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IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies

  • Nancy L. Pedersen (a1) (a2), Kaare Christensen (a3), Anna K. Dahl (a1) (a4), Deborah Finkel (a5), Carol E. Franz (a6), Margaret Gatz (a1) (a2), Briana N. Horwitz (a7), Boo Johansson (a8), Wendy Johnson (a9), William S. Kremen (a6) (a10), Michael J. Lyons (a11), Bo Malmberg (a4), Matt McGue (a3) (a12), Jenae M. Neiderhiser (a7), Inge Petersen (a3) and Chandra A. Reynolds (a13)...
Abstract

The Interplay of Genes and Environment across Multiple Studies (IGEMS) group is a consortium of eight longitudinal twin studies established to explore the nature of social context effects and gene-environment interplay in late-life functioning. The resulting analysis of the combined data from over 17,500 participants aged 25–102 at baseline (including nearly 2,600 monogygotic and 4,300 dizygotic twin pairs and over 1,700 family members) aims to understand why early life adversity, and social factors such as isolation and loneliness, are associated with diverse outcomes including mortality, physical functioning (health, functional ability), and psychological functioning (well-being, cognition), particularly in later life.

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Copyright
Corresponding author
address for correspondence: Nancy L. Pedersen, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE-171 77 Stockholm, Sweden. E-mail: Nancy.Pedersen@ki.se
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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

D. J. Bauer , & A. M. Hussong (2009). Psychometric approaches for developing commensurate measures across independent studies: Traditional and new models. Psychological Methods, 14, 101125.

J. T. Cacioppo , M. E. Hughes , L. J. Waite , L. C. Hawkley , & R. A. Thisted (2006). Loneliness as a specific risk factor for depressive symptoms: Cross-sectional and longitudinal analyses. Psychology and Aging, 21, 140151.

K. Christensen , G. Doblhammer , R. Rau , & J. W. Vaupel (2009). Ageing populations: The challenges ahead. Lancet, 374, 11961208.

K. Christensen , N. V. Holm , M. McGue , L. Corder , & J. W. Vaupel (1999). A Danish population-based twin study on general health in the elderly. Journal of Aging and Health, 11, 4964.

K. Christensen , M. McGue , I. Petersen , B. Jeune , & J. W. Vaupel (2008). Exceptional longevity does not result in excessive levels of disability. Proceedings of the National Academy of Sciences of the United States of America, 105, 1327413279.

L. Christiansen , H. Frederiksen , K. Schousboe , A. Skytthe , N. von Wurmb-Schwark , K. Christensen , & K. Kyvik (2003). Age- and sex-differences in the validity of questionnaire-based zygosity in twins. Twin Research, 6, 275278.

S. Cohen (2004). Social relationships and health. American Psychologist, 59, 676684.

S. Cohen , & D. Janicki-Deverts (2009). Can we improve our physical health by altering our social networks? Perspectives on Psychological Science, 4, 375378.

P. J. Curran , & A. M. Hussong (2009). Integrative data analysis: The simultaneous analysis of multiple data sets. Psychological Methods, 14, 81100.

D. Finkel , & M. McGue (1993). The origins of individual differences in memory among the elderly: A behavior genetic analysis. Psychology and Aging, 8, 527537.

D. Finkel , & N. L. Pedersen (2004). Processing speed and longitudinal trajectories of change for cognitive abilities: The Swedish Adoption/Twin Study of Aging. Aging, Neuropsychology, and Cognition. Special Issue: Longitudinal Studies Of Cognitive Aging, 11, 325345.

M. Gatz , N. L. Pedersen , R. Plomin , J. R. Nesselroade , & G. E. McClearn (1992). Importance of shared genes and shared environments for symptoms of depression in older adults. Journal of Abnormal Psychology, 101, 701708.

L. C. Hawkley , & J. T. Cacioppo (2003). Loneliness and pathways to disease. Brain, Behavior, and Immunity, 17, S98S105.

W. Johnson , & R. F. Krueger (2005a). Genetic effects on physical health: Lower at higher income levels. Behavior Genetics, 35, 579590.

W. Johnson , & R. F. Krueger (2005b). Higher perceived life control decreases genetic variance in physical health: Evidence from a national twin study. Journal of Personality and Social Psychology, 88, 165173.

G. E. McClearn , B. Johansson , S. Berg , N. L. Pedersen , F. Ahern , S. A. Petrill , & R. Plomin (1997). Substantial genetic influence on cognitive abilities in twins 80 or more years old. Science, 276, 15601563.

M. McGue , & K. Christensen (1997). Genetic and environmental contributions to depression symptomatology: Evidence from Danish twins 75 years of age and older. Journal of Abnormal Psychology, 106, 439448.

M. McGue , B. Hirsch , & D. T. Lykken (1993). Age and the self-perception of ability: A twin study analysis. Psychology and Aging, 8, 7280.

M. Osler , M. McGue , R. Lund , & K. Christensen (2008). Marital status and twins’ health and behavior: An analysis of middle-aged Danish twins. Psychosomatic Medicine, 70, 482487.

I. P. F. Owens (2002). Ecology and evolution: Sex differences in mortality rate. Science, 297, 20082009.

L. S. Radloff (1977). The CES-D Scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1, 385401.

R. Rosenthal (1991). Meta-analytic procedures for social research (Rev. ed.). Newbury Park, CA: Sage.

R. Rosenthal , & M. R. DiMatteo (2001). Meta-analysis: Recent developments in quantitative methods for literature reviews. Annual Review of Psychology, 52, 5982.

C. A. Velozo , K. L. Byers , Y. Wang , & B. R. Joseph (2007). Translating measures across the continuum of care: Using Rasch analysis to create a crosswalk between the Functional Independence Measure and the Minimum Data Set. Journal of Rehabilitation Research and Development, 44, 467478.

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Twin Research and Human Genetics
  • ISSN: 1832-4274
  • EISSN: 1839-2628
  • URL: /core/journals/twin-research-and-human-genetics
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