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Chapter 32 - Cardiac Ischaemia

from Section 3 - Cardiovascular Physiology

Published online by Cambridge University Press:  31 July 2019

David Chambers ,
Christopher Huang  and
Gareth Matthews
David Chambers
Affiliation:
Salford Royal NHS Foundation Trust
Christopher Huang
Affiliation:
University of Cambridge
Gareth Matthews
Affiliation:
University of Cambridge
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Summary

The oxygen extraction ratio (OER) is the ratio of oxygen consumption, V̇O2, to oxygen delivery, ḊO2 (see Chapter 17). At around 60%, the OER of the heart is near maximal. This is in contrast to the lower OERs of the liver (around 50%), the kidney (around 15%) and skeletal muscle (between 10% and 100% depending on activity).

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Basic Physiology for Anaesthetists , pp. 141 - 144
Publisher: Cambridge University Press
Print publication year: 2019

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References

Further reading

Kaski, J. C., Hausenloy, D. J., Gersh, B. J., Yellon, D. M. (Eds.). Management of Myocardial Reperfusion Injury. Berlin, Springer, 2012.CrossRefGoogle Scholar
Pinski, M. R., Artigas, A., Dhainaut, J. F.. Coronary Circulation and Myocardial Ischemia. New York, Springer-Verlag, 2002.Google Scholar
van Lier, F., Wesdorp, F. H. I. M., Liem, V. G. B., et al. Association between postoperative mean arterial blood pressure and myocardial injury after non-cardiac surgery. Br J Anaesth 2018; 120(1): 77–83.CrossRefGoogle Scholar
Chapman, A. R., Adamson, P. D., Mills, N. L.. Assessment and classification of patients with myocardial injury and infarction in clinical practice. Heart 2017; 103: 10–18.CrossRefGoogle ScholarPubMed
Ekeloef, S., Alamili, M., Devereaux, P. J., et al. Troponin elevations after non-cardiac, non-vascular surgery are predictive of major adverse cardiac events and mortality: a systematic review and meta-analysis. Br J Anaesth 2016; 117(5): 559–68.CrossRefGoogle ScholarPubMed
Zhang, Z.-M., Rautaharju, P. M., Prineas, R. J., et al. Race and sex differences in the incidence and prognostic significance of silent myocardial infarction in the Atherosclerosis Risk In Communities (ARIC) study. Circulation 2016; 133(22): 2141–8.CrossRefGoogle ScholarPubMed
Foreman, R. D., Garrett, K. M., Blair, R. W.. Mechanisms of cardiac pain. Compr Physiol 2015; 5: 929–60.CrossRefGoogle ScholarPubMed
Loveridge, R., Schroeder, F.. Anaesthetic preconditioning. Continuing Educ Anaesth Crit Care Pain 2010; 10(2): 38–42.CrossRefGoogle Scholar

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