Skip to main content
×
Home
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 40
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Fonseca-Pedrero, E. Debbané, M. Schneider, M. Badoud, D. and Eliez, S. 2016. Schizotypal traits in adolescents with 22q11.2 deletion syndrome: validity, reliability and risk for psychosis. Psychological Medicine, Vol. 46, Issue. 05, p. 1005.


    Ma, Guorong Fan, Hongying Shen, Chanchan and Wang, Wei 2016. Genetic and Neuroimaging Features of Personality Disorders: State of the Art. Neuroscience Bulletin, Vol. 32, Issue. 3, p. 286.


    Gjerde, L. C. Czajkowski, N. Røysamb, E. Ystrom, E. Tambs, K. Aggen, S. H. Ørstavik, R. E. Kendler, K. S. Reichborn-Kjennerud, T. and Knudsen, G. P. 2015. A longitudinal, population-based twin study of avoidant and obsessive-compulsive personality disorder traits from early to middle adulthood. Psychological Medicine, Vol. 45, Issue. 16, p. 3539.


    Newton-Howes, Giles Clark, Lee Anna and Chanen, Andrew 2015. Personality disorder across the life course. The Lancet, Vol. 385, Issue. 9969, p. 727.


    Westermeyer, Joseph Yoon, Gihyun Amundson, Carla Warwick, Marion and Kuskowski, Michael A. 2015. Personality disorders in adopted versus non-adopted adults. Psychiatry Research, Vol. 226, Issue. 2-3, p. 446.


    Zhang, TianHong Li, HuiJun Tang, YingYing Li, Hui Zheng, LiNa Guo, Qian Zhao, ShanShan Zhuo, KaiMing Qian, ZhenYing Wang, LanLan Dai, YunFei Chow, Annabelle Li, ChunBo Jiang, KaiDa Wang, JiJun and Xiao, ZePing 2015. Screening schizotypal personality disorder for detection of clinical high risk of psychosis in Chinese mental health services. Psychiatry Research, Vol. 228, Issue. 3, p. 664.


    Birkeland, Søren Fryd 2014. Delusional Psychosis in Individuals Diagnosed with Paranoid Personality Disorder: A Qualitative Study. Current Psychology, Vol. 33, Issue. 2, p. 219.


    Gjerde, Line C. Røysamb, Espen Czajkowski, Nikolai Knudsen, Gun Peggy Østby, Kristian Tambs, Kristian Kendler, Kenneth S. Reichborn-Kjennerud, Ted and Ørstavik, Ragnhild E. 2014. Personality Disorders and Long-Term Sick Leave: A Population-Based Study of Young Adult Norwegian Twins. Twin Research and Human Genetics, Vol. 17, Issue. 01, p. 1.


    Kerridge, Bradley T. Saha, Tulshi D. and Hasin, Deborah S. 2014. DSM-IV schizotypal personality disorder: a taxometric analysis among individuals with and without substance use disorders in the general population. Mental Health and Substance Use, Vol. 7, Issue. 4, p. 446.


    Rosell, Daniel R. Futterman, Shira E. McMaster, Antonia and Siever, Larry J. 2014. Schizotypal Personality Disorder: A Current Review. Current Psychiatry Reports, Vol. 16, Issue. 7,


    Chemerinski, Eran Triebwasser, Joseph Roussos, Panos and Siever, Larry J. 2013. Schizotypal Personality Disorder. Journal of Personality Disorders, Vol. 27, Issue. 5, p. 652.


    Nilsen, Thomas S. Knudsen, Gun Peggy Gervin, Kristina Brandt, Ingunn Røysamb, Espen Tambs, Kristian Ørstavik, Ragnhild Lyle, Robert Reichborn-Kjennerud, Ted Magnus, Per and Harris, Jennifer R. 2013. The Norwegian Twin Registry from a Public Health Perspective: A Research Update. Twin Research and Human Genetics, Vol. 16, Issue. 01, p. 285.


    Triebwasser, Joseph Chemerinski, Eran Roussos, Panos and Siever, Larry J. 2013. Paranoid Personality Disorder. Journal of Personality Disorders, Vol. 27, Issue. 6, p. 795.


    Franke, B Faraone, S V Asherson, P Buitelaar, J Bau, C H D Ramos-Quiroga, J A Mick, E Grevet, E H Johansson, S Haavik, J Lesch, K-P Cormand, B and Reif, A 2012. The genetics of attention deficit/hyperactivity disorder in adults, a review. Molecular Psychiatry, Vol. 17, Issue. 10, p. 960.


    Gjerde, L. C. Czajkowski, N. Røysamb, E. Ørstavik, R. E. Knudsen, G. P. Østby, K. Torgersen, S. Myers, J. Kendler, K. S. and Reichborn-Kjennerud, T. 2012. The heritability of avoidant and dependent personality disorder assessed by personal interview and questionnaire. Acta Psychiatrica Scandinavica, Vol. 126, Issue. 6, p. 448.


    Guelfi, J.-D. 2012. Manuel de psychiatrie.


    South, Susan C. Reichborn-Kjennerud, Ted Eaton, Nicholas R. and Krueger, Robert F. 2012. Handbook of Psychology, Second Edition.


    Torgersen, Svenn Myers, John Reichborn-Kjennerud, Ted Røysamb, Espen Kubarych, Thomas S. and Kendler, Kenneth S. 2012. The Heritability of Cluster B Personality Disorders Assessed Both by Personal Interview and Questionnaire. Journal of Personality Disorders, p. 1.


    Torgersen, Svenn Myers, John Reichborn-Kjennerud, Ted Røysamb, Espen Kubarych, Thomas S. and Kendler, Kenneth S. 2012. The Heritability of Cluster B Personality Disorders Assessed Both by Personal Interview and Questionnaire. Journal of Personality Disorders, Vol. 26, Issue. 6, p. 848.


    Triebwasser, Joseph Chemerinski, Eran Roussos, Panos and Siever, Larry J. 2012. Schizoid Personality Disorder. Journal of Personality Disorders, Vol. 26, Issue. 6, p. 919.


    ×

The heritability of cluster A personality disorders assessed by both personal interview and questionnaire

  • KENNETH S. KENDLER (a1) (a2), JOHN MYERS (a1), SVENN TORGERSEN (a3), MICHAEL C. NEALE (a1) (a2) and TED REICHBORN-KJENNERUD (a4)
  • DOI: http://dx.doi.org/10.1017/S0033291706009755
  • Published online: 16 January 2007
Abstract

Background. Personality disorders (PDs) as assessed by questionnaires and personal interviews are heritable. However, we know neither how much unreliability of measurement impacts on heritability estimates nor whether the genetic and environmental risk factors assessed by these two methods are the same. We wish to know whether the same set of PD vulnerability factors are assessed by these two methods.

Method. A total of 3334 young adult twin pairs from the Norwegian Institute of Public Health Twin Panel (NIPHTP) completed a questionnaire containing 91 PD items. One to 6 years later, 1386 of these pairs were interviewed with the Structured Interview for DSM-IV Personality (SIDP-IV). Self-report items predicting interview results were selected by regression. Measurement models were fitted using Mx.

Results. In the best-fit models, the latent liabilities to paranoid personality disorder (PPD), schizoid personality disorder (SPD) and schizotypal personality disorder (STPD) were all highly heritable with no evidence of shared environmental effects. For PPD and STPD, only unique environmental effects were specific to the interview measure whereas both environmental and genetic effects were found to be specific to the questionnaire assessment. For SPD, the best-fit model contained genetic and environmental effects specific to both forms of assessment.

Conclusions. The latent liabilities to the cluster A PDs are highly heritable but are assessed by current methods with only moderate reliability. The personal interviews assessed the genetic risk for the latent trait with excellent specificity for PPD and STPD and good specificity for SPD. However, for all three PDs, the questionnaires were less specific, also indexing an independent set of genetic risk factors.

Copyright
Corresponding author
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University Medical School, Box 980126, 800 E. Leigh Street, Room 1-123, Richmond, VA 23298-0126, USA. (Email: kendler@vcu.edu)
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×