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Is obesity related to the type of dietary fatty acids? An ecological study

  • Nadiah Moussavi (a1), Victor Gavino (a1) and Olivier Receveur (a1)
  • DOI:
  • Published online: 01 November 2008

Animal studies and a few clinical trials lend credibility to the hypothesis that not all types of fatty acids carry the same potential for weight gain. Only a few epidemiological studies concerning this issue are currently available and results are conflicting.


The purpose of the present ecological study was to test the existence of an association between obesity prevalence and the types of fat available in 168 countries.


Data on the prevalence of obesity (BMI ≥ 30 kg/m2) for women over 15 years of age were obtained from the WHO Global InfoBase. Food balance sheets for the years 1998 to 2002 were obtained from the FAOSTAT database. Five-year means for energy, total fat, MUFA, PUFA, SFA and ‘other fat’ per capita were calculated, with their standard deviations, for each country. Bivariate correlations and a multiple linear regression model were used to test for the association between prevalence of obesity and types of fat available in these countries.


Not surprisingly, dietary energy supply, SFA, PUFA and ‘other fat’ were positively associated with the prevalence of obesity. We also found, however, a strong negative association between MUFA availability and obesity prevalence (β = −0·68, P < 0·0001).


Populations with a lower prevalence of obesity seem to consume a greater amount of MUFA. Considering the partial correlations between variables, our results suggest that in countries with higher obesity prevalence, it is the shift from MUFA to PUFA that particularly appears to be associated with the risk of obesity.

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1.GA Bray , S Paeratakul & BM Popkin (2004) Dietary fat and obesity: a review of animal, clinical and epidemiological studies. Physiol Behav 83, 549555.

4.C Pedone , S Urbinati , MG Pallotti & G Pinelle (2005) Cardiovascular disease: expected and unexpected relationship. Monaldi Arch Chest Dis 64, 3841.

5.EA Lew & L Garfinkel (1979) Variation in mortality by weight among 750 000 men and women. J Chronic Dis 32, 563576.

6.SD Poppitt & AM Prentice (1996) Energy density and its role in the control of food intake: evidence from metabolic and community studies. Appetite 26, 153174.

8.P Jones & DA Schoeller (1988) Polyunsaturated:saturated ratio of diet fat influences energy substrate utilization in the human. Metabolism 37, 145151.

12.JC Peters , BN Holcombe , LK Hiller & DR Webb (1991) Absorption and caloric value in adult humans. J Am Coll Toxicol 10, 357367.

16.H Schröder (2007) Protective mechanisms of the Mediterranean diet in obesity and type 2 diabetes. J Nutr Biochem 18, 149160.

19.P Flachs , O Horakova , P Brauner , M Rossmeisl , P Pecina & Hal Franssen-van (2005) Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce β-oxidation in white fat. Diabetologia 48, 23652375.

21.CJ Lovejoy , RS Smith , MC Champagne , MM Most , M Lefevre , PJ DeLany , MY Denkins , CJ Rood , J Veldhuis & AG Bray (2002) Effects of diets enriched in saturated (palmitic), monounsaturated (oleic), or trans (elaidic) fatty acids on insulin sensitivity and substrate oxidation in healthy adults. Diabetes Care 25, 12831288.

23.E Doucet , N Alméras , MD White , JP Despres , C Bouchard & A Tremblay (1998) Dietary fat composition and human adiposity. Eur J Clin Nutr 52, 26.

27.EJ Brunner , H Wunsuch & MG Marmot (2001) What is an optimal diet? Relationship of macronutrient intake to obesity, glucose tolerance, lipoprotein levels and the metabolic syndrome in the Whitehall II study. Int J Obes Relat Metab Disord 25, 4553.

28.J Sundstrom , L Lars , V Bengt , A Bertil , A Antti & L Hans (2001) Dyslipidemia and an unfavourable fatty acid profile predict left ventricular hypertrophy 20 years later. Circulation 103, 836841.

29.M Bes-Rastrollo , A Sanchez-Villegas , C de la Fuente , J de Irala , JA Martinez & MA Martinez-Gonzalez (2006) Olive oil consumption and weight change: the SUN prospective cohort study. Lipids 41, 249256.

35.DB Panagiotakos , C Chrysohoou , C Pitsavos & C Stefanadis (2006) Association between the prevalence of obesity and adherence to the Mediterranean diet: the ATTICA study. Nutrition 22, 449456.

36.A Trichopoulou , C Gnardellis , V Benetou , P Lagiou , C Bamia & D Trichopoulos (2002) Lipid, protein and carbohydrate intake in relation to body mass index. Eur J Clin Nutr 56, 3743.

42.C Bouchard , JP Despres & P Mauriege (1993) Genetic and nongenetic determinants of regional fat distribution. Endocrinol Rev 14, 7293.

43.M Guzman , J Lo Verme , J Fu , F Oveisi , C Blazquez & D Piomelli (2004) Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor α (PPAR-α). J Biol Chem 279, 2784927854.

44.N Tsunoda , S Ikemoto , M Takahashi , K Maruyama , H Watanabe , N Goto & O Ezaki (1998) High-monounsaturated fat diet-induced obesity and diabetes in C57BL/6J mice. Metabolism 47, 724730.

46.G Ailhaud , F Massiera , P Weill , P Legrand , JM Alessandri & P Guesnet (2006) Temporal changes in dietary fats: role of n-6 polyunsaturated fatty acids in excessive adipose tissue development and relationship to obesity. Prog Lipid Res 45, 203236.

47.TA Sanders (2001) Olive oil and the Mediterranean diet. Int J Vitam Nutr Res 71, 179184.

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Public Health Nutrition
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