Skip to main content
×
Home
    • Aa
    • Aa

Glucose and cholesterol stabilization in patients with type 2 diabetes mellitus with depressive and anxiety symptoms by problem-solving therapy in primary care centers in Mexico City

  • Valerio Villamil-Salcedo (a1), Blanca E. Vargas-Terrez (a2), Jorge Caraveo-Anduaga (a3), Jorge González-Olvera (a4), Adriana Díaz-Anzaldúa (a5), José Cortés-Sotres (a6) and Magdalena Pérez-Ávila (a7)...
Abstract
Aim

The aim of this study was to determine if the problem-solving therapy (PST) helps control metabolic variables in patients with type 2 diabetes mellitus (T2DM) who show depressive and anxiety symptoms.

Background

T2DM is a chronic-degenerative multifactorial disease. It is considered one of the main public health problems in the world, and it represents an important social and economic burden. It is frequently associated with major depression and anxiety disorders, which are related with high glycated hemoglobin (HbA1c) concentrations and poor metabolic control.

Method

We initially included 123 patients diagnosed with T2DM from five primary care centers (PCC) in Mexico City. HbA1c, central glucose, and lipid profile were measured in each patient. In addition, the Kessler psychological distress scale (K-10), the Beck Depression Inventory, and the Beck Anxiety Inventory were applied at the beginning and, to those who continued, at the end of the PST, as well as four months later.

Findings

In total, 36 patients completed the PST and the follow-up. There was a significant decrease in depressive and anxiety symptoms (P<0.001), as well as in total cholesterol (P=0.002), HbA1c (P=0.05), and low-density lipoprotein (LDL) (P=0.022). The PST helps reduce depressive and anxiety symptoms and may help stabilize glucose and cholesterol up to four months. Further studies on this area are recommended. If our findings are confirmed, the PST could help improve the quality of life of thousands of individuals with psychiatric-metabolic co-morbidity who only visit PCC.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Glucose and cholesterol stabilization in patients with type 2 diabetes mellitus with depressive and anxiety symptoms by problem-solving therapy in primary care centers in Mexico City
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Glucose and cholesterol stabilization in patients with type 2 diabetes mellitus with depressive and anxiety symptoms by problem-solving therapy in primary care centers in Mexico City
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Glucose and cholesterol stabilization in patients with type 2 diabetes mellitus with depressive and anxiety symptoms by problem-solving therapy in primary care centers in Mexico City
      Available formats
      ×
Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Corresponding author
Correspondence to: Valerio Villamil-Salcedo, Department of Clinical Investigations Branch, National Institute of Psychiatry Ramón de la Fuente Muñiz, Calzada México-Xochimilco 101. Colonia San Lorenzo Huipulco, Delegación Tlalpan, CP 14370, Mexico City, Mexico. Email: valemil_2000@yahoo.com
References
Hide All
Aguilar-SalinasC., Velázquez-Monroy, Gómez-PérezO., González-ChávezF.J., Lara-EsquedaA., Molina-CuevasA., Rull-RodrigoV. and Tapia-ConyerJ.A. 2003: Characteristics of patients with type 2 diabetes Mexico. Diabetes Care 26, 20212026.
Alegre-DíazJ., WilliamH., López-CervantesM., LouisaG., RamirezR., MichaelH., BaigentC., McCarthyM.I., LewingtonS., CollinsR., WhitlockG., Tapia-ConyerR., PetoR., Kuri-MoralesP. and EmbersonJ.R. 2016: Diabetes and cause-specific mortality in Mexico City. New England Journal of Medicine 375, 19611971.
ArroyoC., HuF.B., RyanL.M., KawachiI., ColditzG., SpeizerF.E. and MansonJ. 2004: Depressive symptoms and risk of type 2 diabetes in women. Diabetes Care 27, 129133.
Australian Bureau of Statistics. 2001: Information paper: use of the Kessler psychological distress scale in ABS health surveys, Australia. Retrieved August 8, 2017 from http://www.abs.gov.au/ausstats/abs@.nsf/ProductsbyReleaseDate/4D5BD324FE8B415FCA2579D500161D57?OpenDocument
BeckA.T., SteerR.A. and CarbinM.G. 1988: Psychometric properties of the Beck Depression Inventory: twenty-five years of evaluation. Clinical Psychology Review 8, 77100.
BosmansJ., SchreudersB., van MarwijkH.W.J., SmitJ.H., van OppenP. and van TulderM.W. 2012: Cost-effectiveness of problem-solving treatment in comparison with usual care for primary care patients with mental health problems: a randomized trial. BMC Family Practice 13, 98.
BowerP. and GilbodyS. 2005: Managing common mental health disorders in primary care: conceptual models and evidence base. British Medical Journal 330, 839842.
BystritskyA., DanialJ. and KronemyerD. 2014: Interactions between diabetes and anxiety and depression: implications for treatment. Endocrinology and Metabolism Clinics of North America 43, 269283.
Castro-AkéA., Tovar-EspinosaJ. and Mendoza-CruzU. 2009: Trastorno depresivo y control glucémico en el paciente con diabetes mellitus 2. Revista Medica del Instituto Mexicano del Seguro Social 47, 377382.
Colunga-RodríguezC., García de AlbaJ.E., Salazar-EstradaJ.G. and Ángel-GonzálezM. 2008: Diabetes Tipo 2 y Depresión en Guadalajara, México. 2005. Revista de Salud Pública 10, 137149.
da RochaF., OgurtsovaK., LinnenkampU., GuariguataL., SeuringT., ZhangP., CavanD. and MakaroffL.E. 2016: IDF Diabetes Atlas estimates of 2014 global health expenditures on diabetes. Diabetes Research and Clinical Practice 117, 4854.
dos Reis QuintãoS. 2010: Tesis Doctoral. Validación de la versión portuguesa de la Escala de Ansiedad de Beck – BAI. Universidad de Salamanca, Salamanca.
FelgerJ.C. and LotrichF.E. 2013: Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications. Neuroscience 246, 199229.
Flores-HernándezS., Saturno-HernándezP.J., Reyes-MoralesH., Barrientos-GutiérrezT., VillalpandoS. and Hernández-ÁvilaM. 2015: Quality of diabetes care: the challenges of an increasing epidemic in Mexico. Results from two national health surveys (2006 and 2012). PLoS ONE 10, 115.
GaskL., SibbaldB. and CreedF. 1997: Evaluating models of working at the interface between mental health services and primary care. British Journal of Psychiatry 170, 611.
GuariguataL., WhitingD.R., HambletonI., BeagleyJ., LinnenkampU. and ShawJ.E. 2014: Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Research and Clinical Practice 103, 137149.
HarrisM.I., EastmanR.C., CowieC.C., FlegalK.M. and EberhardtE.M. 1999: Racial and ethnic differences in glycemic control of adults with type 2 diabetes. Diabetes Care 22, 403408.
Hassink-FrankeL.J.A. 2013. Problem-solving treatment during general practice residency. Feasibility, and effectiveness for patients with emotional symptoms in primary care. Nijmegen: Gildeprint Drukkerijen.
HernandezM.E., MendietaD., Pérez-TapiaM., BojalilR., Estrada-GarciaI., Estrada-ParraS. and PavónL. 2013: Effect of selective serotonin reuptake inhibitors and immunomodulator on cytokines levels: an alternative therapy for patients with major depressive disorder. Clinical & Developmental Immunology 2013, 267871.
IcksA., KruseJ., DraganoN., Broecker-PreussM., SlomianyU., MannK., JöckelK.H., ErbelR., GianiG. and MoebusS. 2008: Are symptoms of depression more common in diabetes? Results from the Heinz Nixdorf Recall study. Diabetic Medicine 25, 13301336.
International Diabetes Federation (IDF), Diabetes Atlas Group. 2015: Update of mortality attributable to diabetes for the IDF Diabetes Atlas: Estimates for the year 2013. Diabetes Research and Clinical Practice 109, 461465.
JuradoS., VillegasM.E., MéndezL., RodríguezF., LoperenaV. and VarelaR. 1998: La estandarización del Inventario de Depresión de Beck para los residentes de la ciudad de México. Salud Mental 21, 2631.
KabacoffR.I., SegalD.L., HersenM. and Van HasseltV.B. 1997: Psychometric properties and diagnostic utility of the Beck Anxiety Inventory and the State-Trait Anxiety Inventory with older adult psychiatric outpatients. Journal of Anxiety Disorders 11, 3347.
KendrickT., SimonsL., Mynors-WallisL., GrayA., LathleanJ., PickeringR., HarrisS., Rivero-AriasO., GerardK. and ThompsonC. 2006: Cost-effectiveness of referral for generic care or problem-solving treatment from community mental health nurses, compared with usual general practitoner care for common mental disorders: randomised controlled trial. British Journal of Psychiatry 189, 5059.
KesslerR., AndrewsG., ColpeL.J., HiripiE., MroczekD.K., NormandS.L.T., WaltersE.E. and ZaslavskyA.M. 2002: Short screening scales to monitor population prevalences and trends in non-specific psychological distress. Psychological Medicine 32, 959976.
KnolM.J., TwiskJ.W.R., BeekmanA.T.F., HeineR.J., SnoekF.J. and PouwerF. 2006: Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis. Diabetologia 49, 837845.
LeyferO.T., RubergJ.L. and Woodruff-BordenJ. 2006: Examination of the utility of the Beck Anxiety Inventory and its factors as a screener for anxiety disorders. Journal of Anxiety Disorders 20, 444458.
LustmanP.J., AndersonR.J., FreedlandK.E., de GrootM., CarneyR.M. and ClouseR.E. 2000: Depression and poor glycemic control: a meta-analytic review of the literature. Diabetes Care 23, 934942.
LustmanP.J., GriffithL.S., GavardJ.A. and ClouseR.E. 1992: Depression in adults with diabetes. Diabetes Care 15, 16311639.
MacDonaldW., RogersA., BlakemanT. and BowerP. 2008: Practice nurses and the facilitation of self-management in primary care. Journal of Advanced Nursing 62, 191199.
MoussaviS., ChatterjiS., VerdesE., TandonA., PatelV. and UstunB. 2007: Depression , chronic diseases , and decrements in health: results from the World Health Surveys. Lancet 370, 851858.
Mynors-WallisL.M., GathD.H., Lloyd-ThomasT.A. and TomlinsonD. 1995: Randomised controlled trial comparing problem solving treatment with amitriptyline and placebo for major depression in primary care. General Practice 310, 441445.
PrinceM., PatelV., SaxenaS., MajM., MaselkoJ., PhillipsM.R. and RahmanA. 2007: No health without mental health. Lancet 370, 859877.
Rivas-AcuñaV., García-BarjauH., Cruz-LeónA., Morales-RamónF., Enríquez-MartínezR.M. and Román-AlvarezJ. 2011: Prevalencia de ansiedad y depresión en las personas con diabetes mellitus tipo 2. Salud en Tabasco 17, 3035.
SanzJ., PerdigónA.L. and VázquezC. 2003: Adaptación española del Inventario para la Depresión de Beck-II (BDI-II): 2. Propiedades psicométricas en población general. Clínica y Salud 14, 249280.
SanzJ. and VázquezC. 1998: Fiabilidad, validez y datos normativos del inventario para la depresión de Beck. Psicothema 10, 303318.
SaydahS.H., FradkinJ. and CowieC.C. 2004: Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. Journal of American Medical Association 291, 335342.
Secretaría de Salud 2016. Encuesta Nacional de Salud y Nutrición de Medio Camino 2016. (ENSANUT MC 2016), Primera edition. Ciudad de México: Secretaría de salud.
UlusoyM., SahinN. and ErkmenH. 1998: Turkish version of the Beck Anxiety Inventory: psychometric properties. Journal of Cognitive Psychotherapy 12, 163172. Retrieved from http://scholar.google.com/scholar?hl=en&btnG=Search&q=intitle:Turkish+Version+of+the+Beck+Anxiety+Inventory+:+Psychometric+Properties#0%5Cnhttp://scholar.google.com/scholar?hl=en&btnG=Search&q=intitle:Turkish+version+of+the+Beck+Anxiety+Inventory:+psychomet.
Vargas-TerrezB., Villamil-SalcedoV., Rodríguez-EstradaC., Pérez-RomeroJ. and Cortés-SotresJ. 2011: Validación de la escala Kessler 10 (K-10) en la detección de depresión y ansiedad en el primer nivel de atención. Propiedades psicométricas. Salud Mental 34, 323331.
Vargas-TerrezB., Villamil-SalcedoV. and Pérez-RomeroJ. 2012: Los modelos de atención primaria en salud mental: el caso de México. Atencion primaria/Sociedad Española de Medicina de Familia y Comunitaria 44, 441442.
Vargas-TerrezB.E. and Villamil-SalcedoV. 2013. Terapia de Solución de Problemas para el Cuidado de la Salud Mental en el Primer Nivel de Atención – Guía de Intervención Breve - México, Primera edition. Ciudad de México: Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz.
Villamil-SalcedoV., EstradaJ.L., Lucatero-MoraD., López-FavelaM., ViverosM., Maldonado-MoraJ.A. and Del Toro-GodínezM. 2006: Experiencia de un modelo de atención primaria en salud mental (Fase piloto). Revista de Psiquiatría 22, 712.
Villamil-SalcedoV., Vargas-TerrezB.E. and Díaz-AnzaldúaA. 2017: Collaborative Care model in mental health. Scope and experiences after three years of activity in Mexico City. Primary Health Care Research & Development 18, 18. Retrieved August 8, 2017 from https://www.cambridge.org/core/article/div-class-title-collaborative-care-model-in-mental-health-scope-and-experiences-after-three-years-of-activity-in-mexico-city-div/1AC8F1EDFD21C01B53804DFA3119F480.
WhitingD.R., GuariguataL., WeilC. and ShawJ. 2011: IDF Diabetes Atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Research and Clinical Practice 94, 311321.
World Health Organization. 2004: Prevention of Mental Disorders. Effective interventions and policy options. Geneva: WHO.
World Health Organization. 2010: MhGAP Intervention Guide for mental, neurological and substance use disorders in non-specialized health settings. Geneva: WHO.
World Health Organization. 2016: Global report on diabetes. Geneva: WHO. Retrieved August 8, 2017 from http://www.who.int/about/licensing/ copyright_form/index.html
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Primary Health Care Research & Development
  • ISSN: 1463-4236
  • EISSN: 1477-1128
  • URL: /core/journals/primary-health-care-research-and-development
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords:

Metrics

Full text views

Total number of HTML views: 28
Total number of PDF views: 71 *
Loading metrics...

Abstract views

Total abstract views: 106 *
Loading metrics...

* Views captured on Cambridge Core between 5th September 2017 - 22nd October 2017. This data will be updated every 24 hours.