Universities are not only institutions of higher education; they also constitute powerful economic actors not the least as buyers of products and services for their own use and for sale to their customers. A special category of products is the clothes, sportswear, memorabilia and many other goods which carry – often conspicuously – the logo of the university. The chapter narrates the 20-plus year history of the search by the University of Notre Dame for its policy to promote corporate responsibility in the supply chains of Notre Dame trademark-licensed products. With the help of two organizations specializing in supply chain assessment, Notre Dame developed a new policy, which is appropriate – with a high level of confidence – to respect human rights in factories located in countries with and without national legislation of freedom of association and collective bargaining. The chapter concludes with policy suggestions for other universities and outlines several research opportunities for investigating corporate responsibility in supply chains.