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Atypical Local Interference Affects Global Processing in Children with Neurofibromatosis Type 1

Published online by Cambridge University Press:  11 April 2017

Jonathan M. Payne ,
Melanie A. Porter ,
Samantha Bzishvili  and
Kathryn N. North
Jonathan M. Payne*
Affiliation:
Murdoch Childrens Research Institute, The Royal Children’s Hospital, Australia Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Australia
Melanie A. Porter
Affiliation:
Department of Psychology, Centre for Atypical Neurodevelopment, Macquarie University, Australia
Samantha Bzishvili
Affiliation:
Department of Psychology, Centre for Atypical Neurodevelopment, Macquarie University, Australia
Kathryn N. North
Affiliation:
Murdoch Childrens Research Institute, The Royal Children’s Hospital, Australia Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Australia
*
Correspondence and reprint requests to: Jonathan M. Payne. Murdoch Childrens Research Institute, Royal Children’s Hospital, Flemington Road, Parkville VIC 3052 Australia. E-mail: jonathan.payne@mcri.edu.au
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Abstract

Objectives: To examine hierarchical visuospatial processing in children with neurofibromatosis type 1 (NF1), a single gene disorder associated with visuospatial impairments, attention deficits, and executive dysfunction. Methods: We used a modified Navon paradigm consisting of a large “global” shape composed of smaller “local” shapes that were either congruent (same) or incongruent (different) to the global shape. Participants were instructed to name either the global or local shape within a block. Reaction times, interference ratios, and error rates of children with NF1 (n=30) and typically developing controls (n=24) were compared. Results: Typically developing participants demonstrated the expected global processing bias evidenced by a vulnerability to global interference when naming local stimuli without a cost of congruence when naming global stimuli. NF1 participants, however, experienced significant interference from the unattended level when naming both local and global levels of the stimuli. Conclusions: Findings suggest that children with NF1 do not demonstrate the typical human bias of processing visual information from a global perspective. (JINS, 2017, 23, 446–450)

Keywords

Visuospatial processingNavon stimuliLocal-global processingLocal interferenceSelective attentionPerception
Type
Brief Communication
Information
Journal of the International Neuropsychological Society , Volume 23 , Issue 5 , May 2017 , pp. 446 - 450
Copyright
Copyright © The International Neuropsychological Society 2017 

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