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Negative effect on early post-implantation pregnancy and progesterone levels in mice infected with the intestinal trematode Echinostoma caproni

Published online by Cambridge University Press:  06 April 2009

E. Bindseil  and
J. Hau
E. Bindseil
Affiliation:
Department of Pharmacology and Pathobiology, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark
J. Hau
Affiliation:
Department of Pharmacology and Pathobiology, Royal Veterinary and Agricultural University, 13 Bülowsvej, DK-1870 Frederiksberg C, Denmark
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Extract

Infection in mice (BALB/cABom) with the intestinal trematode Echinostoma caproni had a negative influence on pregnancy. The effect of the infection set in immediately following implantation (day 5 of pregnancy) resulting in fewer foetuses being present in infected mice on day 9 than in the controls. Ovulation, fertilization of eggs, and implantation itself were obviously not impaired. The infected mice had significantly lower serum progesterone levels on day 5 of pregnancy than the non-infected controls. It is speculated that the progesterone levels in the infected female mice were too low to secure early post-implantation gestation.

Keywords

Echinostoma capronimicepregnancyprogesterone
Type
Research Article
Information
Parasitology , Volume 102 , Issue 3 , June 1991 , pp. 387 - 390
Copyright
Copyright © Cambridge University Press 1991

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References

Bindseil, E. & Christensen, N. Ø. (1984). Thymus-independent crypt hyperplasia and villous atrophy in the small intestine of mice infected with the trematode Echinostoma revolutum. Parasitology 88, 431–8.Google Scholar
Bindseil, E., Andersen, L. L. I. & Hau, J. (1989). Reduced fertility in mice double-infected with Schistosoma mansoni and Echinostoma revolutum. Acta Tropica 46, 269–71.Google Scholar
Bindseil, E., Andersen, L. L. I. & Hau, J. (1990). Negative influence of extra-genital Schistosoma mansoni and Echinostoma caproni infections on fertility and maternal murine alpha-fetoprotein levels in the circulation of female mice. International Journal of Feto-maternal Medicine (in the Press.)Google Scholar
Cerruti, R. A. & Lyons, W. R. (1960). Mammogenic activities of the mid-gestational mouse placenta. Endocrinology 67, 884–7.Google Scholar
Finn, C. A. & McLaren, A. (1967). A study of the early stages of implantation in mice. Journal of Reproduction and Fertility 13, 259–67.Google Scholar
Finn, C. A. & Martin, L. (1969). Hormone secretion during early pregnancy in the mouse. Journal of Endocrinology 45, 57–65.Google Scholar
Hogan, B., Costantini, F. & Lacy, E. (1986). Manipulating the Mouse Embryo. A Laboratory Manual. New York: Cold Spring Harbor Laboratory.Google Scholar
Hooper, B. E. & Haelterman, E. O. (1969). Lesions of the gastro-intestinal tract of pigs infected with transmissible gastroenteritis. Canadian Journal of Comparative Medicine 33, 29–36.Google Scholar
Humphrey, K. W. (1967 a). The induction of implantation in the mouse after ovariectomy. Steroids 10, 591–600.Google Scholar
Humphrey, K. W. (1967 b). Attempted induction of implantation in ovariectomised mice with oestradiol and mast cell factors. Journal of Reproduction and Fertility 14, 493–6.CrossRefGoogle Scholar
Jacquetin, B., Schumacher, J. C., Raffi, F., Dervain, I., Kremer, C. & Renaud, J. (1977). Parasitoses et fertilité. In Infection et Fecondité (ed. Nenry-Suchet, J., Steg, A. & Constantin, A.), pp. 161–174. Paris: Masson.Google Scholar
Langer, A. & Chen, T. H. (1976). Hookworm disease in pregnancy with severe anemia. Obstetrics and Gynecology 42, 564–7.Google Scholar
Olson, L. J. & Richardson, J. A. (1968). Intestinal malabsorption of D-glucose in mice infected with Trichinella spiralis. Journal of Parasitology 54, 445–51.Google Scholar
Psychoyos, A. (1961). Perméabilité capillaire et decidualization uterine. Comptes Rendus hebdomadaire des Seances de l'Académie des Sciences 252, 1515–17.Google Scholar
Roberts-Thomson, I. C. & Mitchell, G. F. (1978). Giardiasis in mice I. Prolonged infections in certain mouse strains and hypothymic (nude) mice. Gastroenterology 75, 42–6.CrossRefGoogle ScholarPubMed
Shiner, M. & Doniach, I. (1960). Histopathological studies in steatorrhea. Gastroenterology 38, 419–40.CrossRefGoogle ScholarPubMed
Stephenson, L. S., Pond, W. G., Nesheim, M. C., Krook, L. P. & Crompton, D. W. T. (1980). Ascaris suum: Nutrient absorbtion, growth, and intestinal pathology in young pigs experimentally infected with 15-day-old larvae. Experimental Parasitology 49, 15–25.CrossRefGoogle Scholar
StGeorge, J. (1976). Intestinal parasite infection among parturients in Trinidad and Tobago. International Surgery 61, 222–5.Google Scholar
Stratton, J. A., Miller, R. D. & Schmidt, P. (1985). Effect of maternal parasitic disease on the neonate. American Journal of Reproductive Immunology and Microbiology 8, 141–2.Google Scholar
Swanson, V. L. & Thomassen, R. W. (1965). Pathology of the jejunal mucosa in tropical sprue. American Journal of Pathology 46, 511–51.Google Scholar
Symons, L. E. A. (1969). Pathology of gastrointestinal helminthiasis. International Review of Tropical Medicine 3, 49–100.Google Scholar
Symons, L. E. A. & Fairbairn, D. (1963). Biochemical pathology of the rat jejunum parasitized by the nematode Nippostrongylus brasiliensis. Experimental Parasitology 13, 284–304.CrossRefGoogle ScholarPubMed
Yoshinaga, K. (1982). Hormonal control of decidualization. In Proteins and Steroids in Early Pregnancy (ed. Beier, H. M. & Karlson, P.), pp. 15–26. Berlin, Heidelberg and New York: Springer-Verlag.CrossRefGoogle Scholar