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Major depression and its correlates in primary care settings in six countries: 9-month follow-up study

  • Marcelo Pio De Almeida Fleck (a1), Gregory Simon (a2), Helen Herrman (a3), Donald Bushnell (a4), Mona Martin (a4) and Donald Patrick (a5)...
Abstract
Background

Few published studies address depression outcomes in primary care from a cross-cultural perspective.

Aims

To define baseline factors associated with 9-month clinical outcome: across six countries.

Method

Adults meeting criteria for current major depression were recruited from primary care clinics in Australia, Brazil, Israel, Spain, Russia and the USA; 968 patients were assessed at the 9-month follow-up. Predictors of complete remission were examined using logistic regression with a hierarchical model.

Results

Rates of complete remission in the six sites ranged from 25% to 48%. Logistic regression using pooled data showed that education, key life events and the Quality of Life Depression Scale score at baseline were the final predictors of complete remission, adjusting for centres, socio-demographic data, severity of depression, comorbidity and general quality of life. Variation in predictors across sites was not statistically significant.

Conclusions

The two major findings of this study were the low proportion of people achieving complete remission at follow-up across the six sites, and that some baseline characteristics (education, Quality of Life Depression Scale score and key life events) are modest predictors of outcome in depression.

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Copyright
Corresponding author
Dr Marcelo Pio de Almeida Fleck, Departamento de Psiquiatria e Medicina Legal, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcellos 2350 4° andar, 90035-003 – Porto Alegre – RS, Brazil. E-mail: mfleck.voy@zaz.com.br
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Declaration of interest

None. See Appendix for details of the LIDO Group funding.

Footnotes
References
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The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
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Major depression and its correlates in primary care settings in six countries: 9-month follow-up study

  • Marcelo Pio De Almeida Fleck (a1), Gregory Simon (a2), Helen Herrman (a3), Donald Bushnell (a4), Mona Martin (a4) and Donald Patrick (a5)...
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