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Phosphohistone H3 (pHH3)

from Section 1 - Antibodies

Published online by Cambridge University Press:  27 October 2016

Edited by
Runjan Chetty ,
Kumarasen Cooper  and
Allen M. Gown
Runjan Chetty
Affiliation:
University of Toronto
Kumarasen Cooper
Affiliation:
University of Pennsylvania
Allen M. Gown
Affiliation:
Phenopath Laboratories, Seattle
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Information
Leong's Manual of Diagnostic Antibodies for Immunohistology , pp. 381 - 382
Publisher: Cambridge University Press
Print publication year: 2016

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References

Selected references

Juan, G, Traganos, F, James, WM, et al. Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis. Cytometry 1998; 32: 71–7.3.0.CO;2-H>CrossRefGoogle ScholarPubMed
Ribalta, T, McCutcheon, IE, Aldape, KD, et al. The mitosis-specific antibody anti-phosphohistone-H3 (PHH3) facilitates rapid reliable grading of meningiomas according to WHO 2000 criteria. American Journal of Surgical Pathology 2004; 28: 1532–6.CrossRefGoogle ScholarPubMed
Shibata, K, Ajiro, K. Cell cycle-dependent suppressive effect of histone H1 on mitosis-specific H3 phosphorylation. Journal of Biological Chemistry 1993; 268: 18, 431–4.CrossRefGoogle ScholarPubMed
Tetzlaff, MT, Curry, JL, Ivan, D, et al. Immunodetection of phosphohistone H3 as a surrogate of mitotic figure count and clinical outcome in cutaneous melanoma. Modern Pathology 2013; 26: 1153–60.CrossRefGoogle ScholarPubMed
Voss, SM, Riley, MP, Lokhandwala, PM, Wang, M, Yang, Z. Mitotic count by phosphohistone H3 immunohistochemical staining predicts survival and improves interobserver reproducibility in well-differentiated neuroendocrine tumors of the pancreas. American Journal of Surgical Pathology 2015; 39: 13–24.CrossRefGoogle ScholarPubMed

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