Skip to main content
×
Home
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 56
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Boissier, Jérôme Grech-Angelini, Sébastien Webster, Bonnie L Allienne, Jean-François Huyse, Tine Mas-Coma, Santiago Toulza, Eve Barré-Cardi, Hélène Rollinson, David Kincaid-Smith, Julien Oleaga, Ana Galinier, Richard Foata, Joséphine Rognon, Anne Berry, Antoine Mouahid, Gabriel Henneron, Rémy Moné, Hélène Noel, Harold and Mitta, Guillaume 2016. Outbreak of urogenital schistosomiasis in Corsica (France): an epidemiological case study. The Lancet Infectious Diseases, Vol. 16, Issue. 8, p. 971.


    Hammad, A. Nouri, Manahil Alfadil, Abdelbagi Musa, H. A. Osman, M. A. Bashir, A. E. Omer, Nawal Hassan, Yasir Alfarazdeg, A. and Mustafa, A. 2016. Detection and Quantification of Anti-Inflammatory Cytokine in Sera and Urine of Sudanese Patients Infected with <i>Schistosoma haematobium</i>. Open Journal of Medical Microbiology, Vol. 06, Issue. 01, p. 32.


    Nor, Bahiyah Young, Neil D. Korhonen, Pasi K. Hall, Ross S. Tan, Patrick Lonie, Andrew and Gasser, Robin B. 2016. Pipeline for the identification and classification of ion channels in parasitic flatworms. Parasites & Vectors, Vol. 9, Issue. 1,


    Abd El-Aal, Amany A Bayoumy, Ibrahim R Basyoni, Maha M A Abd El-Aal, Asmaa A Emran, Ashraf M Abd El-Tawab, Magda S Badawi, Manal A Zalat, Rabab M and Diab, Tarek M 2015. Genomic instability in complicated and uncomplicated Egyptian schistosomiasis haematobium patients. Molecular Cytogenetics, Vol. 8, Issue. 1, p. 1.


    Aemero, Mulugeta Boissier, Jérôme Climent, Deborah Moné, Hélène Mouahid, Gabriel Berhe, Nega and Erko, Berhanu 2015. Genetic diversity, multiplicity of infection and population structure of Schistosoma mansoni isolates from human hosts in Ethiopia. BMC Genetics, Vol. 16, Issue. 1,


    Breugelmans, Bert Ansell, Brendan R. E. Young, Neil D. Amani, Parisa Stroehlein, Andreas J. Sternberg, Paul W. Jex, Aaron R. Boag, Peter R. Hofmann, Andreas and Gasser, Robin B. 2015. Flatworms have lost the right open reading frame kinase 3 gene during evolution. Scientific Reports, Vol. 5, p. 9417.


    Grimes, Jack ET Croll, David Harrison, Wendy E Utzinger, Jürg Freeman, Matthew C and Templeton, Michael R 2015. The roles of water, sanitation and hygiene in reducing schistosomiasis: a review. Parasites & Vectors, Vol. 8, Issue. 1,


    Hagen, Jana Scheerlinck, Jean-Pierre Y. and Gasser, Robin B. 2015. Knocking down schistosomes – promise for lentiviral transduction in parasites. Trends in Parasitology, Vol. 31, Issue. 7, p. 324.


    Le, Thien-Linh Sokolow, Susanne H. Hammam, Olfat Fu, Chi-Ling and Hsieh, Michael 2015. Human Emerging and Re-emerging Infections.


    Le, Thien-Linh P. Boyett, Deborah M. Hurley-Novatny, Amelia and Hsieh, Michael H. 2015. Hamster Weight Patterns Predict the Intensity and Course ofSchistosoma haematobiumInfection. Journal of Parasitology, Vol. 101, Issue. 5, p. 542.


    Ochodo, Eleanor A Gopalakrishna, Gowri Spek, Bea Reitsma, Johannes B van Lieshout, Lisette Polman, Katja Lamberton, Poppy Bossuyt, Patrick MM Leeflang, Mariska MG and Ochodo, Eleanor A 2015. Cochrane Database of Systematic Reviews.


    Price, A. Verma, A. and Welfare, W. 2015. Are health education interventions effective for the control and prevention of urogenital schistosomiasis in sub-Saharan Africa? A systematic review. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 109, Issue. 4, p. 239.


    Rosser, A. Rollinson, D. Forrest, M. and Webster, B L 2015. Isothermal Recombinase Polymerase amplification (RPA) of Schistosoma haematobium DNA and oligochromatographic lateral flow detection. Parasites & Vectors, Vol. 8, Issue. 1,


    Stecher, Chalotte Willemann Kallestrup, Per Kjetland, Eyrun Floerecke Vennervald, Birgitte and Petersen, Eskild 2015. Considering treatment of male genital schistosomiasis as a tool for future HIV prevention: a systematic review. International Journal of Public Health, Vol. 60, Issue. 7, p. 839.


    Stroehlein, Andreas J. Young, Neil D. Jex, Aaron R. Sternberg, Paul W. Tan, Patrick Boag, Peter R. Hofmann, Andreas and Gasser, Robin B. 2015. Defining the Schistosoma haematobium kinome enables the prediction of essential kinases as anti-schistosome drug targets. Scientific Reports, Vol. 5, p. 17759.


    Zepeda, Celenne Morfin and Coffey, Kristen H. 2015. Schistosoma haematobiumInfection That Mimics Bladder Cancer in a 66-Year-Old Ethnic Egyptian Man. Laboratory Medicine, Vol. 46, Issue. 4, p. 338.


    Campos, Tulio D L Young, Neil D Korhonen, Pasi K Hall, Ross S Mangiola, Stefano Lonie, Andrew and Gasser, Robin B 2014. Identification of G protein-coupled receptors in Schistosoma haematobium and S. mansoni by comparative genomics. Parasites & Vectors, Vol. 7, Issue. 1, p. 242.


    Chuah, Candy Jones, Malcolm K. Burke, Melissa L. McManus, Donald P. and Gobert, Geoffrey N. 2014. Cellular and chemokine-mediated regulation in schistosome-induced hepatic pathology. Trends in Parasitology, Vol. 30, Issue. 3, p. 141.


    Hagen, Jana Young, Neil D. Every, Alison L. Pagel, Charles N. Schnoeller, Corinna Scheerlinck, Jean-Pierre Y. Gasser, Robin B. and Kalinna, Bernd H. 2014. Omega-1 knockdown in Schistosoma mansoni eggs by lentivirus transduction reduces granuloma size in vivo. Nature Communications, Vol. 5, p. 5375.


    Lee, Erinna F. Young, Neil D. Lim, Nicholas T.Y. Gasser, Robin B. and Fairlie, W. Douglas 2014. Apoptosis in schistosomes: toward novel targets for the treatment of schistosomiasis. Trends in Parasitology, Vol. 30, Issue. 2, p. 75.


    ×

A wake up call for urinary schistosomiasis: reconciling research effort with public health importance

  • D. ROLLINSON (a1)
  • DOI: http://dx.doi.org/10.1017/S0031182009990552
  • Published online: 23 July 2009
Abstract
SUMMARY

This review considers the current status of urinary schistosomiasis, caused by infection with Schistosoma haematobium, and argues that greater research effort and focus are needed to improve understanding of this neglected tropical disease (NTD). The inappropriateness of relying solely on data concerning the much more extensively studied intestinal form of schistosomiasis caused by S. mansoni is highlighted. The current lack of genome and transcriptome information for S. haematobium is directly hindering further targeted research and must be quickly rectified. Recent molecular phylogenies caution the expectation of similarities between schistosome species and highlight the close relationships of species within the S. haematobium group. Treatment, current and prospective drugs and vaccines, together with diagnosis are considered, highlighting the differences associated with urinary schistosomiasis. This infection has a significant and specific impact on the urino-genital system and has a strong association with bladder cancer, leading to severe and chronic morbidity. There is a clear need for new clinical initiatives in this area to better quantify the disease burden. Furthermore, emerging associations with HIV and other pathogens need to be closely monitored. Research is urgently needed to improve current knowledge in order to develop the next generation of control tools.

Copyright
Corresponding author
*Tel: +44 (0)20 7942 5181. E-mail: D.Rollinson@nhm.ac.uk
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

H. Abol-Enein (2008). Infection: Is it a cause of bladder cancer? Scandinavian Journal of Urology and Nephrology 42 (Suppl. 218), 7984.

A. D. Aragon , R. A. Imani , V. R. Blackburn , P. M. Cupit , S. D. Melman , T. Goronga , T. Webb , E. S. Loker and C. Cunningham (2009). Towards an understanding of the mechanism of action of praziquantel. Molecular and Biochemical Parasitology 164, 5765.

G. Armengol , S. Eissa , J. J. Lozano , S. Shoman , L. Sumoy , M. R. Caballín and S. Knuutila (2007). Genomic imbalances in Schistosoma-associated and non-Schistosoma-associated bladder carcinoma. An array comparative genomic hybridization analysis. Cancer Genetics and Cytogenetics 177, 1619.

B. Ayele , B. Erko , M. Legesse , A. Hailu and G. Medhin (2008). Evaluation of circulating cathodic antigen (CCA) strip for diagnosis of urinary schistosomiasis in Hassoba school children, Afar, Ethiopia. Parasite 15, 6975.

C. I. Balog , P. J. Hensbergen , R. Derks , J. J. Verweij , G. J. van Dam , B. J. Vennervald , A. M. Deelder , and O. A. Mayboroda (2009). Novel automated biomarker discovery work flow for urinary peptidomics. Clinical Chemistry 55, 117–25.

R. S. Barsoum (2003). End-stage renal disease in North Africa. Kidney International Supplement 63, S111S114.

R. Bedwani , E. Renganathan , F. El Kwhsky , C. Braga , H. H. Abu Seif , T. Abul Azm , A. Zaki and C. La Vecchia (1998). Schistosomiasis and the risk of bladder cancer in Alexandria, Egypt. British Journal of Cancer 77, 11861189.

R. Bergquist (2008). A century of schistosomiasis research. Acta Tropica 108, 6568.

K.-H. Bichler , G. Feil , A. Zumbrägel , E. Eipper and S. Dyballa (2001). Schistosomiasis: A critical review. Current Opinion in Urology 11, 97101.

S. Borrmann , N. Szlezák , J.-F. Faucher , P.-B. Matsiegui , R. Neubauer , R. K. Binder , B. Lell and P. G. Kremsner (2001). Artesunate and praziquantel for the treatment of Schistosoma haematobium infections: A double-blind, randomized, placebo-controlled study. Journal of Infectious Diseases 184, 13631366.

K. M. Bosompem , O. Owusu , E. O. Okanla and S. Kojima (2004 b). Applicability of a monoclonal antibody-based dipstick in diagnosis of urinary schistosomiasis in the Central Region of Ghana. Tropical Medicine and International Health 9, 991996.

D. Boulanger , A. Warter , B. Sellin , V. Lindner , R. J. Pierce , J.-P. Chippaux and A. Capron (1999). Vaccine potential of a recombinant glutathione S-transferase cloned from Schistosoma haematobium in primates experimentally infected with an homologous challenge. Vaccine 17, 319326. doi: 10.1016/S0264-410X(98)00202-3.

M. Brown , M. Kizza , C. Watera , M. A. Quigley , S. Rowland , P. Hughes , J. A. G. Whitworth and A. M. Elliott (2004). Helminth infection is not associated with faster progression of HIV disease in coinfected adults in Uganda. Journal of Infectious Diseases 190, 18691879.

C. R. Caffrey (2007). Chemotherapy of schistosomiasis: present and future. Current Opinion in Chemical Biology 11, 433439.

A. Capron , M. Capron and G. Riveau (2002). Vaccine development against schistosomiasis from concepts to clinical trials. British Medical Bulletin 62, 139148.

A. Capron and J.-P. Dessaint (1992). Immunologic aspects of schistosomiasis. Annual Review of Medicine 43, 209218.

A. Capron , G. Riveau , M. Capron and F. Trottein (2005). Schistosomes: The road from host-parasite interactions to vaccines in clinical trials. Trends in Parasitology 21, 143149. doi: 10.1016/j.pt.2005.01.003.

A. C. A. Clements , S. Brooker , U. Nyandindi , A. Fenwick and L. Blair (2008). Bayesian spatial analysis of a national urinary schistosomiasis questionnaire to assist geographic targeting of schistosomiaisis in Tanzania, East Africa. International Journal for Parasitology 38, 401415.

D. G. Colley and W. E. Secor (2007). A schistosomiasis research agenda. PLoS Neglected Tropical Diseases 1, 17.

A. Danso-Appiah , J. Utzinger , J. Liu and P. Olliaro (2008). Drugs for treating urinary schistosomiasis. Cochrane Database of Systematic Reviews (3), art. no. CD000053.

D. De Clercq , J. Vercruysse , A. Kongs , P. Verlé , J. P. Dompnier and P. C. Faye (2002). Efficacy of artesunate and praziquantel in Schistosoma haematobium infected schoolchildren. Acta Tropica 82, 6166.

M. J. Doenhoff and L. Pica-Mattoccia (2006). Praziquantel for the treatment of schistosomiasis: Its use for control in areas with endemic disease and prospects for drug resistance. Expert Review of Anti-Infective Therapy 4, 199210.

M. J. Doenhoff , D. Cioli and J. Utzinger (2008). Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis. Current Opinion in Infectious Diseases 21, 659667.

A. M. Elliott , P. A. Mawa , S. Joseph , P. B. Namujju , M. Kizza , J. S. Nakiyingi , C. Watera and J. A. G. Whitworth (2003). Associations between helminth infection and CD4+ T cell count, viral load and cytokine responses in HIV-1-infected Ugandan adults. Transactions of the Royal Society of Tropical Medicine and Hygiene 97, 103108.

S. El-Mahgoub (1982). Pelvic schistosomiasis and infertility. International Journal of Gynecology and Obstetrics 20, 201206.

D. Engels , L. Chitsulo , A. Montresor , L. Savioli (2002). The global epidemiological situation of schistosomiasis and new approaches to control and research. Acta Tropica 82, 139146.

A. S. Felix , A. S. Soliman , H. Khaled , M. S. Zaghloul , M. Banerjee , M. El-Baradie , M. El-Kalawy and M. L. Wilson (2008). The changing patterns of bladder cancer in Egypt over the past 26 years. Cancer Causes and Control 19, 421429.

A. Fenwick , J. Keiser and J. Utzinger (2006). Epidemiology, burden and control of schistosomiasis with particular consideration to past and current treatment trends. Drugs of the Future 31, 413425.

M. D. French , D. Rollinson , M.-G. Basáñez , A. F. Mgeni , I. S. Khamis , J. R. Stothard (2007). School-based control of urinary schistosomiasis on Zanzibar, Tanzania: Monitoring micro-haematuria with reagent strips as a rapid urological assessment. Journal of Pediatric Urology 3, 364368.

J. F. Friedman , P. Mital , H. K. Kanzaria , G. R. Olds and J. D. Kurtis (2007). Schistosomiasis and pregnancy. Trends in Parasitology 23, 159164.

P. Hagan and O. Sharaf (2003). Schistosomiasis vaccines. Expert Opinion on Biological Therapy 3, 12711278.

P. Hagan , C. C. Appleton , G. C. Coles , J. R. Kusel and L.-A. Tchuem-Tchuenté (2004). Schistosomiasis control: Keep taking the tablets. Trends in Parasitology 20, 9297.

D. A. Hameed , A. M. Abdel Raheem , E. Mosad , H. M. Hammouda , N. A. Kamel and M. A. Abdel Aziz (2008). Bcl-XL and Bcl-2 expression in bilharzial squamous cell carcinoma of the urinary bladder: which protein is prognostic? Urology 72, 374378.

J. V. Hamilton , M. Klinkert and M. J. Doenhoff (1998). Diagnosis of schistosomiasis: Antibody detection, with notes on parasitological and antigen detection methods. Parasitology 117 (Suppl.), S41S57.

H. Hoffmann and I. Bauerfeind (2003). High tissue egg burden mechanically impairing the tubal motility in genital schistosomiasis of the female. Acta Obstetricia et Gynecologica Scandinavica 82, 970971.

M. C. Hosseinipour , S. Napravnik , G. Joaki , S. Gama , N. Mbeye , B. Banda , F. Martinson and M. S. Cohen (2007). HIV and parasitic infection and the effect of treatment among adult outpatients in Malawi. Journal of Infectious Diseases 195, 12781282.

P. C. Inyang-Etoh , G. C. Ejezie , M. F. Useh and E. C. Inyang-Etoh (2009). Efficacy of a combination of praziquantel and artesunate in the treatment of urinary schistosomiasis in Nigeria. Transactions of the Royal Society of Tropical Medicine and Hygiene 103, 3844.

M. Jung , K. Lee , H. Kim and M. Park (2004). Recent advances in artemisinin and its derivatives as antimalarial and antitumor agents. Current Medicinal Chemistry 11, 12651284.

N. B. Kabatereine , B. J. Vennervald , J. H. Ouma , J. Kemijumbi , A. E. Butterworth , D. W. Dunne and A. J. Fulford (1999). Adult resistance to schistosomiasis mansoni: age-dependence of reinfection remains constant in communities with diverse exposure patterns. Parasitology 118, 101105.

P. Kallestrup , R. Zinyama , E. Gomo , A. E. Butterworth , G. J. Van Dam , C. Erikstrup and H. Ullum (2005). Schistosomiasis and HIV-1 infection in rural Zimbabwe: Implications of coinfection for excretion of eggs. Journal of Infectious Diseases 191, 13111320.

R. A. Kane , J. R. Stothard , A. M. Emery and D. Rollinson (2008). Molecular characterization of freshwater snails in the genus Bulinus: a role for barcodes? Parasites and Vectors 1, 15 PMID 18544153.

D. M. S. Karanja , A. W. Hightower , D. G. Colley , P. N. M. Mwinzi , K. Galil , J. Andove and W. E. Secor (2002). Resistance to reinfection with Schistosoma mansoni in occupationally exposed adults and effect of HIV-1 co-infection on susceptibility: a longitudinal study. Lancet 360, 592592.

N. Katz (2008). The discovery of Schistosomiasis mansoni in Brazil. Acta Tropica 108, 6971.

J. Keiser and J. Utzinger (2007). Artemisinins and synthetic trioxolanes in the treatment of helminth infections. Current Opinion in Infectious Diseases 20, 605612.

H. M. Khaled , N. Gad El-Mawla , A. El-Said , M.-R. Hamza , R. Gaafar , I. El-Attar , A. Abu Rabia and I. Magrath (1996). Combination chemotherapy for advanced bilharzial bladder carcinoma. Annals of Oncology 7, 751754.

J. N. Kitinya , P. A. Laurèn , L. J. Eshleman , L. Paljärvi and K. Tanaka (1986). The incidence of squamous and transitional cell carcinomas of the urinary bladder in northern Tanzania in areas of high and low levels of endemic Schistosoma haematobium infection. Transactions of the Royal Society of Tropical Medicine and Hygiene 80, 935939.

E. F. Kjetland , E. N. Kurewa , P. D. Ndhlovu , N. Midzi , L. Gwanzura , P. R. Mason , E. Gomo and S. G. Gundersen (2008 a). Female genital schistosomiasis – a differential diagnosis to sexually transmitted disease: Genital itch and vaginal discharge as indicators of genital Schistosoma haematobium morbidity in a cross-sectional study in endemic rural Zimbabwe. Tropical Medicine and International Health 13, 15091517.

E. F. Kjetland , T. Mduluza , P. D. Ndhlovu , E. Gomo , L. Gwanzura , N. Midzi , P. R. Mason and S. G. Gundersen (2006 a). Genital schistosomiasis in women: a clinical 12-month in vivo study following treatment with praziquantel. Transactions of the Royal Society of Tropical Medicine and Hygiene 100, 740752.

E. F. Kjetland , P. D. Ndhlovu , E. Gomo , T. Mduluza , N. Midzi , L. Gwanzura , P. R. Mason and S. G. Gundersen (2006 b). Association between genital schistosomiasis and HIV in rural Zimbabwean women. AIDS 20, 593600.

S. D. Lawn , D. M. S. Karanja , P. Mwinzi , J. Andove , D. G. Colley , T. M. Folks and W. E. Secor (2000). The effect of treatment of schistosomiasis on blood plasma HIV-1 RNA concentration in coinfected individuals. AIDS 14, 24372443.

V. V. Laxman , B. Adamson and T. Mahmood (2008). Recurrent ectopic pregnancy due to Schistosoma hematobium. Journal of Obstetrics and Gynaecology 28, 461462.

M. Lebens , J.-B. Sun , C. Czerkinsky and J. Holmgren (2004). Current status and future prospects for a vaccine against schistosomiasis. Expert Review of Vaccines 3, 315328.

P. Leutscher , V. E. Ravaoalimalala , C. Raharisolo , C. E. Ramarakoto , M. Rasendramino , A. Raobelison , B. Vennervald and H. Feldmeier (1998). Clinical findings in female genital schistosomiasis in Madagascar. Tropical Medicine and International Health 3, 327332.

P. D. C. Leutscher , C.-E. Ramarakoto , S. Hoffmann , J. S. Jensen , V. Ramaniraka , B. Randrianasolo , C. Raharisolo and N. Christensen (2008). Coexistence of urogenital schistosomiasis and sexually transmitted infection in women and men living in an area where Schistosoma haematobium is endemic. Clinical Infectious Diseases 47, 775782.

P. D. C. Leutscher , C. M. Reimert , B. J. Vennervald , V. E. Ravaoalimalala , C. E. Ramarakoto , J. Serieye , A. Raobelison and P. Esterre (2000). Morbidity assessment in urinary schistosomiasis infection through ultrasonography and measurement of Eosinophil Cationic Protein (ECP) in urine. Tropical Medicine and International Health 5, 8893.

F. Liu , P. Chen , S.-J. Cui , Z.-Q. Wang and Z.-G. Han (2008). SjTPdb: Integrated transcriptome and proteome database and analysis platform for Schistosoma japonicum. BMC Genomics 9, art. no. 304.

E. S. Loker and S. V. Brant (2006). Diversification, dioecy and dimorphism in schistosomes. Trends in Parasitology 22, 521528.

S. Losada , N. Chacón , C. Colmenares , H. Bermúdez , A. Lorenzo , J. P. Pointier , A. Theron and O. Noya (2005). Schistosoma: Cross-reactivity and antigenic community among different species. Experimental Parasitology 111, 182190.

D. P. McManus and A. Loukas (2008). Current status of vaccines for schistosomiasis. Clinical Microbiology Reviews 21, 225242.

N. Midzi , A. E. Butterworth , T. Mduluza , S. Munyati , A. M. Deelder and G. J. van Dam (2009). Use of circulating cathodic antigen strips for the diagnosis of urinary schistosomiasis. Transactions of the Royal Society Tropical Medicine and Hygiene 103, 4551.

M. A. A. Mohsen , A. A. M. Hassan , S. M. El-Sewedy , T. Aboul-Azm , C. Maganitti , L. Airoldi (1999). Biomonotoring of N-nitroso compounds, nitrite and nitrate in the urine of Egyptian bladder cancer patients with or without Schistosoma haematobium infection. International Journal of Cancer 82, 789794.

D. H. Molyneux , P. J. Hotez , A. Fenwick , R. D. Newman , B. Greenwood and J. Sachs (2009). Neglected tropical diseases and the Global Fund. Lancet 373, 296297.

S. Mukaratirwa , H. R. Siegismund , T. K. Kristensen and S. K. Chandiwana (1996). Genetic structure and parasite compatibility of Bulinus globosus (Gastropoda: Planorbidae) from two areas of different endemicity of Schistosoma haematobium in Zimbabwe. International Journal for Parasitology 26, 269280.

C. Murta-Nascimento , B. J. Schmitz-Dräger , M. P. Zeegers , G. Steineck , M. Kogevinas , F. X. Real and N. Malats (2007). Epidemiology of urinary bladder cancer: From tumor development to patient's death. World Journal of Urology 25, 285295.

P. N. M. Mwinzi , D. M. S. Karanja , D. G. Colley , A. S. S. Orago and W. E. Secor (2001). Cellular immune responses of schistosomiasis patients are altered by human immunodeficiency virus type 1 coinfection. Journal of Infectious Diseases 184, 488496.

P. D. Ndhlovu , T. Mduluza , E. F. Kjetland , N. Midzi , L. Nyanga , S. G. Gundersen , H. Friis and E. Gomo (2007). Prevalence of urinary schistosomiasis and HIV in females living in a rural community of Zimbabwe: does age matter? Transactions of the Royal Society of Tropical Medicine and Hygiene 101, 433438.

S. O. Oladejo and I. E. Ofoezie (2006). Unabated schistosomiasis transmission in Erinle River Dam, Osun State, Nigeria: Evidence of neglect of environmental effects of development projects. Tropical Medicine and International Health 11, 843850.

E. Palumbo (2007). Association between schistosomiasis and cancer: A review. Infectious Diseases in Clinical Practice 15, 145148.

G. Poggensee and H. Feldmeier (2001). Female genital schistosomiasis: Facts and hypotheses. Acta Tropica 79, 193210.

G. Poggensee , H. Feldmeier and I. Krantz (1999). Schistosomiasis of the female genital tract: Public health aspects. Parasitology Today 15, 378381.

C. E. Ramarakoto , P. D. C. Leutscher , G. van Dam and N. O. Christensen (2008). Ultrasonographical findings in the urogenital organs in women and men infected with Schistosoma haematobium in northern Madagascar. Transactions of the Royal Society of Tropical Medicine and Hygiene 102, 767773.

A. Retel-Lauretin (1978). Appraising the role of certain diseases in sterility. An African example [Evaluation du role de certaines maladies dans l'infecondite. un exemple Africain]. Population 33, 101119.

G. Ribeiro-dos-Santos , S. Verjovski-Almeida and L. C. C. Leite (2006). Schistosomiasis – A century searching for chemotherapeutic drugs. Parasitology Research 99, 505521.

J. Richter (2003). The impact of chemotherapy on morbidity due to schistosomiasis. Acta Tropica 86, 161183.

T. M. Robinson and J. D. Boyer (2004). HIV-1 vaccines and co-infection. Expert Opinion on Biological Therapy 4, 14831492.

D. Rollinson , J. R. Stothard and V. R. Southgate (2001). Interactions between intermediate snail hosts of the genus Bulinus and schistosomes of the Schistosoma haematobium group. Parasitology 123, S245S260.

D Rollinson , J. P. Webster , S. Nyakaana and J. R. Stothard (2009). Genetic diversity of schistosomes and snails: significance for control. Parasitology 136, (in the Press).

J. W. Rudge , J. R. Stothard , M.-G. Basáñez , A. F. Mgeni , I. S. Khamis , A. N. Khamis and D. Rollinson (2008). Micro-epidemiology of urinary schistosomiasis in Zanzibar: Local risk factors associated with distribution of infections among schoolchildren and relevance for control. Acta Tropica 105, 4554.

W. E. Secor and J. B. Sundstrom (2007). Below the belt: New insights into potential complications of HIV-1/schistosome coinfections. Current Opinion in Infectious Diseases 20, 519523.

M. E. Shaw , P. A. Elder , A. Abbas and M. A. Knowles (1999). Partial allelotype of schistosomiasis-associated bladder cancer. International Journal of Cancer 80, 656661.

S. A. Sheweita , F. G. El-Shahat , M. A. Bazeed , M. R. Abu El-Maati and P. J. O'Connor (2004). Effects of Schistosoma haematobium infection on drug-metabolizing enzymes in human bladder cancer tissues. Cancer Letters 205, 1521.

C. Shiff , R. Veltri , J. Naples , J. Quartey , J. Otchere , W. Anyan , C. Marlow and K. Bosompem (2006). Ultrasound verification of bladder damage is associated with known biomarkers of bladder cancer in adults chronically infected with Schistosoma haematobium in Ghana. Transactions of the Royal Society of Tropical Medicine and Hygiene 100, 847854.

J. R. Stothard (2009). Improving control of African schistosomiasis: towards effective use of rapid diagnostic tests within an appropriate disease surveillance model. Transactions of the Royal Society of Tropical Medicine and Hygiene 103, 325332.

J. R. Stothard , A. F. Mgeni , S. Khamis , E. Seto , M. Ramsan and D. Rollinson (2002 a). Urinary schistosomiasis in schoolchildren on Zanzibar Island (Unguja), Tanzania: A parasitological survey supplemented with questionnaires. Transactions of the Royal Society of Tropical Medicine and Hygiene 96, 507514.

J. R. Stothard , A. F. Mgeni , S. Khamis , E. Seto , M. Ramsan , S. J. Hubbard , T. K. Kristensen and D. Rollinson (2002 b). Fresh from the fields. New Insights into the transmission biology of urinary schistosomiasis in Zanzibar. Transactions of the Royal Society of Tropical Medicine and Hygiene 96, 470475.

B. Swai , G. Poggensee , S. Mtweve and I. Krantz (2006). Female genital schistosomiasis as an evidence of a neglected cause for reproductive ill-health: A retrospective histopathological study from Tanzania. BMC Infectious Diseases 6, art. no. 134.

M. Talaat , S. Watts , S. Mekheimar , H. F. Ali and H. Hamed (2004). The social context of reproductive health in an Egyptian hamlet: A pilot study to identify female genital schistosomiasis. Social Science and Medicine 58, 515524.

J. E. Thomas , M. T. Bassett , L. B. Sigola and P. Taylor (1990). Relationship between bladder cancer incidence, Schistosoma haematobium infection, and geographical region in Zimbabwe. Transactions of the Royal Society of Tropical Medicine and Hygiene 84, 551553.

M. Troye-Blomberg and K. Berzins (2008). Immune interactions in malaria co-infections with other endemic infectious diseases: implications for the development of improved disease interventions. Microbes and Infection 10, 948952.

M. J. van der Werf , K. M. Bosompem and S. J. de Vlas (2003 a). Schistosomiasis control in Ghana: Case management and means for diagnosis and treatment within the health system. Transactions of the Royal Society of Tropical Medicine and Hygiene 97, 146152.

E. van Riet , F. C. Hartgers and M. Yazdanbakhsh (2007). Chronic helminth infections induce immunomodulation: Consequences and mechanisms. Immunobiology 212, 475490.

S. Verjovski-Almeida , R. DeMarco , E. A. Martins , P. E. Guimarães , E. P. Ojopi , A. C. Paquola , J. P. Piazza , M. Y. Nishiyama Jr. J. P. Kitajima , R. E. Adamson , P. D. Ashton , M. F. Bonaldo , P. S. Coulson , G. P. Dillon , L. P. Farias , S. P. Gregorio , P. L. Ho , R. A. Leite , L. C. Malaquias , R. C. Marques , P. A. Miyasato , A. L. Nascimento , F. P. Ohlweiler , E. M. Reis , M. A. Ribeiro , R. G. , G. C. Stukart , M. B. Soares , C. Gargioni , T. Kawano , V. Rodrigues , A. M. Madeira , R. A. Wilson , C. F. Menck , J. C. Setubal , L. C. Leite , E. Dias-Neto (2009). Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni. Nature Genetics 35, 148157.

B. L. Webster , V. R. Southgate , D. Timothy and J. Littlewood (2006). A revision of the interrelationships of Schistosoma including the recently described Schistosoma guineensis. International Journal for Parasitology 36, 947955.

C. A. Wright and G. C. Ross (1980). Hybrids between Schistosoma haematobium and S. mattheei and their identification by isoelectric focussing of enzymes. Transactions of the Royal Society of Tropical Medicine and Hygiene 74, 326332.

X. Wu , M. M. Ros , J. Gu and L. Kiemeney (2008). Epidemiology and genetic susceptibility to bladder cancer. BJU International 102, 12071215.

A. Zerlotini , M. Heiges , H. Wang , R. L. V. Moraes , A. J. Dominitini , J. C. Ruiz , J. C. Kissinger and G. Oliveira (2009). SchistoDB: A Schistosoma mansoni genome resource. Nucleic Acids Research 37, D579D58.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Parasitology
  • ISSN: 0031-1820
  • EISSN: 1469-8161
  • URL: /core/journals/parasitology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: