Aasly J, Storsaeter O, Nilsen G, Smevik O, Rinck P (1993). Minor structural brain changes in young drug abusers. A magnetic resonance study. Acta Neurologica Scandinavica 87, 210–214.
Amen DG, Waugh M (1998). High resolution brain SPECT imaging of marijuana smokers with AD/HD. Journal of Psychoactive Drugs 30, 209–214.
Arnone D, Barrick TR, Chengappa S, Mackay CE, Clark CA, Abou-Saleh MT (2008). Corpus callosum damage in heavy marijuana use: preliminary evidence from diffusion tensor tractography and tract-based spatial statistics. Neuroimage 41, 1067–1074.
Arseneault L, Cannon M, Witton J, Murray RM (2004). Causal association between cannabis and psychosis: examination of the evidence. British Journal of Psychiatry 184, 110–117.
Ashtari M, Cervellione K, Cottone J, Ardekani BA, Kumra S (2009). Diffusion abnormalities in adolescents and young adults with a history of heavy cannabis use. Journal of Psychiatric Research 43, 189–204.
Bechara A, Dolan S, Denburg N, Hindes A, Anderson SW, Nathan PE (2001). Decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in alcohol and stimulant abusers. Neuropsychologia 39, 376–389.
Berger A, Posner MI (2000). Pathologies of brain attentional networks. Neuroscience and Biobehavioral Reviews 24, 3–5.
Block RI, O'Leary DS, Ehrhardt JC, Augustinack JC, Ghoneim MM, Arndt S, Hall JA (2000 a). Effects of frequent marijuana use on brain tissue volume and composition. Neuroreport 11, 491–496.
Block RI, O'Leary DS, Hichwa RD, Augustinack JC, Boles Ponto LL, Ghoneim MM, Arndt S, Hurtig RR, Watkins GL, Hall JA, Nathan PE, Andreasen NC (2002). Effects of frequent marijuana use on memory-related regional cerebral blood flow. Pharmacology, Biochemistry, and Behavior 72, 237–250.
Block RI, O'Leary DS, Hichwa RD, Augustinack JC, Ponto LL, Ghoneim MM, Arndt S, Ehrhardt JC, Hurtig RR, Watkins GL, Hall JA, Nathan PE, Andreasen NC (2000 b). Cerebellar hypoactivity in frequent marijuana users. Neuroreport 11, 749–753.
Bolla KI, Brown K, Eldreth D, Tate K, Cadet JL (2002). Dose-related neurocognitive effects of marijuana use. Neurology 59, 1337–1343.
Bolla KI, Eldreth DA, Matochik JA, Cadet JL (2005). Neural substrates of faulty decision-making in abstinent marijuana users. Neuroimage 26, 480–492.
Borgwardt SJ, Allen P, Bhattacharyya S, Fusar-Poli P, Crippa JA, Seal ML, Fraccaro V, Atakan Z, Martin-Santos R, O'Carroll C, Rubia K, McGuire PK (2008). Neural basis of Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD): effects during response inhibition. Biological Psychiatry 64, 966–973.
Bossong MG, van Berckel BN, Boellaard R, Zuurman L, Schuit RC, Windhorst AD, van Gerven JM, Ramsey NF, Lammertsma AA, Kahn RS (2009). Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum. Neuropsychopharmacology 34, 759–766.
Campbell AM, Evans M, Thomson JL, Williams MJ (1971). Cerebral atrophy in young cannabis smokers. Lancet 2, 1219–1224.
Chang L, Chronicle EP (2007). Functional imaging studies in cannabis users. Neuroscientist 13, 422–432.
Chang L, Yakupov R, Cloak C, Ernst T (2006). Marijuana use is associated with a reorganized visual-attention network and cerebellar hypoactivation. Brain 129, 1096–1112.
Co BT, Goodwin DW, Gado M, Mikhael M, Hill SY (1977). Absence of cerebral atrophy in chronic cannabis users. Evaluation by computerized transaxial tomography. Journal of the American Medical Association 237, 1229–1230.
Crippa JA, Lacerda AL, Amaro E, Busatto FG, Zuardi AW, Bressan RA (2005). Brain effects of cannabis – neuroimaging findings [in Portuguese]. Revista Brasileira de Psiquiatria 27, 70–78.
Crippa JA, Zuardi AW, Garrido GE, Wichert-Ana L, Guarnieri R, Ferrari L, Azevedo-Marques PM, Hallack JE, McGuire PK, Filho Busatto G (2004). Effects of cannabidiol (CBD) on regional cerebral blood flow. Neuropsychopharmacology 29, 417–426.
DeLisi LE (2008). The effect of cannabis on the brain: can it cause brain anomalies that lead to increased risk for schizophrenia? Current Opinion in Psychiatry 21, 140–150.
DeLisi LE, Bertisch HC, Szulc KU, Majcher M, Brown K, Bappal A, Ardekani BA (2006). A preliminary DTI study showing no brain structural change associated with adolescent cannabis use. Harm Reduction Journal 3, 17.
Eldreth DA, Matochik JA, Cadet JL, Bolla KI (2004). Abnormal brain activity in prefrontal brain regions in abstinent marijuana users. Neuroimage 23, 914–920.
Freund TF, Katona I, Piomelli D (2003). Role of endogenous cannabinoids in synaptic signaling. Physiological Reviews 83, 1017–1066.
Fusar-Poli P, Crippa JA, Bhattacharyya S, Borgwardt SJ, Allen P, Martin-Santos R, Seal M, Surguladze SA, O'Carrol C, Atakan Z, Zuardi AW, McGuire PK (2009). Distinct effects of (delta)9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing. Archives of General Psychiatry 66, 95–105.
Gonzalez R (2007). Acute and non-acute effects of cannabis on brain functioning and neuropsychological performance. Neuropsychology Review 17, 347–361.
Gorelick DA, Heishman SJ (2006). Methods for clinical research involving cannabis administration. Methods in Molecular Medicine 123, 235–253.
Gruber SA, Yurgelun-Todd DA (2005). Neuroimaging of marijuana smokers during inhibitory processing: a pilot investigation. Brain Research. Cognitive Brain Research 23, 107–118.
Hall W, Solowij N (1998). Adverse effects of cannabis. Lancet 352, 1611–1616.
Hannerz J, Hindmarsh T (1983). Neurological and neuroradiological examination of chronic cannabis smokers. Annals of Neurology 13, 207–210.
Hermann D, Sartorius A, Welzel H, Walter S, Skopp G, Ende G, Mann K (2007). Dorsolateral prefrontal cortex N-acetylaspartate/total creatine (NAA/tCr) loss in male recreational cannabis users. Biological Psychiatry 61, 1281–1289.
Hirst RA, Lambert DG, Notcutt WG (1998). Pharmacology and potential therapeutic uses of cannabis. British Journal of Anaesthesia 81, 77–84.
Hollister LE (1986). Health aspects of cannabis. Pharmacological Reviews 38, 1–20.
Jacobsen LK, Mencl WE, Westerveld M, Pugh KR (2004). Impact of cannabis use on brain function in adolescents. Annals of the New York Academy of Sciences 1021, 384–390.
Jacobsen LK, Pugh KR, Constable RT, Westerveld M, Mencl WE (2007). Functional correlates of verbal memory deficits emerging during nicotine withdrawal in abstinent adolescent cannabis users. Biological Psychiatry 61, 31–40.
Jager G, Kahn RS, Van Den Brink W, Van Ree JM, Ramsey NF (2006). Long-term effects of frequent cannabis use on working memory and attention: an fMRI study. Psychopharmacology (Berlin) 185, 358–368.
Jager G, Van Hell HH, De Win MM, Kahn RS, Van Den Brink W, Van Ree JM, Ramsey NF (2007). Effects of frequent cannabis use on hippocampal activity during an associative memory task. Journal of the European College of Neuropsychopharmacology 17, 289–297.
Kanayama G, Rogowska J, Pope HG, Gruber SA, Yurgelun-Todd DA (2004). Spatial working memory in heavy cannabis users: a functional magnetic resonance imaging study. Psychopharmacology (Berlin) 176, 239–247.
Kuehnle J, Mendelson JH, Davis KR, New PF (1977). Computed tomographic examination of heavy marijuana smokers. Journal of the American Medical Association 237, 1231–1232.
Li CS, Milivojevic V, Constable RT, Sinha R (2005). Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals. Psychiatry Research 140, 271–280.
Lundqvist T (2005). Cognitive consequences of cannabis use: comparison with abuse of stimulants and heroin with regard to attention, memory and executive functions. Pharmacology, Biochemistry, and Behavior 81, 319–330.
Lundqvist T, Jonsson S, Warkentin S (2001). Frontal lobe dysfunction in long-term cannabis users. Neurotoxicology and Teratology 23, 437–443.
Mathew RJ, Tant S, Burger C (1986). Regional cerebral blood flow in marijuana smokers. British Journal of Addiction 81, 567–571.
Mathew RJ, Wilson WH (1993). Acute changes in cerebral blood flow after smoking marijuana. Life Sciences 52, 757–767.
Mathew RJ, Wilson WH, Chiu NY, Turkington TG, DeGrado TR, Coleman RE (1999). Regional cerebral blood flow and depersonalization after tetrahydrocannabinol administration. Acta Psychiatrica Scandinavica 100, 67–75.
Mathew RJ, Wilson WH, Coleman RE, Turkington TG, DeGrado TR (1997). Marijuana intoxication and brain activation in marijuana smokers. Life Sciences 60, 2075–2089.
Mathew RJ, Wilson WH, Humphreys DF, Lowe JV, Wiethe KE (1992 a). Regional cerebral blood flow after marijuana smoking. Journal of Cerebral Blood Flow and Metabolism 12, 750–758.
Mathew RJ, Wilson WH, Humphreys DF, Lowe JV, Wiethe KE (1992 b). Changes in middle cerebral artery velocity after marijuana. Biological Psychiatry 32, 164–169.
Mathew RJ, Wilson WH, Tant SR (1989). Acute changes in cerebral blood flow associated with marijuana smoking. Acta Psychiatrica Scandinavica 79, 118–128.
Mathew RJ, Wilson WH, Turkington TG, Coleman RE (1998). Cerebellar activity and disturbed time sense after THC. Brain Research 797, 183–189.
Mathew RJ, Wilson WH, Turkington TG, Hawk TC, Coleman RE, DeGrado TR, Provenzale J (2002). Time course of tetrahydrocannabinol-induced changes in regional cerebral blood flow measured with positron emission tomography. Psychiatry Research 116, 173–185.
Matochik JA, Eldreth DA, Cadet JL, Bolla KI (2005). Altered brain tissue composition in heavy marijuana users. Drug and Alcohol Dependence 77, 23–30.
Murphy K, Dixon V, LaGrave K, Kaufman J, Risinger R, Bloom A, Garavan H (2006). A validation of event-related FMRI comparisons between users of cocaine, nicotine, or cannabis and control subjects. American Journal of Psychiatry 163, 1245–1251.
Nestor L, Roberts G, Garavan H, Hester R (2008). Deficits in learning and memory: parahippocampal hyperactivity and frontocortical hypoactivity in cannabis users. Neuroimage 40, 1328–1339.
O'Leary DS, Block RI, Flaum M, Schultz SK, Boles Ponto LL, Watkins GL, Hurtig RR, Andreasen NC, Hichwa RD (2000). Acute marijuana effects on rCBF and cognition: a PET study. Neuroreport 11, 3835–3841.
O'Leary DS, Block RI, Koeppel JA, Flaum M, Schultz SK, Andreasen NC, Ponto LB, Watkins GL, Hurtig RR, Hichwa RD (2002). Effects of smoking marijuana on brain perfusion and cognition. Neuropsychopharmacology 26, 802–816.
O'Leary D, Block RI, Koeppel JA, Schultz SK, Magnotta VA, Boles Ponto L, Watkins FL, Hichwa RD (2007). Effects of smoking marijuana on focal attention and brain flow. Human Psychopharmacology 22, 135–148.
O'Leary DS, Block RI, Turner BM, Koeppel J, Magnotta VA, Ponto LB, Watkins GL, Hichwa RD, Andreasen NC (2003). Marijuana alters the human cerebellar clock. Neuroreport 14, 1145–1151.
Pertwee RG, Ross RA (2002). Cannabinoid receptors and their ligands. Prostaglandins, Leukotrienes and Essential Fatty Acids 66, 101–121.
Phan KL, Angstadt M, Golden J, Onyewuenyi I, Popovska A, de Wit H (2008). Cannabinoid modulation of amygdala reactivity to social signals of threat in humans. Journal of Neuroscience 28, 2313–2319.
Pillay SS, Rogowska J, Kanayama G, Jon DI, Gruber S, Simpson N, Cherayil M, Pope HG, Yurgelun-Todd DA (2004). Neurophysiology of motor function following cannabis discontinuation in chronic cannabis smokers: an fMRI study. Drug and Alcohol Dependence 76, 261–271.
Quickfall J, Crockford D (2006). Brain neuroimaging in cannabis use: a review. Journal of Neuropsychiatry and Clinical Neuroscience 18, 318–332.
Ranganathan M, D'Souza DC (2006). The acute effects of cannabinoids on memory in humans: a review. Psychopharmacology (Berlin) 188, 425–444.
Roser P, Vollenweider FX, Kawohl W (2008). Potential antipsychotic properties of central cannabinoid (CB(1)) receptor antagonists. World Journal of Biological Psychiatry 7, 1–12.
Rypma B, D'Esposito M (2000). Isolating the neural mechanisms of age-related changes in human working memory. Nature Neuroscience 3, 509–515.
Schneider M (2008). Puberty as a highly vulnerable development period for the consequences of cannabis exposure. Addiction Biology 13, 253–263.
Schweinsburg AD, Schweinsburg BC, Cheung EH, Brown GG, Brown SA, Tapert SF (2005). fMRI response to spatial working memory in adolescents with comorbid marijuana and alcohol use disorders. Drug and Alcohol Dependence 79, 201–210.
Sevy S, Smith GS, Ma Y, Dhawan V, Chaly T, Kingsley PB, Kumra S, Abdelmessih S, Eidelberg D (2008). Cerebral glucose metabolism and D2/D3 receptor availability in young adults with cannabis dependence measured with positron emission tomography. Psychopharmacology (Berlin) 197, 549–556.
Sneider JT, Pope HG Jr., Silveri MM, Simpson NS, Gruber SA, Yurgelun-Todd DA (2006). Altered regional blood volume in chronic cannabis smokers. Experimental and Clinical Psychopharmacology 14, 422–428.
Sneider JT, Pope HG Jr., Silveri MM, Simpson NS, Gruber SA, Yurgelun-Todd DA (2008). Differences in regional blood volume during a 28-day period of abstinence in chronic cannabis smokers. European Neuropsychopharmacology 18, 612–619.
Solowij N, Stephens RS, Roffman RA, Babor T, Kadden R, Miller M, Christiansen K, McRee B, Vendetti J (2002). Cognitive functioning of long-term heavy cannabis users seeking treatment. Journal of the American Medical Association 287, 1123–1131.
Tunving K, Thulin SO, Risberg J, Warkentin S (1986). Regional cerebral blood flow in long-term heavy cannabis use. Psychiatry Research 17, 15–21.
Tzilos GK, Cintron CB, Wood JB, Simpson NS, Young AD, Pope HG Jr., Yurgelun-Todd DA (2005). Lack of hippocampal volume change in long-term heavy cannabis users. American Journal on Addictions 14, 64–72.
Vernon PA (1983). Speed of information processing and general intelligence. Intelligence 7, 53–70.
Volkow ND, Fowler JS, Wang GJ (2003). The addicted human brain: insights from imaging studies. Journal of Clinical Investigation 111, 1444–1451.
Volkow ND, Gillespie H, Mullani N, Tancredi L, Grant C, Ivanovic M, Hollister L (1991). Cerebellar metabolic activation by delta-9-tetrahydro-cannabinol in human brain: a study with positron emission tomography and 18F-2-fluoro-2-deoxyglucose. Psychiatry Research 40, 69–78.
Volkow ND, Gillespie H, Mullani N, Tancredi L, Grant C, Valentine A, Hollister L (1996). Brain glucose metabolism in chronic marijuana users at baseline and during marijuana intoxication. Psychiatry Research 67, 29–38.
Voruganti LN, Slomka P, Zabel P, Mattar A, Awad AG (2001). Cannabis induced dopamine release: an in-vivo SPECT study. Psychiatry Research 107, 173–177.
Voytek B, Berman SM, Hassid BD, Simon SL, Mandelkern MA, Brody AL, Monterosso J, Ling W, London ED (2005). Differences in regional brain metabolism associated with marijuana abuse in methamphetamine abusers. Synapse 57, 113–115.
Ward PB, Solowij N, Peters R, Otton J, Chesher G, Grenyer B (2002). An fMRI study of regional brain volumes in long-term cannabis users. Journal of Psychopharmacology 16 (Suppl. 3), A56.
Watson SJ, Benson JA Jr., Joy JE (2000). Marijuana and medicine: assessing the science base: a summary of the 1999 Institute of Medicine report. Archives of General Psychiatry 57, 547–552.
Weinstein A, Brickner O, Lerman H, Greemland M, Bloch M, Lester H, Chisin R, Mechoulam R, Bar-Hamburger R, Freedman N, Even-Sapir E (2008). Brain imaging study of the acute effects of Delta9-tetrahydrocannabinol (THC) on attention and motor coordination in regular users of marijuana. Psychopharmacology (Berlin) 196, 119–131.
Wiesbeck GA, Taeschner KL (1991). A cerebral computed tomography study of patients with drug-induced psychoses. European Archives of Psychiatry and Clinical Neuroscience 241, 88–90.
Williamson EM, Evans FJ (2000). Cannabinoids in clinical practice. Drugs 60, 1303–1314.
Wilson W, Mathew R, Turkington T, Hawk T, Coleman RE, Provenzale J (2000). Brain morphological changes and early marijuana use: a magnetic resonance and positron emission tomography study. Journal of Addictive Diseases 19, 1–22.
Yücel M, Solowij N, Respondek C, Whittle S, Fornito A, Pantelis C, Lubman DI (2008). Regional brain abnormalities associated with long-term heavy cannabis use. Archives of General Psychiatry 65, 694–701.
Yurgelun-Todd DA, Gruber SA, Hanson RA, Baird AA, Renshaw PF, Pope HG (1998). Residual effects of marijuana use: an fMRI study. In Problems of drug dependence. Proceedings of the 60th Annual Scientific Meeting. The College on Problems of Drug Dependence (ed. Harris L. S.). NIDA Research Monograph 179, 78.
Zuardi AW (2006). History of cannabis as a medicine: a review. Revista Brasileira de Psiquiatria 28, 153–157.
Zuardi AW, Shirakawa I, Finkelfarb E, Karniol IG (1982). Action of cannabidiol on the anxiety and others effects produced by delta 9-THC in normal subjects. Psychopharmacology (Berlin) 76, 245–250.