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Antidepressant drugs and sexual dysfunction

  • David S. Baldwin (a1) and Thomas Foong (a2)
Summary

Depressive symptoms and depressive illness are associated with impairments in sexual function and satisfaction but the findings of randomised placebo-controlled trials demonstrate that antidepressant drugs can be associated with the development or worsening of sexual dysfunction. Sexual difficulties during antidepressant treatment often resolve as depression lifts but may persist over long periods, and can reduce self-esteem and affect mood and relationships adversely. Sexual dysfunction during antidepressant treatment is typically associated with many possible causes, but the risk of dysfunction varies with differing antidepressants, and should be considered when selecting an antidepressant.

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Copyright
Corresponding author
David S. Baldwin, DM, FRCPsych, University Department of Psychiatry, College Keep, 4-12 Terminus Terrace, Southampton SO14 3DT, UK. Email: dsb1@soton.ac.uk
Footnotes
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This editorial is based on a talk given during the International Congress of the Royal College of Psychiatrists, Liverpool, 10-13 July 2012.

Declaration of interest

On behalf of his employer, D.S.B. has held research grants from Bristol-Myers Squibb, Cephalon, Eli Lilly, GlaxoSmithKline, H. Lundbeck A/S, Pierre Fabre, Pfizer, Roche, and Vernalis. He has served on advisory boards hosted by AstraZeneca, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, Grunenthal, H. Lundbeck A/S, Pierre Fabre, and Pfizer.

Footnotes
References
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The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
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Antidepressant drugs and sexual dysfunction

  • David S. Baldwin (a1) and Thomas Foong (a2)
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