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Relationships between Environmental Dependency and Closing-in in Patients with Fronto-temporal Dementia

Published online by Cambridge University Press:  17 November 2014

Dario Grossi ,
Natascia De Lucia ,
Graziella Milan  and
Luigi Trojano
Dario Grossi
Affiliation:
Neuropsychology Lab, Department of Psychology, Second University of Naples, Caserta, Italy
Natascia De Lucia
Affiliation:
Neuropsychology Lab, Department of Psychology, Second University of Naples, Caserta, Italy
Graziella Milan
Affiliation:
Geriatric Centre Frullone ASL NA/1, Naples, Italy
Luigi Trojano*
Affiliation:
Neuropsychology Lab, Department of Psychology, Second University of Naples, Caserta, Italy Salvatore Maugeri Foundation, IRCCS, Rehabilitation Institute of Telese Terme (BN), Italy
*
Correspondence and reprint requests to: Luigi Trojano, Neuropsychology Lab, Department of Psychology, Second University of Naples, Viale Ellittico 31, 81100 Caserta, Italy. E-mail: luigi.trojano@unina2.it
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Abstract

Environmental dependency (ED) phenomena, including utilization behavior and imitation behavior, are clinical manifestations typically observed in patients with the behavioral variant of fronto-temporal dementia (bvFTD), who may also show the closing-in (CI) phenomenon. Here, we explored the neuropsychological correlates of ED and CI in bvFTD, and the association of ED with CI to clarify the mechanisms underlying these clinical manifestations. Thirty-one bvFTD patients underwent a wide cognitive assessment in addition to special tasks to detect occurrence of CI and ED phenomena. Both ED and CI phenomena were present in more than half of the sample. Logistic regression analyses revealed that both ED and CI phenomena were significantly associated with poor scores on frontal neuropsychological tests. Although ED and CI often co-occurred, 3/12 patients with CI did not show ED, and 5/18 patients with ED did not show CI. A logistic regression model showed that the presence of ED was not significantly associated to CI. CI and ED are associated to progressive derangement of frontal functions in bvFTD. However, specific frontal dysfunctions might explain the occurrence of either phenomenon in isolation. (JINS, 2015, 21, 1–7)

Keywords

Utilization behaviorImitation behaviorclosing-inFronto-temporal dementiaEnvironmental dependencyFrontal defects
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 21 , Issue 1 , January 2015 , pp. 1 - 7
Copyright
Copyright © The International Neuropsychological Society 2014 

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