Book contents
- Frontmatter
- Contents
- List of contributors
- Preface
- 1 A short history of latent inhibition research
- Current topics in latent inhibition research
- 2 Latent inhibition and extinction: their signature phenomena and the role of prediction error
- 3 Inter-stage context and time as determinants of latent inhibition
- 4 Latent inhibition: acquisition or performance deficit?
- 5 Latent inhibition and learned irrelevance in human contingency learning
- 6 Associative and nonassociative processes in latent inhibition: an elaboration of the Pearce–Hall model
- 7 From latent inhibition to retrospective revaluation: an attentional-associative model
- 8 Latent inhibition and habituation: evaluation of an associative analysis
- 9 Latent inhibition and creativity
- 10 The phylogenetic distribution of latent inhibition
- 11 The genetics of latent inhibition: studies of inbred and mutant mice
- 12 A comparison of mechanisms underlying the CS–US association and the CS–nothing association
- 13 The pharmacology of latent inhibition and its relevance to schizophrenia
- 14 Parahippocampal region–dopaminergic neuron relationships in latent inhibition
- 15 Latent inhibition and other salience modulation effects: same neural substrates?
- 16 What the brain teaches us about latent inhibition (LI): the neural substrates of the expression and prevention of LI
- 17 Latent inhibition in schizophrenia and schizotypy: a review of the empirical literature
- 18 A cautionary note about latent inhibition in schizophrenia: are we ignoring relevant information?
- 19 Latent inhibition as a function of anxiety and stress: implications for schizophrenia
- 20 Nicotinic modulation of attentional deficits in schizophrenia
- 21 Latent inhibition and schizophrenia: the ins and outs of context
- Summary and conclusions
- Index
- References
5 - Latent inhibition and learned irrelevance in human contingency learning
from Current topics in latent inhibition research
Published online by Cambridge University Press: 04 August 2010
Book contents
- Frontmatter
- Contents
- List of contributors
- Preface
- 1 A short history of latent inhibition research
- Current topics in latent inhibition research
- 2 Latent inhibition and extinction: their signature phenomena and the role of prediction error
- 3 Inter-stage context and time as determinants of latent inhibition
- 4 Latent inhibition: acquisition or performance deficit?
- 5 Latent inhibition and learned irrelevance in human contingency learning
- 6 Associative and nonassociative processes in latent inhibition: an elaboration of the Pearce–Hall model
- 7 From latent inhibition to retrospective revaluation: an attentional-associative model
- 8 Latent inhibition and habituation: evaluation of an associative analysis
- 9 Latent inhibition and creativity
- 10 The phylogenetic distribution of latent inhibition
- 11 The genetics of latent inhibition: studies of inbred and mutant mice
- 12 A comparison of mechanisms underlying the CS–US association and the CS–nothing association
- 13 The pharmacology of latent inhibition and its relevance to schizophrenia
- 14 Parahippocampal region–dopaminergic neuron relationships in latent inhibition
- 15 Latent inhibition and other salience modulation effects: same neural substrates?
- 16 What the brain teaches us about latent inhibition (LI): the neural substrates of the expression and prevention of LI
- 17 Latent inhibition in schizophrenia and schizotypy: a review of the empirical literature
- 18 A cautionary note about latent inhibition in schizophrenia: are we ignoring relevant information?
- 19 Latent inhibition as a function of anxiety and stress: implications for schizophrenia
- 20 Nicotinic modulation of attentional deficits in schizophrenia
- 21 Latent inhibition and schizophrenia: the ins and outs of context
- Summary and conclusions
- Index
- References
Summary
Introduction
To say that latent inhibition (LI) is a well-established phenomenon of animal conditioning is a serious understatement. Since its first demonstration 50 years ago, the finding of a retardation in conditioning following nonreinforced preexposure to a stimulus has been reported countless times across species from sheep to snails, and from goats to goldfish.
Given the ubiquity of LI in animal conditioning, and the suggestion that, under some circumstances at least, a common associative mechanism might also underlie human contingency learning (the acquisition of knowledge about the predictive relationship between a cue and an outcome; Dickinson, Shanks, & Evenden,1984), we might expect a search of the contingency learning literature to reveal many demonstrations of LI in humans. The conclusions to be drawn from such a search depend largely on whether an empirical or theoretical approach to LI is taken.
An empirical approach to LI
If we define LI empirically, as the experimental observation of a retardation in the development of conditioned responding to a stimulus resulting from nonreinforced preexposure to that stimulus, then we must conclude that LI has been demonstrated many times in human contingency learning (e.g. De la Casa, Ruiz, & Lubow, 1993b; Ginton, Urca, & Lubow, 1975; Gray, N.S., et al., 2001; Lubow, Ingberg-Sachs, Zalstein-Orda, & Gewirtz, 1992). For example, during Ginton et al.'s preexposure phase, participants were required to report the number of repetitions of a list of nonsense-syllables (a masking task; see below). The to-be-conditioned stimulus (CS), a burst of noise, was interspersed throughout presentation of this list.
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- Latent InhibitionCognition, Neuroscience and Applications to Schizophrenia, pp. 94 - 113Publisher: Cambridge University PressPrint publication year: 2010
References
, & (1980). The judgment of contingency and the nature of the response alternatives. Canadian Journal of Psychology, 34, 1–11.CrossRefGoogle Scholar
, & (1979). Preexposure to the CS alone, or CS and US uncorrelated: latent inhibition, blocking by context or learned irrelevance?Learning and Motivation, 10, 278–294.CrossRefGoogle Scholar
, & (1982). Extinction of the context and latent inhibition. Learning and Motivation, 13, 391–416.CrossRefGoogle Scholar
, , & (1988). Differential performance of acute and chronic schizophrenics in a latent inhibition task. Journal of Nervous and Mental Disease, 176, 598–606.CrossRefGoogle Scholar
, , , & (2000). Is the context specificity of latent inhibition a sufficient explanation of learned irrelevance?Quarterly Journal of Experimental Psychology, 53B, 239–253.CrossRefGoogle Scholar
, , , & (2005). Acquired distinctiveness and equivalence in human discrimination learning: evidence for an attentional process. Psychonomic Bulletin & Review, 12, 88–92.CrossRefGoogle ScholarPubMed
, & (2003). Learned irrelevance: a contemporary overview. Quarterly Journal of Experimental Psychology, 56B, 80–89.CrossRefGoogle Scholar
(1993). Context, time, and memory retrieval in the interference paradigms of Pavlovian learning. Psychological Bulletin, 114, 80–99.CrossRefGoogle ScholarPubMed
, & (1983). Contextual effects in latent inhibition with an appetitive conditioning procedure. Animal Learning & Behavior, 11, 67–74.CrossRefGoogle Scholar
, , & (1993a). Amphetamine-produced attenuation of latent inhibition is modulated by stimulus preexposure duration: implications for schizophrenia. Biological Psychiatry, 33, 707–711.CrossRefGoogle Scholar
, , & (1993b). Latent inhibition and recall/recognition of irrelevant stimuli as a function of preexposure duration in high and low psychotic-prone normal subjects. British Journal of Psychology, 84, 119–132.CrossRefGoogle Scholar
, , & (1984). Judgement of act-outcome contingency: the role of selective attribution. Quarterly Journal of Experimental Psychology, 36A, 29–50.CrossRefGoogle Scholar
, , & (2003). Latent inhibition in human adults without masking. Journal of Experimental Psychology: Learning, Memory, and Cognition, 29, 1028–1040.Google ScholarPubMed
, , & (2007). A new continuous within-participants latent inhibition task: examining associations with schizotypy dimensions, smoking status and gender. Biological Psychology, 74, 365–373.CrossRefGoogle ScholarPubMed
, & (1999). Acquired distinctiveness is controlled by stimulus relevance not correlation with reward. Journal of Experimental Psychology: Animal Behavior Processes, 25, 363–373.Google Scholar
, , & (1975). The effects of preexposure to a nonattended stimulus on subsequent learning: latent inhibition in adults. Bulletin of the Psychonomic Society, 5, 5–8.CrossRefGoogle Scholar
, & (1998). Retardation in human discrimination learning as a consequence of pre-exposure: latent inhibition or negative priming?Quarterly Journal of Experimental Psychology, 51B, 155–172.Google Scholar
, , , , & (2002). What schizotypal dimensions abolish latent inhibition?British Journal of Clinical Psychology, 41, 271–284.CrossRefGoogle ScholarPubMed
, , , , & (1992). Abolition of latent inhibition by a single 5 mg dose of d-amphetamine in man. Psychopharmacology, 107, 425–430.CrossRefGoogle ScholarPubMed
, & (2005). The relevance of irrelevance to schizophrenia. Neuroscience and Biobehavioral Reviews, 29, 989–999.CrossRefGoogle Scholar
, , , et al. (2001). Context dependent latent inhibition in adult humans. Quarterly Journal of Experimental Psychology Section B – Comparative and Physiological Psychology, 54, 233–245.Google ScholarPubMed
(1978). The orienting reaction during human eyelid conditioning following preconditioning exposures to the CS. Psychological Research, 40, 77–88.CrossRefGoogle ScholarPubMed
, & (1987). Hippocampal lesions attenuate latent inhibition and the decline of the orienting response in rats. Quarterly Journal of Experimental Psychology, 39B, 107–125.Google Scholar
, , & (1994). Amphetamine-induced disruptions of latent inhibition are reinforcer mediated: implications for animal models of schizophrenic attentional dysfunction. Psychopharmacology, 115, 185–195.CrossRefGoogle ScholarPubMed
(1996). Dimensional relevance shifts in category learning. Connection Science, 8, 225–247.CrossRefGoogle Scholar
(2001). Towards a unified model of attention in associative learning. Journal of Mathematical Psychology, 45, 812–863.CrossRefGoogle Scholar
, & (2003). Learned associability and associative change in human causal learning. Quarterly Journal of Experimental Psychology, 56B, 68–79.CrossRefGoogle Scholar
, , , et al. (submitted). Stereotype formation: biased by association. Journal of Experimental Psychology: General.
, , , , & (in press). Disentangling the attentional deficit in schizophrenia: pointers from schizotypy. Psychiatry Research.
(1999). The effect of stimulus specificity and number of pre-exposures on latent inhibition in an instrumental trials-to-criterion task. Australian Journal of Psychology, 51, 77–91.CrossRefGoogle Scholar
, , & (2009). Attentional changes during implicit learning: signal validity protects a target stimulus from the attentional blink. Journal of Experimental Psychology: Learning, Memory, and Cognition, 35, 408–422.Google ScholarPubMed
(2003). Causal beliefs and conditioned responses: retrospective revaluation induced by experience and by instruction. Journal of Experimental Psychology: Learning, Memory, and Cognition, 29, 97–106.Google ScholarPubMed
, , & (1984). Context specificity of conditioning and latent inhibition. Journal of Experimental Psychology: Animal Behavior Processes, 10, 360–375.Google Scholar
(1989). Latent Inhibition and Conditioned Attention Theory. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
(2005). Construct validity of the animal latent inhibition model of selective attention deficits in schizophrenia. Schizophrenia Bulletin, 31, 139–153.CrossRefGoogle Scholar
, , & (1982). Latent inhibition and learned helplessness in children: similarities and differences. Journal of Experimental Child Psychology, 34, 231–256.CrossRefGoogle Scholar
, & (1995). Latent inhibition in humans: data, theory, and implications for schizophrenia. Psychological Bulletin, 117, 87–103.CrossRefGoogle Scholar
, , , & (1992). Latent inhibition in low and high psychotic-prone normal subjects. Personality and Individual Differences, 13, 563–572.CrossRefGoogle Scholar
(1973). Stimulus selection: learning to ignore stimuli that predict no change in reinforcement. In & (Eds.), Constraints on Learning. London: Academic Press, pp. 75–96.Google Scholar
(1975). A theory of attention: variations in the associability of stimuli with reinforcement. Psychological Review, 82, 276–298.CrossRefGoogle Scholar
, & (1969). Intradimensional and extradimensional shift learning by pigeons. Psychonomic Science, 14, 5–6.CrossRefGoogle Scholar
, , & (1995). New scales for the assessment of schizotypy. Personality and Individual Differences, 18, 7–13.CrossRefGoogle Scholar
, , & (1988). Learned irrelevance exceeds the sum of CS-preexposure and US-preexposure deficits. Journal of Experimental Psychology: Animal Behavior Processes, 14, 311–319.Google Scholar
, & (1988). The comparator hypothesis: a response rule for the expression of associations. The Psychology of Learning and Motivation, 22, 51–92.CrossRefGoogle Scholar
, & (2006). A context-specific latent inhibition effect in a human conditioned suppression task. Quarterly Journal of Experimental Psychology, 59, 1003–1020.CrossRefGoogle Scholar
, , , et al. (2001). Involvement of the entorhinal cortex in a process of attentional modulation: evidence from a novel variant of an IDS/EDS procedure. Behavioral Neuroscience, 115, 841–849.CrossRefGoogle Scholar
, & (1980). A model for Pavlovian conditioning: variations in the effectiveness of conditioned but not of unconditioned stimuli. Psychological Review, 87, 532–552.CrossRefGoogle Scholar
(1966). Effect of CS manipulation on the conditioned eyelid response: compounding, generalization, in the inter-CS-interval, and preexposure. Psychonomic Science Monographs, 1, 271–286.Google Scholar
(1971). Summation and retardation tests of latent inhibition. Journal of Comparative and Physiological Psychology, 75.CrossRefGoogle ScholarPubMed
, , & (1971). Optional intradimensional and extradimensional shifts in the rat. Journal of Comparative and Physiological Psychology, 77, 470–475.CrossRefGoogle ScholarPubMed
(1969). Generalization of latent inhibition. Journal of Comparative and Physiological Psychology, 69, 157–159.CrossRefGoogle Scholar
, & (1977). Specificity of conditioning mechanisms in the modification of food preferences. In , & (Eds.), Learning Mechanisms in Food Selection. Waco, TX: Baylor University Press.Google Scholar
(1981). SOP: a model of automatic memory processing in animal behaviour. In & (Eds.), Information Processing in Animals: Memory Mechanisms. Hillsdale, NJ: Lawrence Erlbaum, pp. 5–47.Google Scholar
, & (1987). Facilitation of latent inhibition by haloperidol. Psychopharmacology, 91, 248–253.CrossRefGoogle ScholarPubMed
, , & (1988). Disruption of latent inhibition by acute administration of low doses of amphetamine. Pharmacology, Biochemistry, and Behavior, 30, 871–878.CrossRefGoogle ScholarPubMed
, , , et al. (1997). Haloperidol enhances latent inhibition in visual tasks in healthy people. Psychopharmacology, 133, 262–268.CrossRefGoogle ScholarPubMed
, , & (2005). The role of dopamine in conditioning and latent inhibition: what, when, where and how?Neuroscience and Biobehavioral Reviews, 29, 963–976.CrossRefGoogle Scholar
, & (1995). Context control of negative transfer induced by preexposure to irrelevant stimuli: latent inhibition in humans. Learning and Motivation, 26, 11–28.CrossRefGoogle Scholar
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