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44 - Medical issues related to the care for HIV-infected children in the home, day care, school, and community

from Part VI - Medical, social, and legal issues

Published online by Cambridge University Press:  03 February 2010

Stephen J. Chanock
Affiliation:
Pediatric Oncology Branch, National Cancer Institute, NIH, BethesdaMD
Steven L. Zeichner
Affiliation:
National Cancer Institute, Bethesda, Maryland
Jennifer S. Read
Affiliation:
National Cancer Institute, Bethesda, Maryland
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Summary

Introduction

Children with HIV infection spend very little time in hospital; they live, learn, grow, and play in different settings in the community. Despite significant advances in the understanding of HIV transmission infection, a number of misconceptions continue, spawning misunderstandings that can harm children with HIV infection. In some circumstances, these misunderstandings have led to fear and the ostracism of children with HIV infection in situations which present no discernible risk to others. A major challenge for those caring for children with HIV infection is to promote an acceptance of HIV-infected children in the community. Healthcare providers bear an important responsibility to adequately educate children, their caretakers and the community at large on the risk of transmission of both HIV and other infections. Recommended practices for reducing the risk for transmission should be implemented in a balanced manner and should neither minimize nor exaggerate the relative risk for transmission. Every effort should be made to promote understanding, confidentiality, and compassion for children with HIV infection [1, 2].

Transmission of HIV

Risk for transmission of HIV is directly related to exposure to contaminated body fluids [1]. Since HIV preferentially replicates in cells expressing CD4+ and its co-receptors, transmission is highly associated with exposure to infected cells bearing the CD4 antigen (e.g. T-lymphocytes and monocytes) [3, 4]. HIV has been isolated from many body fluids (see Table 44.1), but HIV transmission is most commonly associated with exposure to body fluids, such as blood or semen, which are especially rich in lymphocytes and monocytes [1].

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Publisher: Cambridge University Press
Print publication year: 2005

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