Craddock, N, Owen, MJ. The beginning of the end for the Kraepelinian
dichotomy. Br J Psychiatry
2005; 186: 364–6.
Lichtenstein, P, Yip, BH, Björk, C, Pawitan, Y, Cannon, TD, Sullivan, PF, et al. Common genetic determinants of schizophrenia
and bipolar disorder in Swedish families: a population-based
2009; 373: 234–9.
Owen, MJ, Craddock, N. Diagnosis of functional psychoses: time to face the
2009; 373: 190–1.
O'Donovan, MC, Craddock, N, Norton, N, Williams, H, Peirce, T, Moskvina, V, et al. Identification of loci associated with
schizophrenia by genome-wide association and follow-up.
2008; 40: 1053–5.
Green, EK, Grozeva, D, Jones, I, Jones, L, Kirov, G, Caesar, S, et al. The bipolar disorder risk allele at CACNA1C
also confers risk of recurrent major depression and of
schizophrenia. Mol Psychiatry
Ferreira, MA, O'Donovan, MC, Meng, YA, Jones, IR, Ruderfer, DM, Jones, L, et al. Collaborative genome-wide association
analysis supports a role for ANK3 and CACNA1C in bipolar
disorder. Nat Genet
2008; 40: 1056–8.
Moskvina, V, Craddock, N, Holmans, P, Nikolov, I, Pahwa, JS, Green, E, et al. Gene-wide analyses of genome-wide association
data sets: evidence for multiple common risk alleles for schizophrenia
and bipolar disorder and for overlap in genetic risk.
2009; 14: 252–60.
The International Schizophrenia Consortium.
Common polygenic variation contributes to risk of
schizophrenia and bipolar disorder.
2009; 460: 748–52.
McCarroll, SA, Altshuler, DM. Copy-number variation and association studies of
human disease. Nat Genet
2007; 39 (suppl 7):
Weiss, LA, Shen, Y, Korn, JM, Arking, DE, Miller, DT, Fossdal, R, et al. Association between microdeletion and
microduplication at 16p11.2 and autism. N Engl J
2008; 358: 667–75.
Walsh, T, McClellan, JM, McCarthy, SE, Addington, AM, Pierce, SB, Cooper, GM, et al. Rare structural variants disrupt multiple
genes in neurodevelopmental pathways in schizophrenia.
2008; 320: 539–43.
Stefansson, H, Rujescu, D, Cichon, S, Pietiläinen, OP, Ingason, A, Steinberg, S, et al. Large recurrent microdeletions associated
with schizophrenia. Nature
2008; 455: 232–6.
The International Schizophrenia Consortium.
Rare chromosomal deletions and duplications increase risk
of schizophrenia. Nature
2008; 455: 237–41.
Kirov, G, Grozeva, D, Norton, N, Ivanov, D, Mantripragada, KK, Holmans, P, et al. Support for the involvement of large copy
number variants in the pathogenesis of schizophrenia.
Hum Mol Genet
2009; 18: 1497–503.
Pagnamenta, AT, Wing, K, Akha, ES, Knight, SJ, Bölte, S, Schmötzer, G, et al. A 15q13.3 microdeletion segregating with
autism. Eur J Hum Genet
2008; 17: 687–92.
Kirov, G, Rujescu, D, Ingason, A, Collier, DA, O'Donovan, MC, Owen, MJ. Neurexin 1 (NRXN1) deletions in
schizophrenia. Schizophr Bull
2009; 35: 851–4.
Burbach, JP, van der Zwaag, B. Contact in the genetics of autism and
schizophrenia. Trends Neurosci
Zhang, D, Cheng, L, Qian, Y, Alliey-Rodriguez, N, Kelsoe, JR, Greenwood, T, et al. Singleton deletions throughout the genome
increase risk of bipolar disorder. Mol
2008; 14: 376–80.
McCarthy, SE, Makarov, M, Kirov, G, Addington, AM, McClellan, J, Yoon, S, et al. Microduplications of 16p11.2 are associated
with schizophrenia. Nat Genet
2009; 41: 1223–7.
Grozeva, D, Kirov, G, Ivanov, D. Rare copy number variants (CNVs): a point of rarity
in genetic risk for bipolar disorder and schizophrenia?
Arch Gen Psychiatry
Murray, RM, Sham, P, van Os, J, Zanelli, J, Cannon, M, McDonald, C. A developmental model for similarities and
dissimilarities between schizophrenia and bipolar
disorder. Schizophr Res
2004; 71: 405–16.
Hamshere, ML, Green, EK, Jones, IR, Jones, L, Moskvina, V, Kirov, G, et al. Genetic utility of broadly defined bipolar
schizoaffective disorder as a diagnostic concept.
Br J Psychiatry
2009; 195: 23–9.
Craddock, N, Jones, L, Jones, IR, Kirov, G, Green, EK, Grozeva, D, et al. Strong genetic evidence for a selective
influence of GABA(A) receptors on a component of the bipolar disorder
phenotype. Mol Psychiatry
Craddock, N, O'Donovan, MC, Owen, MJ. Psychosis genetics: modeling the relationship
between schizophrenia, bipolar disorder, and mixed (or ‘schizoaffective’)
psychoses. Schizophr Bull
2009; 35: 482–90.
Heckers, S. Is schizoaffective disorder a useful
Curr Psychiatry Rep
2009; 11: 332–7.
Craddock, N, Owen, MJ. Rethinking psychosis: the disadvantages of a
dichotomous classification now outweigh the advantages.
van Os, J, Kapur, S. Schizophrenia.
2009; 374: 635–45.
Bullmore, E, Sporns, O. Complex brain networks: graph theoretical analysis
of structural and functional systems. Nat Rev
2009; 10: 186–98.
Zielasek, J, Gaebel, W. Modern modularity and the road towards a modular
psychiatry. Eur Arch Psychiatry Clin
2008; 258 (suppl 5):
Kendler, KS. Reflections on the relationship between psychiatric
genetics and psychiatric nosology. Am J
2006; 163: 1138–46.
Cross-Disorder Phenotype Group of the Psychiatric GWAS
Consortium, Craddock, N, Kendler, K, Neale, M, Nurnberger, J, Purcell, S, et al. Dissecting the phenotype in genome-wide
association studies of psychiatric illness. Br J
2009; 195: 97–9.