Phenmedipham was registered for use at 1.1 to 1.7 kg ai/ha in 1970 and desmedipham at 1.1 to 1.4 kg ai/ha in 1974 for postemergence control of broadleaf weeds in sugarbeet. Phenmedipham was sold from 1970 through 1981 and desmedipham plus phenmedipham (1:1), as a premixed product, has been sold since 1982. Development of multiple applications of reduced rates began in 1972 primarily to reduce sugarbeet injury. The technique was promoted to farmers after 1976. Ahalf-rate of phenmedipham and/or desmedipham applied twice at a 5- to 7-d interval controlled weeds better and caused less sugarbeet injury than a single full-rate application, and allowed application to smaller than four-leaf sugarbeet. Suggested sugarbeet size for the first application changed from 4-leaf in 1970 to cotyledon to two-leaf in 1992. Earlier application to more susceptible small weeds allowed a further rate reduction. The use of soil-applied herbicides prior to phenmedipham and/or desmedipham increased weed control and sugarbeet injury. Application to small weeds and sugarbeet by air or by ground sprayers at spray pressures over 1040 kPa controlled weeds better and injured sugarbeet more than when applied by ground sprayers at 280 kPa. Desmedipham and phenmedipham rates presently are adjusted for sugarbeet size, application method, soil-applied herbicide, and environment. The suggested initial application rate of phenmedipham and/or desmedipham in 1992 was 0.13 to 0.28 kg/ha as compared with 1.1 to 1.7 kg/ha in 1970. A typical rate of desmedipham or desmedipham plus phenmedipham applied in 1992, including multiple application, was approximately 0.7 kg/ha less than typical rates from 1970 through 1977.