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Chapter 4 - Biochemical testing

from Section II - Investigative techniques

Published online by Cambridge University Press:  13 April 2017

Ozgur Mete
Affiliation:
University of Toronto
Sylvia L. Asa
Affiliation:
University of Toronto
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Endocrine Pathology , pp. 87 - 108
Publisher: Cambridge University Press
Print publication year: 2000

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References

Burtis, C, Ashwood, E, Bruns, D. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 4th ed. Philadelphia, PA: WB Saunders, 2005.Google Scholar
Chiappin, S, Antonelli, G, Gatti, R, De Palo, EF. Saliva specimen: A new laboratory tool for diagnostic and basic investigation. Clin Chim Acta 2007;383:3040.CrossRefGoogle ScholarPubMed
Pfaffe, T, Cooper-White, J, Beyerlein, P, Kostner, K, Punyadeera, C. Diagnostic potential of saliva: current state and future applications. Clin Chem 2011;57:675687.Google Scholar
Adeli, K. Closing the gaps in pediatric reference intervals: The CALIPER initiative. Clin Biochem 2011;44:480482.CrossRefGoogle Scholar
Bailey, D, Colantonio, D, Kyriakopoulou, L, et al. Marked biological variance in endocrine and biochemical markers in childhood: Establishment of pediatric reference intervals using healthy community children from the CALIPER cohort. Clin Chem 2013;59:13931405.CrossRefGoogle ScholarPubMed
Jung, B, Adeli, K. Clinical laboratory reference intervals in pediatrics: The CALIPER initiative. Clin Biochem 2009;42:15891595.CrossRefGoogle Scholar
Beckett, G, MacKenzie, F. Thyroid guidelines: are thyroid-stimulating hormone assays fit for purpose? Ann Clin Biochem 2007;44:203208.Google Scholar
Weetman, AP. Thyroid-stimulating hormone assays: guidelines, guidance and clinical judgement. Ann Clin Biochem 2007;44:201202.Google Scholar
Dasgupta, A, Bernard, DW. Herbal remedies: effects on clinical laboratory tests. Arch Pathol Lab Med 2006;130:521528.CrossRefGoogle ScholarPubMed
Kang, GY, Parks, JR, Fileta, B, et al. Thyroxine and triiodothyronine content in commercially available thyroid health supplements. Thyroid 2013;23:12331237.Google Scholar
Ellis, MJ, Livesey, JH, Evans, MJ. Hormone stability in human whole blood. Clin Biochem 2003;36:109112.CrossRefGoogle Scholar
Bowen, RA, Chan, Y, Cohen, J, et al. Effect of blood collection tubes on total triiodothyronine and other laboratory assays. Clin Chem 2005;51:424433.Google Scholar
Booth, G, Zahedi, A, Ezzat, S. Evaluation of normal pituitary function. In Melmed, S ed. The Pituitary, 2nd edn, Appendix. Boston, MA: Blackwell, 2002.Google Scholar
Bossuyt, PM, Reitsma, JB, Bruns, DE, et al. Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD initiative. standards for reporting of diagnostic accuracy. Clin Chem 2003;49:16.CrossRefGoogle ScholarPubMed
Dimeski, G. Interference testing. Clin Biochem Rev 2008;29(suppl 1):S43S48.Google Scholar
Kroll, MH, Elin, RJ. Interference with clinical laboratory analyses. Clin Chem 1994;40:19962005.Google Scholar
Klee, GG. Interferences in hormone immunoassays. Clin Lab Med 2004;24:118.CrossRefGoogle ScholarPubMed
Sturgeon, CM, Viljoen, A. Analytical error and interference in immunoassay: minimizing risk. Ann Clin Biochem 2011;48:418432.CrossRefGoogle ScholarPubMed
Tate, J, Ward, G. Interferences in immunoassay. Clin Biochem Rev 2004;25:105120.Google ScholarPubMed
Ismail, AA. Interference from endogenous antibodies in automated immunoassays: what laboratorians need to know. J Clin Pathol 2009;62:673678.Google Scholar
Jones, AM, Honour, JW. Unusual results from immunoassays and the role of the clinical endocrinologist. Clin Endocrinol (Oxf) 2006;64:234244.CrossRefGoogle ScholarPubMed
Butch, AW. Dilution protocols for detection of hook effects/prozone phenomenon. Clin Chem 2000;46:17191721.Google Scholar
Spencer, C, Fatemi, S. Thyroglobulin antibody (TgAb) methods: strengths, pitfalls and clinical utility for monitoring TgAb-positive patients with differentiated thyroid cancer. Best Pract Res Clin Endocrinol Metab 2013;27:701712.Google Scholar
Faix, JD. Principles and pitfalls of free hormone measurements. Best Pract Res Clin Endocrinol Metab 2013;27:631645.Google Scholar
Diver, MJ for the Clinical Scince Reviews Committee of the Association for Clinical Biochemistry. Analytical and physiological factors affecting the interpretation of serum testosterone concentration in men. Ann Clin Biochem 2006;43:312.Google Scholar
Melmed, S, Casanueva, FF, Hoffman, AR, et al. Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011;96:273288.Google Scholar
Klibanski, A. Clinical practice. prolactinomas. N Engl J Med 2010;362:12191226.Google Scholar
Fahie-Wilson, M, Smith, TP. Determination of prolactin: the macroprolactin problem. Best Pract Res Clin Endocrinol Metab 2013;27:725742.CrossRefGoogle ScholarPubMed
Cook, DM, Ezzat, S, Katznelson, L, et al. AACE medical guidelines for clinical practice for the diagnosis and treatment of acromegaly. Endocr Pract 2004;10:213225.Google Scholar
Bidlingmaier, M, Strasburger, CJ. Growth hormone assays: current methodologies and their limitations. Pituitary 2007;10:115119.CrossRefGoogle ScholarPubMed
Brabant, G, Wallaschofski, H. Normal levels of serum IGF-I: determinants and validity of current reference ranges. Pituitary 2007;10:129133.Google Scholar
Freda, PU. Monitoring of acromegaly: what should be performed when GH and IGF-1 levels are discrepant? Clin Endocrinol (Oxf) 2009;71:166170.Google Scholar
Kwan, AY, Hartman, ML. IGF-I measurements in the diagnosis of adult growth hormone deficiency. Pituitary 2007;10:151157.Google Scholar
Molitch, ME, Clemmons, DR, Malozowski, S, Merriam, GR, Vance, ML for the Endocrine Society. Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011;96:15871609.CrossRefGoogle ScholarPubMed
Hartman, ML, Crowe, BJ, Biller, BM, et al. Which patients do not require a GH stimulation test for the diagnosis of adult GH deficiency? J Clin Endocrinol Metab 2002;87:477485.Google Scholar
Corneli, G, Gasco, V, Prodam, F, Grottoli, S, Aimaretti, G, Ghigo, E. Growth hormone levels in the diagnosis of growth hormone deficiency in adulthood. Pituitary 2007;10:141149.Google Scholar
Popovic, V. Approach to testing growth hormone (GH) secretion in obese subjects. J Clin Endocrinol Metab 2013;98:17891796.Google Scholar
Bonert, V. Diagnostic challenges in acromegaly: a case-based review. Best Pract Res Clin Endocrinol Metab 2009;23(suppl 1):S23S30.CrossRefGoogle ScholarPubMed
Clemmons, DR. Consensus statement on the standardization and evaluation of growth hormone and insulin-like growth factor assays. Clin Chem 2011;57:555559.Google Scholar
Clemmons, DR. IGF-I assays: current assay methodologies and their limitations. Pituitary 2007;10:121128.Google Scholar
Cole, LA, DuToit, S, Higgins, TN. Total hCG tests. Clin Chim Acta 2011;412:22162222.CrossRefGoogle ScholarPubMed
Botelho, JC, Shacklady, C, Cooper, HC, et al. Isotope-dilution liquid chromatography–tandem mass spectrometry candidate reference method for total testosterone in human serum. Clin Chem 2013;59:372380.CrossRefGoogle ScholarPubMed
de Ronde, W, van der Schouw, YT, Pols, HA, et al. Calculation of bioavailable and free testosterone in men: a comparison of 5 published algorithms. Clin Chem 2006;52:17771784.Google Scholar
Morales, A, Collier, CP, Clark, AF. A critical appraisal of accuracy and cost of laboratory methodologies for the diagnosis of hypogonadism: the role of free testosterone assays. Can J Urol 2012;19:63146318.Google Scholar
Sartorius, G, Ly, LP, Sikaris, K, McLachlan, R, Handelsman, DJ. Predictive accuracy and sources of variability in calculated free testosterone estimates. Ann Clin Biochem 2009;46:137143.Google Scholar
Belchetz, PE, Barth, JH, Kaufman, JM. Biochemical endocrinology of the hypogonadal male. Ann Clin Biochem 2010;47:503515.Google Scholar
Rosner, W, Vesper, H, for the Endocrine Society, et al. Toward excellence in testosterone testing: a consensus statement. J Clin Endocrinol Metab 2010;95:45424548.Google Scholar
Rosner, W, Hankinson, SE, Sluss, PM, Vesper, HW, Wierman, ME. Challenges to the measurement of estradiol: an Endocrine Society position statement. J Clin Endocrinol Metab 2013;98:13761387.CrossRefGoogle Scholar
Fenske, W, Allolio, B. Clinical review: current state and future perspectives in the diagnosis of diabetes insipidus. A clinical review. J Clin Endocrinol Metab 2012;97:34263437.Google Scholar
Bahn, RS, Burch, HB, Cooper, DS, et al. Hyperthyroidism and other causes of thyrotoxicosis: management guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists. Endocr Pract 2011;17:456520.Google Scholar
Garber, JR, Cobin, RH, Gharib, H, et al. Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association. Thyroid 2012;22:12001235.CrossRefGoogle Scholar
Persani, L. Clinical review: central hypothyroidism: pathogenic, diagnostic, and therapeutic challenges. J Clin Endocrinol Metab 2012;97:30683078.Google Scholar
Despres, N, Grant, AM. Antibody interference in thyroid assays: a potential for clinical misinformation. Clin Chem 1998;44:440454.Google Scholar
Stagnaro-Green, A, Abalovich, M, Alexander, E, et al. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid 2011;21:10811125.Google Scholar
Sinclair, D. Clinical and laboratory aspects of thyroid autoantibodies. Ann Clin Biochem 2006;43:173183.Google Scholar
Barbesino, G, Tomer, Y. Clinical review: clinical utility of TSH receptor antibodies. J Clin Endocrinol Metab 2013;98:22472255.Google Scholar
Olateju, TO, Vanderpump, MP. Thyroid hormone resistance. Ann Clin Biochem 2006;43:431440.Google Scholar
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, Cooper, DS, Doherty, GM, Haugen, BR, et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 2009;19:11671214.Google Scholar
Hoofnagle, AN, Roth, MY. Clinical review: improving the measurement of serum thyroglobulin with mass spectrometry. J Clin Endocrinol Metab 2013;98:13431352.Google Scholar
Elisei, R, Romei, C. Calcitonin estimation in patients with nodular goiter and its significance for early detection of MTC: European comments to the guidelines of the American Thyroid Association. Thyroid Res 2013;6(suppl 1):S2–6614–6-S1-S2. Epub 2013 Mar 14.Google Scholar
Daumerie, C, Maiter, D, Gruson, D. Serum calcitonin estimation in medullary thyroid cancer: Basal or stimulated levels? Thyroid Res 2013;6(suppl 1):S2.CrossRefGoogle ScholarPubMed
Colombo, C, Verga, U, Mian, C, et al. Comparison of calcium and pentagastrin tests for the diagnosis and follow-up of medullary thyroid cancer. J Clin Endocrinol Metab 2012;97:905913.Google Scholar
Daniels, GH. Screening for medullary thyroid carcinoma with serum calcitonin measurements in patients with thyroid nodules in the United States and Canada. Thyroid 2011;21:11991207.Google Scholar
Giovanella, L, Verburg, FA, Imperiali, M, Valabrega, S, Trimboli, P, Ceriani, L. Comparison of serum calcitonin and procalcitonin in detecting medullary thyroid carcinoma among patients with thyroid nodules. Clin Chem Lab Med 2013;51:14771481.Google Scholar
Funder, JW, Carey, RM, Fardella, C, et al. Case detection, diagnosis, and treatment of patients with primary aldosteronism: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2008;93:32663281.CrossRefGoogle ScholarPubMed
Stowasser, M, Taylor, PJ, Pimenta, E, Ahmed, AH, Gordon, RD. Laboratory investigation of primary aldosteronism. Clin Biochem Rev 2010;31:3956.Google Scholar
Oelkers, W. Adrenal insufficiency. N Engl J Med 1996;335:12061212.Google Scholar
Nieman, LK, Biller, BM, Findling, JW, et al. The diagnosis of Cushing's syndrome: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2008;93:15261540.Google Scholar
Inder, WJ, Dimeski, G, Russell, A. Measurement of salivary cortisol in 2012: laboratory techniques and clinical indications. Clin Endocrinol (Oxf) 2012;77:645651.CrossRefGoogle ScholarPubMed
Raff, H. Utility of salivary cortisol measurements in Cushing's syndrome and adrenal insufficiency. J Clin Endocrinol Metab 2009;94:36473655.Google Scholar
Newell-Price, J, Bertagna, X, Grossman, AB, Nieman, LK. Cushing's syndrome. Lancet 2006;367:16051617.Google Scholar
Merke, DP, Bornstein, SR. Congenital adrenal hyperplasia. Lancet 2005;365:21252136.Google Scholar
Marsden, D, Larson, CA. Emerging role for tandem mass spectrometry in detecting congenital adrenal hyperplasia. Clin Chem 2004;50:467468.Google Scholar
Kushnir, MM, Rockwood, AL, Roberts, WL, et al. Development and performance evaluation of a tandem mass spectrometry assay for 4 adrenal steroids. Clin Chem 2006;52:15591567.Google Scholar
Grouzmann, E, Lamine, F. Determination of catecholamines in plasma and urine. Best Pract Res Clin Endocrinol Metab 2013;27:713723.CrossRefGoogle ScholarPubMed
Ward, BK, Magno, AL, Walsh, JP, Ratajczak, T. The role of the calcium-sensing receptor in human disease. Clin Biochem 2012;45:943953.Google Scholar
D'Amour, P. Circulating PTH molecular forms: what we know and what we don't. Kidney Int Suppl 2006;102:S29S33.Google Scholar
Souberbielle, JC, Friedlander, G, Cormier, C. Practical considerations in PTH testing. Clin Chim Acta 2006;366:8189.CrossRefGoogle ScholarPubMed
Farrell, CJ, Herrmann, M. Determination of vitamin D and its metabolites. Best Pract Res Clin Endocrinol Metab 2013;27:675688.Google Scholar
Fraser, WD. Hyperparathyroidism. Lancet 2009;374:145158.CrossRefGoogle ScholarPubMed
Imel, EA, Econs, MJ. Approach to the hypophosphatemic patient. J Clin Endocrinol Metab 2012;97:696706.Google Scholar
Endres, DB. Investigation of hypercalcemia. Clin Biochem 2012;45:954963.Google Scholar
Thakker, RV, Newey, PJ, Walls, GV, et al. Clinical practice guidelines for multiple endocrine neoplasia type 1 (MEN1). J Clin Endocrinol Metab 2012;97:29903011.Google Scholar
Carneiro-Pla, D. Contemporary and practical uses of intraoperative parathyroid hormone monitoring. Endocr Pract 2011;17(suppl 1):4453.CrossRefGoogle ScholarPubMed
Fritchie, K, Zedek, D, Grenache, DG. The clinical utility of parathyroid hormone-related peptide in the assessment of hypercalcemia. Clin Chim Acta 2009;402:146149.Google Scholar
Glendenning, P, Laffer, LL, Weber, HK, Musk, AA, Vasikaran, SD. Parathyroid hormone is more stable in EDTA plasma than in serum. Clin Chem 2002;48:766767.Google Scholar
de Herder, WW. Biochemistry of neuroendocrine tumours. Best Pract Res Clin Endocrinol Metab 2007;21:3341.Google Scholar
Vinik, AI, Silva, MP, Woltering, EA, Go, VL, Warner, R, Caplin, M. Biochemical testing for neuroendocrine tumors. Pancreas 2009;38:876889.Google Scholar
Vinik, AI, Woltering, EA, Warner, RR, et al. NANETS consensus guidelines for the diagnosis of neuroendocrine tumor. Pancreas 2010;39:713734.CrossRefGoogle ScholarPubMed
O'Toole, D, Grossman, A, Gross, D, et al. ENETS consensus guidelines for the standards of care in neuroendocrine tumors: Biochemical markers. Neuroendocrinology 2009;90:194202.Google Scholar
Korse, CM, Muller, M, Taal, BG. Discontinuation of proton pump inhibitors during assessment of chromogranin A levels in patients with neuroendocrine tumours. Br J Cancer 2011;105:11731175.Google Scholar
Mosli, HH, Dennis, A, Kocha, W, Asher, LJ, Van Uum, SH. Effect of short-term proton pump inhibitor treatment and its discontinuation on chromogranin A in healthy subjects. J Clin Endocrinol Metab 2012;97:E17311735.Google Scholar
Heurtault, B, Reix, N, Meyer, N, et al. Extensive study of human insulin immunoassays: promises and pitfalls for insulin analogue detection and quantification. Clin Chem Lab Med 2014;52:355362.Google Scholar
Neal, JM, Han, W. Insulin immunoassays in the detection of insulin analogues in factitious hypoglycemia. Endocr Pract 2008;14:10061010.Google Scholar

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