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Chapter 36 - Thyroid Disease in Pregnancy

from Section 4 - Maternal Medicine

Published online by Cambridge University Press:  20 November 2021

By
Anastasios Malakasis  and
Francoise H. Harlow
Edited by
Tahir Mahmood ,
Charles Savona Ventura ,
Ioannis Messinis  and
Sambit Mukhopadhyay
Tahir Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Charles Savona Ventura
Affiliation:
University of Malta, Malta
Ioannis Messinis
Affiliation:
University of Thessaly, Greece
Sambit Mukhopadhyay
Affiliation:
Norfolk & Norwich University Hospital, UK
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Summary

Thyroid disease is a common finding in the female population. The prevalence of hypothyroidism is 1–2 per 100 women and the prevalence of hyperthyroidism is between 5 and 20 per 1000 women in iodine-replete communities [1]. These numbers may be higher in areas with iodine insufficiency. Thyroid disease is 10-fold higher in the female population in comparison to the male [1]. Considering the high prevalence in the female population, we understand that thyroid disease is very common in pregnant women, with the overall rate of overt thyroid dysfunction being as high as 1% of all pregnancies [2]. In this chapter, we will review the physiology in pregnancy, the normal adaptations of the thyroid gland and hormones and will mention the challenges in thyroid function tests in pregnancy. Furthermore, we will also concentrate on the impact of hypothyroidism and hyperthyroidism on pregnancy, and the diagnosis and management of both. We will also briefly overview postpartum thyroiditis and thyroid cancer in pregnancy.

Type
Chapter
Information
The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
Obstetrics & Maternal-Fetal Medicine
 , pp. 304 - 310
Publisher: Cambridge University Press
Print publication year: 2021

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