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Akathisia: Prevalence and Associated Dysphoria in an In-patient Population with Chronic Schizophrenia

  • Simon M. Halstead (a1), Thomas R. E. Barnes (a2) and Jeremy C. Speller (a3)
Abstract

In a sample of 120 long-stay in-patients who fulfilled DSM–III–R criteria for schizophrenia, chronic akathisia and pseudoakathisia were relatively common, with prevalence figures of 24% and 18%, respectively. Compared with patients without evidence of chronic akathisia, those patients with the condition were significantly younger, were receiving significantly higher doses of antipsychotic medication, and were more likely to be receiving a depot antipsychotic. Patients who experienced the characteristic inner restlessness and compulsion to move of akathisia also reported marked symptoms of dysphoria, namely tension, panic, irritability and impatience. The findings support the suggestion that dysphoric mood is an important feature of akathisia. Male patients appeared to be at an increased risk of pseudoakathisia. No significant relation was found between chronic akathisia and tardive dyskinesia, although there was a trend for trunk and limb dyskinesia to be commonest in patients with chronic akathisia while orofacial dyskinesia was most frequently observed in those with pseudoakathisia. Akathisia may mask the movements of tardive dyskinesia in the lower limb. There was no evidence that akathisia was associated with positive or negative symptoms of schizophrenia nor with depression.

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References
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American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd edn, revised) (DSM–III–R). Washington, DC: APP.
Andreasen N. C. (1989) The Scale for the Assessment of Negative Symptoms (SANS): Conceptual and theoretical foundations. British Journal of Psychiatry, 155 (suppl. 7), 4952.
Baldessarini R. J. (1978) Chemotherapy. In The Harvard Guide to Modern Psychiatry (ed. A. M. Nicholi). Cambridge, Mass.: Harvard University Press.
Barnes T. R. E. (1989) A rating scale for drug-induced akathisia. British Journal of Psychiatry, 154, 672676.
Barnes T. R. E. (1990) Movement disorder associated with antipsychotic drugs: the tardive syndromes. International Review of Psychiatry, 2, 243254.
Barnes T. R. E. & Braude W. M. (1985) Akathisia variants and tardive dyskinesia. Archives of General Psychiatry, 42, 874878.
Barnes T. R. E., Halstead S. M. & Little P. W. A. (1992) Relationship between iron status and chronic akathisia in an in-patient population with chronic schizophrenia. British Journal of Psychiatry, 161, 791796.
Barnes T. R. E., & Trauer T. (1982) Reliability and validity of a tardive dyskinesia videotape rating technique. British Journal of Psychiatry, 140, 508515.
Braude W. M., Barnes T. R. E. & Gore S. M. (1983) Clinical characteristics of akathisia. A systematic investigation of acute psychiatric inpatient admissions. British Journal of Psychiatry, 143, 139150.
Davis J. M. (1976) Comparative doses and costs of antipsychotic medication. Archives of General Psychiatry, 33, 858861.
Drake R. E. & Ehrlich J. (1985) Suicide attempts associated with akathisia. American Journal of Psychiatry, 142, 499501.
Ekbom K. A. (1960) Restless legs syndrome. Neurology, 10, 868873.
Gibb W. R. G. & Lees A. J. (1986) The clinical phenomenon of akathisia. Journal of Neurology, Neurosurgery and Psychiatry, 49, 861866.
Kekich W. A. (1978) Violence as a manifestation of akathisia. Journal of the American Medical Association, 240, 2185.
Krawiecka M., Goldberg D. & Vaughan M. (1977) A standardised psychiatric assessment scale for rating chronic psychotic patients. Acta Psychiatrica Scandinavica, 55, 299308.
Kumar B. B. (1979) An unusual case of akathisia. American Journal of Psychiatry, 136, 1088.
Marder S. R., Van Putten T., Wirshing W. C., et al (1991) Subjective experiences of extrapyramidal side-effects in schizophrenia. In Biological Psychiatry (ed. G. Racagni et al). Amsterdam: Elsevier Science.
Munetz M. R. & Cornes C. L. (1982) Akathisia, pseudoakathisia and tardive dyskinesia. Comprehensive Psychiatry, 23, 345352.
Rey M.-J., Schulz P., Costa C., et al (1989) Guidelines for the dosage of neuroleptics. I: Chlorpromazine equivalents of orally administered neuroleptics. International Clinical Psychopharmacology, 4, 95104.
Schulte J. R. (1985) Homicide and suicide associated with akathisia and haloperidol. American Journal of Forensic Psychiatry, 6, 37.
Shaw E. D., Mann J. J., Weiden P. J., et al (1986) A case of suicidal and homicidal ideation and akathisia in a double-blind neuroleptic crossover study. Journal of Clinical Psychopharmacology, 6, 196197.
Shear K., Frances A. & Weiden P. (1983) Suicide associated with akathisia and depot fluphenazine treatment. Journal of Clinical Psychopharmacology, 3, 235236.
Simpson G. M. & Angus J. W. S. (1970) A rating scale for extrapyramidal side-effects. Acta Psychiatrica Scandinavica, 212 (suppl. 44), 1119.
Snaith R. P., Bridge G. W. K. & Hamilton M. (1976) The Leeds scales for the self-rating of anxiety of depression. British Journal of Psychiatry, 128, 156165.
Van Putten T. (1974) Why do schizophrenic patients refuse to take their drugs? Archives of General Psychiatry, 31, 6772.
Van Putten T., Mutalipassi L. R. & Malkin M. D. (1974) Phenothiazine induced decompensation. Archives of General Psychiatry, 30, 102105.
Weiden P. (1985) Akathisia from prochlorperazine Getter). Journal of the American Medical Association, 253, 635.
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The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
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Akathisia: Prevalence and Associated Dysphoria in an In-patient Population with Chronic Schizophrenia

  • Simon M. Halstead (a1), Thomas R. E. Barnes (a2) and Jeremy C. Speller (a3)
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