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5 - Pregnancy of Unknown Location

Published online by Cambridge University Press:  20 October 2017

Emma Kirk
Affiliation:
Royal Free Hospital, London
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Summary

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Chapter
Information
Early Pregnancy Ultrasound
A Practical Guide
, pp. 33 - 38
Publisher: Cambridge University Press
Print publication year: 2017

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References

Further Reading

Barnhart, K, van Mello, NM, Bourne, T, Kirk, E, Van Calster, B, Bottomley, C, Chung, K, Condous, G, Goldstein, S, Hajenius, PJ, Mol, BW, Molinaro, T, KL O’Flynn O’Brien, KL, Husicka, R, Sammel, M, Timmerman, D (2011). Pregnancy of unknown location: a consensus statement of nomenclature, definitions, and outcome. Fertil Steril. 95(3): 857866.CrossRefGoogle ScholarPubMed
Kirk, E, Bottomley, C, Bourne, T (2014). Diagnosing ectopic pregnancy and current concepts in the management of pregnancy of unknown location. Hum Reprod Update 20(2): 250261.CrossRefGoogle ScholarPubMed
Condous, G, Timmerman, D, Goldstein, S, Valentin, L, Jurkovic, D, Bourne, T (2006). Pregnancies of unknown location: consensus statement. Ultrasound Obstet Gynecol 28: 121122.CrossRefGoogle ScholarPubMed
Bottomley, C, Van Belle, V, Mukri, F, Kirk, E, Van Huffel, S, Timmerman, D, Bourne, T (2009). The optimal timing of an ultrasound scan to assess the location and viability of an early pregnancy. Hum Reprod 24(8): 18111817.CrossRefGoogle ScholarPubMed
Ellaithy, M, Abdelaziz, A, Hassan, MF (2013). Outcome prediction in pregnancies of unknown location using endometrial thickness measurement: is this of real clinical value? Eur J Obstet Gynecol Reprod Biol. 168(1): 6874.CrossRefGoogle ScholarPubMed
Benson, CB, Doubilet, PM, Peters, HE, Frates, MC (2013). Intrauterine fluid with ectopic pregnancy: a reappraisal. Ultrasound Med 32: 389393.CrossRefGoogle ScholarPubMed
Condous, G, Van Calster, B, Kirk, E, Haider, Z, Timmerman, D, Van Huffel, S, Bourne, T (2007). Clinical information does not improve the performance of mathematical models in predicting the outcome of pregnancies of unknown location. Fertil Steril. 88: 572580.CrossRefGoogle Scholar
Cordina, M, Schramm-Gajraj, K, Ross, JA, Lautman, K, Jurkovic, D (2011). Introduction of a single visit protocol in the management of selected patients with pregnancy of unknown location: a prospective study. BJOG 118(6): 693697.CrossRefGoogle ScholarPubMed
Van Mello, N, Mol, F, Opmeer, BC, Ankum, WM, Barnhart, K, Coomarasamy, A, Mol, BW, van der Veen, F, Hajenius, PJ (2012). Diagnostic value of serum hCG on the outcome of pregnancy of unknown location: a systematic review and meta-analysis. Hum Reprod Update 18: 603617.CrossRefGoogle ScholarPubMed
Condous, G, Kirk, E, Lu, C, Van Huffel, S, Gevaert, O, De Moor, B, De Smet, F, Timmerman, D, Bourne, T (2005). Diagnostic accuracy of varying discriminatory zones for the prediction of ectopic pregnancy in women with a pregnancy of unknown location. Ultrasound Obstet Gynecol 26: 770775.CrossRefGoogle ScholarPubMed
Condous, G, Okaro, E, Khalid, A, Timmerman, D, Lu, C, Zhou, Y, Van Huffel, S, Bourne, T (2004). The use of a new logistic regression model for predicting the outcome of pregnancies of unknown location. Hum Reprod. 19(8): 19001910.CrossRefGoogle ScholarPubMed
Van Calster, B, Abdallah, Y, Guha, S, Kirk, E, Van Hoorde, K, Condous, G, Preisler, J, Hoo, W, Stalder, C, Bottomley, C, Timmerman, D, Bourne, T (2013). Rationalizing the management of pregnancies of unknown location: temporal and external validation of a risk prediction model on 1962 pregnancies. Hum Reprod. 28(3): 609616.CrossRefGoogle ScholarPubMed
Guha, S, Ayim, F, Ludlow, J, Sayasneh, A, Condous, G, Kirk, E, Stalder, C, Timmerman, D, Bourne, T, Van Calster, B (2014). Triaging pregnancies of unknown location: the performance of protocols based on single serum progesterone or repeated serum hCG levels. Hum Reprod. 29(5): 938945.CrossRefGoogle ScholarPubMed
Van Calster, B, Bobdiwala, S, Guha, S, Van Hoorde, K, Al-Memar, M, Harvey, R, Farren, J, Kirk, E, Condous, G, Sur, S, Stalder, C, Timmerman, D, Bourne, T (2016). Managing pregnancy of unknown location based on initial serum progesterone and serial serum hCG: development and validation of a two-step triage protocol. Ultrasound Obstet Gynecol [Epub ahead of print].CrossRefGoogle ScholarPubMed

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