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Certain aspects of the host-parasite relationship of Nematospiroides dubius (Baylis): IV. The effect of the host's age on experimental infections in the mouse and rat

Published online by Cambridge University Press:  06 April 2009

Colin Dobson
Colin Dobson
Affiliation:
Department of Zoology, University of Sheffield
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Extract

1. The mouse and rat (an abnormal host) show an age resistance towards experimental infections with N. dubius.

2. This resistance was complicated by a different reaction in the male and female mouse and rat.

3. The rat exhibits age resistance despite being gonadectomized immediately after weaning.

4. Gonadectomy with replacement of the homologous sex hormone did not materially alter the age resistance of the host, but the administration of testosterone to the castrated male rat increased the numbers of larvae which penetrated the gut wall. Oestradiol decreased these numbers in the spayed female rat.

5. The relationships between the age resistance and the sex resistance of the hosts was discussed.

Type
Research Article
Information
Parasitology , Volume 52 , Issue 1-2 , May 1962 , pp. 31 - 40
Copyright
Copyright © Cambridge University Press 1962

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References

REFERENCES

Ackert, J. E., Edgar, S. A. & Frick, L. P. (1939). Goblet cells and age resistance of animals to parasitism. Trans. Amer. Micr. Soc. 58, 81–9.CrossRefGoogle Scholar
Bailey, W. S. (1949). Studies on calves experimentally infected with Cooperia punctata (v. Linstow, 1907) Ransom, 1907. Amer. J. Vet. Res. 10, 119–29.Google ScholarPubMed
Böhme, D. (1959). Nonspecific resistance and the reticuloendothelial system. Tohuku J. Exp. Med. 71, 121–35.CrossRefGoogle ScholarPubMed
Chandler, A. C. (1932). Experiments on resistance of rats to superinfection with the nematode, Nippostrongylus muris. Amer. J. Hyg. 16, 750–82.Google Scholar
Chandler, A. C. (1955). Introduction to Parasitology, 9th ed.New York: John Wiley and Sons.Google Scholar
Cort, W. W. & Otto, G. F. (1940). Immunity in Hookworm disease. Rev. Gastroent. 7, 2–13.Google Scholar
Dobson, C. (1961). Certain aspects of the host-parasite relationship of Nematospiroides dubius (Baylis). I. Resistance of male and female mice to experimental infections. Parasitology, 51, 173–9.CrossRefGoogle ScholarPubMed
Duca, C. J. (1939). Studies on age resistance against trypanosome infections: II. The resistance of rats of different age groups to Trypanosoma lewisi, and the blood response of rats infected with this parasite. Amer. J. Hyg. 29, 25–32.Google Scholar
Ebling, F. J. (1957). The action of testosterone and oestradiol on the sebacious glands and epidermis of the rat. J. Embryol. Exp. Morph. 5, 74–82.Google Scholar
Fülleborn, F., Dios, R. L. & Zuccarini, J. A. (1928). Bericht über eine im Auftrage der argentinischen Regierung unternommene Reise nach der Provinz Corrientes und nach Paraguay zum Studium der Hakenwurmbekämpfung, mit Bermerkungen zur Frage der Immunität gegenüber Hakenwürmern. Arch. Schiffs-u. Tropenhyg. 32, 441–81.Google Scholar
Goldberg, A. (1952). Effects of the nematode Oesophagostomum venulosum on sheep and goats. J. Parasit. 38, 35–47.CrossRefGoogle ScholarPubMed
Gordon, H. McL. (1950). Some aspects of parasitic gastro-enteritis of sheep. Aust. Vet. J. 26, 14–28.CrossRefGoogle ScholarPubMed
Graham, G. L. (1932). Studies on age-resistance of laboratory rats to Nippostrongylus muris (Yokogawa, 1920). J. Parasit. 19, 157–8.Google Scholar
Haley, A. J. (1958). Sex difference in the resistance of hamsters to infection with the rat nematode, Nippostrongylus muris. Exp. Parasit. 7, 338–48.CrossRefGoogle ScholarPubMed
Herlich, H. (1958). Further observations on the experimental host-parasite relations of the guinea pig and the ruminant parasite, Trichostrongylus colubriformis. J. Parasit. 44, 602.CrossRefGoogle Scholar
Herlich, H. (1960). Age resistance of cattle to nematodes of the gastrointestinal tract. J. Parasit. 46, 392–7.CrossRefGoogle ScholarPubMed
Herrick, C. A. (1928). A quantitative study of infections with Ancylostoma caninum in dogs. Amer. J. Hyg. 8, 125–57.Google Scholar
Lewert, R. M. (1958). Invasiveness of helminth larvae. Rice Inst. Pamphl. 45, 97–113.Google Scholar
Lewert, R. M. & Lee, C. L. (1954). Studies on the passage of helminth larvae through host tissues. I. Histochemical studies on the extracellular changes caused by penetrating larvae. II. Enzymatic activity of larvae in vitro and in vivo. J. Infect. Dis. 95, 13–51.CrossRefGoogle ScholarPubMed
Looss, A. (1911). The anatomy and life history of Agchylostoma duodenale Dub. Rec. Egypt. Govt. Sch. Med., 4, 613.Google Scholar
Lucker, J. T. (1953). Variability in effect of stomach worm, Haemonchus contortus, infections in lambs. Proc. 89th Ann. Meet (1952). Amer Vet. Med. Ass. 171–8.Google Scholar
Mathies, A. W. (1959). Certain aspects of the host-parasite relationship of Aspiculuris tetraptera, a mouse pinworm. I. Host specificity and age resistance. II. Sex resistance. Exp. Parasit. 8, 31–45.CrossRefGoogle Scholar
Mayhew, R. L. (1940). Studies on bovine gastro-intestinal parasites. II. Immunity to hookworm and nodular worm infection in calves. J. Parasit. 26, 345–57.CrossRefGoogle Scholar
Nolf, L. O. & Zaiman, H. (1941). The effect of host age on the number of Trichinella spiralis recovered from rats during the early period of infection. J. Parasit. Suppl. 27, 24.Google Scholar
Olson, L. J. (1959). The cellular response of white rats to Litomosoides carinii larvae as influenced by cortisone, age, and previous infection. J. Parasit. 45, 519–32.CrossRefGoogle ScholarPubMed
Ransom, B. H. & Foster, W. D. (1920). Observations on the life history of Ascaris lumbricoides. U.S. Dept. Agric. Bull. no. 817, 47 pp.Google Scholar
Sandground, J. H. (1929). A consideration of the relation of host-specificity of helminths and other metazoan parasites to the phenomena of age resistance and acquired immunity. Parasitology, 21, 227–55.CrossRefGoogle Scholar
Sarles, M. P. (1932). Development of an acquired resistance in rabbits by repeated infection with an intestinal nematode, Trichostrongylus calcaratus Ransom, 1911. J. Parasit. 19, 61–82.CrossRefGoogle Scholar
Sheldon, A. J. (1937). Successful infection of mice with Strongyloides ratti. J. Parasit. 23, 98.CrossRefGoogle Scholar
Vegors, H. H. (1954). Experimental infection of calves with Strongyloides papillosus (Nematoda). Amer. J. Vet. Res. 15, 429–33.Google ScholarPubMed
Weinstein, L. (1939). Effects of oestrogenic hormone and ovariectomy on normal antibody content of serum of mature rabbits. Yale J. Biol. Med. 11, 169–78.Google ScholarPubMed