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Outcomes of an effectiveness trial of cognitive–behavioural intervention by mental health nurses in schizophrenia

  • Douglas Turkington (a1), David Kingdon (a2), Shanaya Rathod (a3), Katie Hammond (a4), Jeremy Pelton (a1) and Raj Mehta (a5)...
Abstract
Background

Little is known about the medium-term durability of cognitive–behavioural therapy (CBT) in a community sample of people with schizophrenia.

Aims

To investigate whether brief CBT produces clinically important outcomes in relation to recovery, symptom burden and readmission to hospital in people with schizophrenia at 1-year follow-up.

Method

Participants (336 of 422 randomised at baseline) were followed up at a mean of 388 days (s.d. =53) by raters masked to treatment allocation (CBT or usual care).

Results

At 1-year follow-up, participants who received CBT had significantly more insight (P=0.021) and significantly fewer negative symptoms (P=0.002). Brief therapy protected against depression with improving insight and against relapse; significantly reduced time spent in hospital for those who did relapse and delayed time to admission. It did not improve psychotic symptoms or occupational recovery, nor have a lasting effect on overall symptoms or depression at follow-up.

Conclusions

Mental health nurses should be trained in brief CBT for schizophrenia to supplement case management, family interventions and expert therapy for treatment resistance.

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Copyright
Corresponding author
Professor Douglas Turkington, School of Neurology, Neurosciences and Psychiatry, Royal Victoria Infirmary, Richardson Road, Newcastle upon Tyne NE1 4LP. Tel.: +44 (0) 191 2824842, email: douglas.turkington@ncl.ac.uk
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Declaration of interest

None. Trial funded by a research grant from Pfizer.

Footnotes
References
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  • ISSN: 0007-1250
  • EISSN: 1472-1465
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Outcomes of an effectiveness trial of cognitive–behavioural intervention by mental health nurses in schizophrenia

  • Douglas Turkington (a1), David Kingdon (a2), Shanaya Rathod (a3), Katie Hammond (a4), Jeremy Pelton (a1) and Raj Mehta (a5)...
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