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The nature and specificity of Negri bodies

Published online by Cambridge University Press:  06 April 2009

Hugh W. Acton  and
W. F. Harvey
Hugh W. Acton
Affiliation:
Assistant Director
W. F. Harvey
Affiliation:
Director, Pasteur Institute of India, Kasauli.
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Extract

By many observers Negri bodies have been considered to be parasitic in nature (Negri, 1903; Babes, 1907). Williams and Lowden (1906) go further and describe the life cycle of these bodies, regarding them as belonging to the Sporozoa, and give to them the name of Neuroryctes hydrophobiae. Calkins (1910), although he states that the parasitic nature of these bodies is not proven, still evidently inclines to that view. In his criticism of the work of Williams and Lowden he comes to differ from them as regards the classification of the supposed organisms. He thinks that their variable forms, the uninucleate condition, the occurrence of a state of distributed chromatin, and the budding phenomenon, are characteristic not of Sporozoa but of parasitic Rhizopods. His opinion is that the distributed chromatin masses in the Negri bodies are in all probability representative of the idiochromidia which are so characteristic of Rhizopods.

Type
Research Article
Information
Parasitology , Volume 4 , Issue 3 , October 1911 , pp. 255 - 272
Copyright
Copyright © Cambridge University Press 1911

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References

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