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The importance of host age and sex to patterns of reinfection with Ascaris lumbricoides following mass anthelmintic treatment in a South Indian fishing community

  • D. B. Elkins (a1), Melissa Haswell-Elkins (a1) and R. M. Anderson (a1)
  • DOI: http://dx.doi.org/10.1017/S0031182000081749
  • Published online: 06 April 2009
Abstract
SUMMARY

Analysis of egg and worm counts of Ascaris recorded at various intervals following a mass anthelmintic treatment programme in a South Indian fishing community is presented. Three indices of infection in the community are compared, namely the prevalence and intensity of egg output (at 2, 6 and 11 months following treatment) and the number of worms expelled following an 11 month period of reinfection. Detailed examination of these measurements revealed significant associations with patient sex and age. The age-prevalence profile of Ascaris infection changed little over time (except immediately following treatment) with the peak prevalence found in the 5–9 year age group. Although 85% of both males and females harboured Ascaris initially, the prevalence following 11 months reinfection was decreased, due to a significantly lower proportion of males being reinfected. By the 11th month of reinfection, the age-intensity profiles of egg output were similar to those observed at initial treatment in the older age groups (10 years and above) and in male children (< 10 years). However, a dramatic increase in the egg output of female children, greatly exceeding the initial mean, was observed within a 6 month period of reinfection. The intensity of egg output did not accurately reflect the abundance of Ascaris recovered via drug-induced expulsion following an 11 month period of reinfection. Although the egg output attained preintervention levels, the average worm intensity reached only half the initial value. The trends in the sex- and age-intensity profiles were consistent at the two sampling dates and showed similar patterns to the egg output curves. The relevance of the results to helminth control and the monitoring of reinfection is discussed.

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R. M. Anderson (1986). The population dynamics and epidemiology of intestinal nematode infections. Transactions of the Royal Society of Tropical Medicine and Hygiene 80, 686–96.

R. M. Anderson & R. M. May (1982). Population dynamics of human helminth infections: control by chemotherapy. Nature, London 297, 557–63.

R. M. Anderson & R. M. May (1985). Helminth infections of humans: mathematical models, population dynamics and control. Advances in Parasitology 24, 1101.

D. A. P. Bundy (1986). Epidemiological aspects of Trichuris and trichuriasis in Caribbean communities. Trarisactions of the Royal Society of Tropical Medicine and Hygiene 80, 706–18.

J. H. Chai , B. S. Seo , S. H. Lee & S. Y. Cho (1983). Epidemiological studies on Ascaris lumbricoides reinfection in rural communities in Korea. II. Age-specific reinfection rates and familial aggregation of reinfected cases. Korean Journal of Parasitology 21, 142–9.

N. A. Croll , R. M. Anderson , T. W. Gyorkos & E. Ghadirian (1982). The population biology and control of Ascaris lumbricoides in a rural community in Iran. Transactions of the Royal Society of Tropical Medicine and Hygiene 76, 187–97.

D. B. Elkins , M. R. Haswell-Elkins & R. M. Anderson (1980). The epidemiology and control of intestinal helminths in the Pulicat Lake region of Southern India. I. Study design and pre- and posttreatment observations on Ascaris lumbricoides infection. Transactions of the Royal Society of Tropical Medicine and Hygiene 80, 774–92.

B. S. Seo , S. Y. Cho , J. Y. Chai & S. T. Hono (1980). Comparative efficacy of various interval mass treatment on Ascaris lumbricoides infection in Korea. Korean Journal of Parasitology 18, 145–51.

Thein-Hlaing, Than-Saw, Htay-Htay-Aye, Myint-Lwin & Thein-Maung-Myint (1984). Epidemiology and transmission dynamics of Ascaris lumbricoides in Okpo village, rural Burma. Transactions of the Royal Society ofTropial Medicine and Hygiene 78, 497504.

Thein-Hlaing, Than-Saw & Myint-Lwin (1987). Reinfection of people with Ascaris lumbricoides following single, 6-month and 12-month interval mass chemotherapy in Okpo village, rural Burma. Transactions of the Royal Society of Tropical Medicine and Hygiene 81, 140–6.

J. A. Walsh & K. S. Warren (1979). Selective primary health care. An interim strategy for disease control in developing countries. New England Journal of Medicine 301, 967–74.

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Parasitology
  • ISSN: 0031-1820
  • EISSN: 1469-8161
  • URL: /core/journals/parasitology
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