Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-08T16:40:35.220Z Has data issue: false hasContentIssue false

Chlorpromazine equivalents: a consensus of opinion for both clinical and research applications

Published online by Cambridge University Press:  02 January 2018

Maria Atkins*
Affiliation:
Napsbury Hospital, London Colney, near St Albans, Herts AL2 1AA
Adrian Burgess
Affiliation:
Charing Cross and Westminster Medical School
Clare Bottomley
Affiliation:
Chelsea and Westminster Hospital
Massimo Riccio
Affiliation:
Charing Cross and Westminster Hospital and The Priory Hospital, London SW15
*
Correspondence
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A consensus of available information is used to produce a working table of conversion for the most commonly used drugs to chlorpromazine equivalents. A user-friendly computer program has also been developed from this information. The use of the concept In the clinical setting and for research purposes is briefly discussed.

Type
Drug Information Quarterly
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
Copyright © 1997 The Royal College of Psychiatrists

References

Association of The British Pharmaceutical Industry (1994) BPI Data Sheet Compendium 1994–95. London: ABPI Google Scholar
Bazire, S. (1994) Psychotropic Drug Directory. Lancaster Quay Publishing Ltd. Google Scholar
Beckmann, H. & Laux, G. (1990) Guidelines for the dosage of antipsychotic drugs. Acta Psychiatrica Scandinavica, 82 (Suppl. 358), 6366.CrossRefGoogle Scholar
British Medical Association & Royal Pharmaceutical Society of Great Britain (1994) British National Formulary (1994). pp. 146153. Bath: Bath Press.Google Scholar
Foster, P. (1989) Neuroleptic equivalence. The Pharmaceutical Journal, 243, 431432.Google Scholar
Kane, J. M. (1994) The use of higher-dose antipsychotic medication. British Journal of Psychiatry, 164, 431432.Google Scholar
Mehtonen, A., Aranko, K., Malkonen, L., et al (1991) A survey of sudden death associated with the use of antipsychotic or antidepressant drugs: 49 cases in Finland. Acta Psychiatrica Scandinavica, 84, 5864.CrossRefGoogle ScholarPubMed
Mullen, R., Caan, A. W. & Smith, S. (1994) Perception of equivalent doses of neuroleptic drugs. Psychiatric Bulletin, 18, 335337.CrossRefGoogle Scholar
Rey, M. J., Schulz, P., Costa, C., et al (1989) Guidelines for the dosage of neuroleptics. 1: Chlorpromazine equivalents of orally administered neuroleptics. International Clinical Psychopharmacology, 4, 95104.Google Scholar
Schulz, P., Rey, M. J., Dick, P., et al (1989) Guidelines for the dosage of neuroleptics. 11: Changing from daily oral to long acting injectable neuroleptics. International Clinical Psychopharmacology, 4, 105114.Google Scholar
Thompson, C. (1994) The use of high-dose antipsychotic medication. British Journal of Psychiatry, 164, 448458.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.