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Genetic and environmental influences on anorexia nervosa syndromes in a population–based twin sample

  • K. L. KLUMP (a1), K. B. MILLER (a1), P. K. KEEL (a1), M. McGUE (a1) and W. G. IACONO (a1)...


Background. Genetic and environmental influences on broadly-defined anorexia nervosa (AN) syndrome were examined in a population-based twin sample.

Methods. AN syndrome was assessed in 672 female 17 year-old twins using structured interviews and a self-report questionnaire.

Results. Twenty-six probands with AN syndrome were identified. Biometrical model-fitting analyses indicated that genetic and non-shared environmental factors accounted for 74 % and 26 % of the variance in AN syndrome, respectively.

Conclusions. Findings support previous research indicating significant genetic and non-shared environmental influences on AN syndromes.


Corresponding author

Address for correspondence: Dr Kelly L. Klump, Department of Psychology, Michigan State University, 129 Psychology Research Building, East Lansing, MI 48824, USA.


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