This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.
Y. Arsenijevic , J.G. Villemure , J.F. Brunet , J.J. Bloch , N. Deglon , C. Kostic (2001) Isolation of multipotent neural precursors residing in the cortex of the adult human brain. Experimental Neurology 170, 48–62.
S. Belachew , R. Chittajallu , A.A. Aguirre , X. Yuan , M. Kirby , S. Anderson (2003) Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons. Journal of Cell Biology 161, 169–186.
T. Ben-Hur and S.A. Goldman (2008) Prospects of cell therapy for disorders of myelin. Annals of the New York Academy of Sciences 1142, 218–249.
J. Bradbury (2002) Time right for statin trials in multiple sclerosis. Lancet 360, 1483.
J.D. Cahoy , B. Emery , A. Kaushal , L.C. Foo , J.L. Zamanian , K.S. Christopherson (2008) A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. Journal of Neuroscience 28, 264–278.
L. Dimou , C. Simon , F. Kirchhoff , H. Takebayashi and M. Gotz (2008) Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex. Journal of Neuroscience 28, 10434–10442.
C. ffrench-Constant and M.C. Raff (1986) Proliferating bipotential glial progenitor cells in adult rat optic nerve. Nature 319, 499–502.
R.J. Franklin (2002) Why does remyelination fail in multiple sclerosis? Nature Reviews. Neuroscience 3, 705–714.
F.H. Gage (2000) Mammalian neural stem cells. Science 287, 1433–1438.
S.A. Goldman , S. Schanz and M.S. Windrem (2008) Stem cell-based strategies for treating pediatric disorders of myelin. Human Molecular Genetics 17, R76–R83.
R.E. Gross , M.F. Mehler , P.C. Mabie , Z. Zang , L. Santschi and J.A. Kessler (1996) Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells. Neuron 17, 595–606.
P. He and Y. Shen (2009) Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. Journal of Neuroscience 29, 6545–6557.
B.Y. Hu , Z.W. Du , X.J. Li , M. Ayala and S.C. Zhang (2009) Human oligodendrocytes from embryonic stem cells: conserved SHH signaling networks and divergent FGF effects. Development 136, 1443–1452.
I. Inoue , S. Goto , K. Mizotani , T. Awata , T. Mastunaga , S. Kawai (2000) Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in primary endothelial cells. Life Science 67, 863–876.
R.A. Irizarry , B.M. Bolstad , F. Collin , L.M. Cope , B. Hobbs and T.P. Speed (2003) Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Research 31, e15.
H.M. Keyoung and S.A. Goldman (2007) Glial progenitor cell-based repair of demyelinating neurological diseases. Neurosurgery Clinics of North America 18, 93–104.
S.Y. Kim and D.J. Volsky (2005) PAGE: parametric analysis of gene set enrichment. BMC Bioinformatics 6, 144.
B. Kirschenbaum , M. Nedergaard , A. Preuss , K. Barami , R.A. Fraser and S.A. Goldman (1994) In vitro neuronal production and differentiation by precursor cells derived from the adult human forebrain. Cerebral Cortex 4, 576–589.
S. Klopfleisch , D. Merkler , M. Schmitz , S. Kloppner , M. Schedensack , G. Jeserich (2008) Negative impact of statins on oligodendrocytes and myelin formation in vitro and in vivo. Journal of Neuroscience 28, 13609–13614.
T. Kondo and M. Raff (2000) Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells. Science 289, 1754–1757.
D.A. Lim , A.D. Tramontin , J.M. Trevejo , D.G. Herrera , J.M. Garcia-Verdugo and A. Alvarez-Buylla (2000) Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron 28, 713–726.
K. Meng , A. Rodriguez-Pena , T. Dimitrov , W. Chen , M. Yamin , M. Noda (2000) Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta. Proceedings of the National Academy of Sciences of the U.S.A. 97, 2603–2608.
V. Miron , S. Rajasekharan , A. Jarjour , S. Zamvil , T. Kennedy and J. Antel (2007) Simvastatin regulates oligodendroglial process dynamics and survival. Glia 55, 130–143.
V.E. Miron , S.P. Zehntner , T. Kuhlmann , S.K. Ludwin , T. Owens , T.E. Kennedy (2009) Statin therapy inhibits remyelination in the central nervous system. American Journal of Pathology 174, 1880–1890.
M. Noble , D. Wren and G. Wolswijk (1992) The O-2A(adult) progenitor cell: a glial stem cell of the adult central nervous system. Seminars in Cell Biology 3, 413–422.
M.C. Nunes , N.S. Roy , H.M. Keyoung , R.R. Goodman , G. McKhann , L. Jiang (2003) Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain. Nature Medicine 9, 439–447.
N. Oberheim , X. Wang , S. Goldman and S.A. Nedergaard (2006) Astrocytic complexity distinguishes the human brain. Trends in Neurosciences 29, 1–10.
N.A. Oberheim , T. Takano , X. Han , W. He , J.H. Lin , F. Wang (2009) Uniquely hominid features of adult human astrocytes. Journal of Neuroscience 29, 3276–3287.
M.C. Raff , R.H. Miller and M. Noble (1983) A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature 303, 390–396.
R.B. Rawson (2003) The SREBP pathway – insights from insigs and insects. Nature Reviews. Molecular Cell Biology 4, 631–640.
L.E. Rivers , K.M. Young , M. Rizzi , F. Jamen , K. Psachoulia , A. Wade (2008) PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Nature Neuroscience 11, 1392–1401.
I. Saluja , J.G. Granneman and R.P. Skoff (2001) PPAR delta agonists stimulate oligodendrocyte differentiation in tissue culture. Glia 33, 191–204.
N. Scolding , R. Franklin , S. Stevens , C.H. Heldin , A. Compston and J. Newcombe (1998) Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis. Brain 121, 2221–2228.
S. Shen , A. Liu , J. Li , C. Wolubah and P. Casaccia-Bonnefil (2008a) Epigenetic memory loss in aging oligodendrocytes in the corpus callosum. Neurobiology of Aging 29, 452–463.
S. Shen , J. Sandoval , V.A. Swiss , J. Li , J. Dupree , R.J. Franklin (2008b) Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nature Neuroscience 11, 1024–1034.
F.J. Sim and S.A. Goldman (2005) White matter progenitor cells reside in an oligodendrogenic niche. Ernst Schering Research Foundation Workshop 53, 61–81.
F.J. Sim , J.K. Lang , T.A. Ali , N.S. Roy , G.E. Vates , W.H. Pilcher (2008) Statin treatment of adult human glial progenitors induces PPAR gamma-mediated oligodendrocytic differentiation. Glia 56, 954–962.
F.J. Sim , J.K. Lang , B. Waldau , N.S. Roy , T.E. Schwartz , W.H. Pilcher (2006) Complementary patterns of gene expression by human oligodendrocyte progenitors and their environment predict determinants of progenitor maintenance and differentiation. Annals of Neurology 59, 763–779.
G.K. Smyth (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Statistical Applications in Genetics and Molecular Biology 3, Article3, PMID: 16646809.
R. Stanislaus , K. Pahan , A.K. Singh and I. Singh (1999) Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin. Neuroscience Letters 269, 71–74.
W. Talloen , D.A. Clevert , S. Hochreiter , D. Amaratunga , L. Bijnens , S. Kass (2007) I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data. Bioinformatics 23, 2897–2902.
S. Temple and M.C. Raff (1985) Differentiation of a bipotential glial progenitor cell in a single cell microculture. Nature 313, 223–225.
T. Vollmer , L. Key , V. Durkalski , W. Tyor , J. Corboy , S. Markovic-Plese (2004) Oral simvastatin treatment in relapsing-remitting multiple sclerosis. Lancet 363, 1607–1608.
M. Weber , T. Prod'homme , L. Steinman and L. Zamvil (2005) Drug insight: using statins to treat neuroinflammatory disease. Nature Clinical Practice. Neurology 1, 106–112.
M.S. Windrem , M.C. Nunes , W.K. Rashbaum , T.H. Schwartz , R.A. Goodman , G. McKhann (2004) Fetal and adult human oligodendrocyte progenitor cell isolates myelinate the congenitally dysmyelinated brain. Nature Medicine 10, 93–97.
M.S. Windrem , N.S. Roy , J. Wang , M. Nunes , A. Benraiss , R. Goodman (2002) Progenitor cells derived from the adult human subcortical white matter disperse and differentiate as oligodendrocytes within demyelinated lesions of the rat brain. Journal of Neuroscience Research 69, 966–975.
M.S. Windrem , S. Schanz , M. Guo , G.-F. Tian , V. Washco , N. Stanwood (2008) Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwsie lethally hypomyelinated shiverer mouse. Cell Stem Cell 2, 553–565.
T. Yamashima , A.B. Tonchev , I.H. Vachkov , B.K. Popivanova , T. Seki , K. Sawamoto (2004) Vascular adventitia generates neuronal progenitors in the monkey hippocampus after ischemia. Hippocampus 14, 861.
S.C. Zhang , B. Ge and I.D. Duncan (1999) Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity. Proceedings of the National Academy of Sciences of the U.S.A. 96, 4089–4094.
X. Zhu , D.E. Bergles and A. Nishiyama (2008) NG2 cells generate both oligodendrocytes and gray matter astrocytes. Development 135, 145–157.
S. Goldman (2003) Glia as neural progenitor cells. Trends in Neuroscience 26, 590–596.
A. Subramanian , P. Tamayo , V.K. Mootha , S. Mukherjee , B.L. Ebert , M.A. Gillette (2005) Gene set enrichment analysis: A knowledge based approach for interpreting genome-wide expression profiles. Proceedings of the National Academy of Sciences of the U.S.A. 102, 15545–15550.