, 200 and 500 µm, reinforced with electrospun chitosan nanofibers. Analysis of the microfibers showed high levels of alignment of the reinforcing phase and excellent distribution of the nanofibers in the composite. Its geometry facilitates the development of orthotropy, maximizing the reinforcement in the axial fiber main axis.

The biodegradable microfiber composites show an outstanding improvement of mechanical properties and of the kinetics of biodegradation, with very small fractions (0.05 and 0.1 wt.%) of electrospun chitosan nanofibers reinforcement. The high surface area-to-volume ratio of electrospun nanofibers combined with the increased water uptake capability of chitosan justify the accelerated kinetics of biodegradation of the composite as compared with the unfilled synthetic polymer.

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Articles
Copyright
Copyright © Materials Research Society 2014 

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References

REFERENCES

Stodolak, E., Paluszkiewicz, C., Bogun, M. and Blazewicz, M., J. Mol. Struc., 924926, 208 (2009).CrossRef
Soundararajah, Q. Y., Karunaratne, B. S. B. and Rajapakse, R. M. G., Mater. Chem. Phys. 113, 850 (2009).CrossRef
Coleman, J. N., Khan, U. and Gun’ko, Y. K., Adv. Mater. 18, 689 (2006).CrossRef
Pinho, E. D., Martins, A., Araújo, J. V., Reis, R. L. and Neves, N. M., Acta Biomater. 5, 1104 (2009).CrossRef
Liu, L.-Q., Tasis, D., Prato, M. and Wagner, H. D., Adv. Mater. 19, 1228 (2007).CrossRef
Yeo, L. Y. and Friend, J. R., J. Exp. Nanosci. 1, 177 (2006).CrossRef
Huang, Z.-M., Zhang, Y.-Z., Kotaki, M. and Ramakrishna, S., Compos. Sci. Technol. 63, 2223 (2003).CrossRef
Venugopal, J., Vadgama, P., Kumar, T. S. S. and Ramakrishna, S., Nanotechnology 18, 511 (2007).CrossRef
Martins, A., Reis, R. L. and Neves, N. M., Int. Mater. Rev. 53, 257 (2008).CrossRef
Lin, T., Wang, H. and Wang, X.. Adv. Mater. 17, 2699 (2005).CrossRef
Martins, A., Pinho, E. D., Faria, S., Pashkuleva, I., Marques, A. P., Reis, R. L. and Neves, N. M., Small 5, 1195 (2009).
Correlo, V. M., Boesel, L. F., Bhattacharya, M., Mano, J. F., Neves, N. M. and Reis, R. L., Macrom. Mater. Eng. 290, 1157 (2005).CrossRef
Correlo, V. M., Pinho, E. D., Pashkuleva, I., Bhattacharya, M., Neves, N. M. and Reis, R. L., Macromol. Biosci. 7, 354 (2007).CrossRef
Costa-Pinto, A. R., Salgado, A. J., Correlo, V. M., Sol, P. C., Bhattacharya, M., Charbord, P., Reis, R. L. and Neves, N. M., Tissue Eng. Part A 14, 1049 (2008).CrossRef
Oliveira, J. T., Correlo, V. M., Sol, P. C., Costa-Pinto, A. R., Malafaya, P. B., Salgado, A. J., Bhattacharya, M., Charbord, P., Neves, N. M. and Reis, R. L., Tissue Eng. Part A 14, 1651 (2008).CrossRef
Coutinho, D. F., Pashkuleva, I., Alves, C. M., Marques, A. P., Neves, N. M. and Reis, R. L., Biomacromolecules 9,1139 (2008).CrossRef
Van Krevelen, D. W. Properties of polymers. 3 rd Ed. Amsterdam. Elsevier, 1990.Google Scholar
Neves, N. M., Isdell, G., Pouzada, A. S. and Powell, P. C., Polym. Compos. 19, 640 (1998).CrossRef
Mahfuz, H., Adnan, A., Rangari, V. K., Jeelani, S. and Jang, B. Z., Composites: Part A 35, 519 (2004).CrossRef
Krause, W., Henning, F., Tröster, S., Geiger, O. and Eyerer, P., J. Thermoplas. Compo. Mater. 16, 289 (2003).CrossRef
Correlo, V. M., Boesel, L. F., Bhattacharya, M., Mano, J. F., Neves, N. M. and Reis, R. L., Mater. Sci. Eng. A 403, 57 (2005).CrossRef
Pavlov, M. P., Mano, J. F., Neves, N. M. and Reis, R. L., Macromol. Biosci. 4, 776 (2004).CrossRef

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Size Also Matters in Biodegradable Composite Microfiber Reinforced by Chitosan Nanofibers
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