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IgG1 variations in the colostrum of Holstein dairy cows

Published online by Cambridge University Press:  16 September 2015

Y. Le Cozler ,
R. Guatteo ,
E. Le Dréan ,
H. Turban ,
F. Leboeuf ,
K. Pecceu  and
J. Guinard-Flament
Y. Le Cozler*
Affiliation:
AGROCAMPUS-Ouest, UMR1348 Physiology, Environment and Genetics for Animal and Livestock Systems, 35000 Rennes, France INRA, UMR1348 Physiology, Environment and Genetics for Animal and Livestock Systems, 35590 St-Gilles, France
R. Guatteo
Affiliation:
LUNAM Université, Oniris, UMR BioEpAR, CS 40706, 44307 Nantes, France INRA, UMR1300 BioEpAR, CS 40706, 44307 Nantes, France
E. Le Dréan
Affiliation:
Institut en Santé Agro Environnement d’Ille-et-Vilaine, Rennes, 35270 Combourg, France
H. Turban
Affiliation:
Institut en Santé Agro Environnement d’Ille-et-Vilaine, Rennes, 35270 Combourg, France
F. Leboeuf
Affiliation:
MSD Santé Animale, 49071 Beaucouzé, France
K. Pecceu
Affiliation:
MSD Santé Animale, 49071 Beaucouzé, France
J. Guinard-Flament
Affiliation:
AGROCAMPUS-Ouest, UMR1348 Physiology, Environment and Genetics for Animal and Livestock Systems, 35000 Rennes, France INRA, UMR1348 Physiology, Environment and Genetics for Animal and Livestock Systems, 35590 St-Gilles, France
*
†E-mail: yannick.lecozler@agrocampus-ouest.fr
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Abstract

High-immune quality colostrum (IgG1 concentration ⩾50 g/l) is crucial for the health and development of the young calf. Studies on colostrum quality tend to focus on external factors such as breed, parity or dry period length, but few have focused on within-cow variations. Here we ran experiments to gain a deeper insight into within-cow variation in IgG1 concentrations in dairy cow colostrum. Trials were performed in an experimental farm, located in the Western part of France. Colostrum from each quarter and a composite sample (mix of four quarters) were concomitantly collected on 77 Holstein dairy cows just after calving to assess the influence of sample type on IgG1 concentrations. Variation in IgG1 concentrations during the first milking was studied on samples from nine cows collected every minute from the start of milking. Repeatability of colostral IgG1 concentration was estimated from 2009 and 2010 data on 16 healthy cows. IgG1 concentrations were tested using a radial immunodiffusion method. Sensitivity and specificity were similar regardless of sample type tested (individual quarter or composite milk). Mean average IgG1 concentration was 54.1 g/l in composite colostrum, and was significantly higher in hind quarter teats (56.2 g/l) than front quarter teats (53.1 g/l). Average IgG1 concentration did not change significantly during colostrum milking, and the variations observed (15% or less) were likely due to the laboratory method (CV 15%). IgG1 concentrations in dam colostrum increased slightly from 2009 to 2010 due to BW and parity effects. In 56% of cases, colostrum quality could have been assessed on either individual or composite colostrum samples collected at any time during the first milking without affecting the reliability of the measurement. However, in other cases, differences were significant enough to mean that estimates of average IgG1 concentration in colostrum from any one quarter would not be reliable. It is concluded that colostrum quality, from an IgG1 concentration point of view, could be assessed with a composite sample taken at any time during the first milking.

Keywords

dairy cowscalvescolostrumIgG1 variation
Type
Research Article
Information
animal , Volume 10 , Issue 2 , February 2016 , pp. 230 - 237
Copyright
© The Animal Consortium 2015 

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References

Baumrucker, CR, Burkett, AM, Magliaro-Macrina, AL and Dechow, CD 2010. Colostrogenesis: mass transfer of immunoglobulin G1 into colostrum. Journal of Dairy Science 93, 3031–3038.Google Scholar
Baumrucker, CR, Stark, A, Wellnitz, O, Dechow, C and Bruckmaier, RM 2014. Short communication: immunoglobulin variation in quarter-milked colostrum. Journal of Dairy Science 97, 3700–3706.Google Scholar
Conneely, M, Berry, DP, Sayers, R, Murphy, JP, Lorenz, I, Doherty, ML and Kennedy, E 2013. Factors associated with the concentration of immunoglobulin G in the colostrum of dairy cows. Animal 11, 1824–1832.Google Scholar
Conneely, M, Berry, DP, Murphy, JP, Lorenz, I, Doherty, ML and Kennedy, E 2014. Effect of feeding colostrum at different volumes and subsequent number of transition milk feeds on the serum immunoglobulin G concentration and health status of dairy calves. Journal of Dairy Science 97, 6991–7000.Google Scholar
Dardillat, J, Trillat, G and Larvor, P 1978. Colostrum immunoglobulin concentrations in cows: relationship with their calf mortality and with the colostrum quality of their female offspring. Annales de Recherches Vétérinaires 9, 375–384.Google Scholar
Foley, JA and Otterby, DE 1978. Availability, storage, treatment, composition, and feeding value of surplus colostrum: a review. Journal of Dairy Science 61, 1033–1060.CrossRefGoogle Scholar
Godden, S 2008. Colostrum management for dairy calves. Veterinary Clinics Food Animal Practice 24, 19–39.Google Scholar
Gomes, V, Madureira, KM, Soriano, S, Melville, AM, Della Libera, P, Garcia Blagitz, M and Benesi, FJ 2011. Factors affecting immunoglobulin concentration in colostrums of healthy Holstein cows immediately after delivery. Pesquisa Veterinaria Brasileira 31, 53–56.Google Scholar
Gulliksen, SM, Lie, KI, Solverod, L and Osteras, O 2008. Risk factors associated with colostrum quality in Norwegian Dairy cows. Journal of Dairy Science 91, 704–712.Google Scholar
Guinard-Flament, J, Michalski, MC and Rulquin, H 2001. Evolution des taux butyreux et du diamètre des globules gras au cours de la traite chez la vache laitière. Rencontres autour des Recherches sur les Ruminants 8, 96.Google Scholar
Hostetler, D, Douglas, VL, Tyler, J, Holle, J and Steevens, B 2003. Immunoglobulin G concentrations in temporal fractions of first milking colostrum in dairy Cows. International Journal of Applied Research in Veterinary Medicine 1, 168–171.Google Scholar
INRA 1989. Ruminant nutrition. Recommended allowances and feed tables. Chapter 2: Energy: the feed unit systems, 73–92. In John Libbey Eurotext (ad. R. Jarrige), 395pp. INRA, London, UK.Google Scholar
INRA 2007. Alimentation des bovins, ovins et caprins. Besoin des animaux – valeurs des aliments. Chapitre 2: alimentation des vaches laitières. QUAE éditions, Versailles, France, 310pp.Google Scholar
Jaster, EH 2005. Evaluation of quality, quantity, and timing of colostrum feeding on immunoglobulin G1 absorption in Jersey calves. Journal of Dairy Science 88, 296–302.Google Scholar
Jégou, V, Porhiel, JY, Brunschwig, P and Jouanne, D 2006. Mortalité des veaux d’élevage en Bretagne: facteurs de risque de mortalité dans 80 élevages bretons. Rencontres autour des Recherches sur les Ruminants 13, 423–426.Google Scholar
Korhonen, H, Marnilla, P and Gill, HS 2000. Milk immunoglobulins and complement factors. British Journal of Nutrition 84, S75–S80.CrossRefGoogle ScholarPubMed
Levieux, D and Ollier, A 1999. Bovine immunoglobulin G, β-lactalbumin and serum albumin in colostrum and milk during the early post partum period. Journal of Dairy Research 66, 421–430.Google Scholar
Mancini, G, Carbonara, AO and Heremans, J 1965. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunology 2, 207–285.Google Scholar
Maunsell, FP, Morin, DE, Constable, PD, Hurley, WL, McCoy, GC, Kakoma, I and Isaacson, RE 1998. Effect of mastitis on the volume and composition of colostrums produced by Holstein cows. Journal of Dairy Science 81, 1291–1299.Google Scholar
Muller, LD and Ellinger, DK 1981. Colostral immunoglobulin concentrations among breeds of dairy cattle. Journal of Dairy Science 64, 1727–1730.CrossRefGoogle ScholarPubMed
Norman, LM, Hohenboken, WD and Kelley, KW 1981. Genetic differences in concentration of immunoglobulins G1 and M in serum and colostrum of cows and in serum of neonatal calves. Journal of Animal Science 53, 1465–1472.Google Scholar
Park, SC and Jacobson, NL 1993. The mammary gland and lactation. In Dukes physiology of domestic animals (ed MJ Swenson and WO Reece), pp. 711–722. Cmstock Publishing Company Inc., New York, USA.Google Scholar
Pritchett, LC, Gay, CC, Besser, TE and Hancock, DD 1991. Management and production factors influencing immunoglobulin G1 concentration in colostrums from Holstein cows. Journal of Dairy Science 74, 2336–2341.Google Scholar
Quigley, JD, Lago, A, Chapman, C, Erickson, P and Polo, J 2013. Evaluation of the Brix refractometer to estimate immunoglobulin G concentration in bovine colostrum. Journal of Dairy Science 96, 1148–1155.CrossRefGoogle ScholarPubMed
Robinson, PH, Moorby, JM and Gisi, DD 2009. Colostrum production by primiparous and multiparous Holstein dairy cows and its usefulness as an estimator of full lactation yield. Livestock Science 125, 323–325.Google Scholar
Sordillo, LM and Nickerson, SC 1988. Quantification and immunoglobulin classification of plasma cells in nonlactating bovine mammary tissue. Journal of Animal Science 71, 84–91.Google Scholar
Tyler, JW, Steevens, BJ, Hostetler, DE, Holle, JM and Denbigh, JL 1999. Colostral IgG concentrations in Holstein and Guernsey cows. American Journal of Veterinary Research 60, 1136–1139.Google Scholar
Venables, WN and Smith, DM 2010. The R Development Core Team. An introduction to R. Notes on R: programming environment for data analysis and graphics. R Development Core Team, Vienna, Austria.Google Scholar
Weaver, DM, Tyler, JW, VanMetre, DC, Hostetler, DE and Barrington, GM 2000. Passive transfer of colostral immunoglobulins in calves. Journal of Veterinary Internal Medicine 14, 569–577.Google Scholar