Skip to main content Accessibility help
×
Hostname: page-component-848d4c4894-x5gtn Total loading time: 0 Render date: 2024-06-02T04:28:08.491Z Has data issue: false hasContentIssue false

7 - Fertility-preserving surgery in women with cancer of the cervix

from SECTION 2 - Fertility Issues and Paediatric Cancers

Published online by Cambridge University Press:  05 October 2014

John Shepherd
Affiliation:
The Royal Marsden Hospital
Sean Kehoe
Affiliation:
John Radcliffe Hospital, Oxford
Eric Jauniaux
Affiliation:
University College Hospital, London
Pierre Martin-Hirsch
Affiliation:
Royal Preston Hospital
Philip Savage
Affiliation:
Charing Cross Hospital, London
Get access

Summary

Introduction

While cervical cancer remains the second most common female tumour with over 500 000 cases per year, the incidence has fallen dramatically in countries that have introduced successful screening programmes, predominantly in the western world. As a result, in those countries there has been a disproportionate rise in the incidence of cervical precancer or intraepithelial neoplasia as well as early-stage disease, especially of glandular tumours. There has thus been an increase in demand for fertility-sparing techniques to be developed.

Standard treatment for cervical cancer has until recently been either radical hysterectomy or radiotherapy to the pelvis. Both will result in future childbearing being impossible. A radical wide local excision of carefully selected early-stage tumours will allow conservation of the body of the uterus with a vaginoisthmic anastomosis enabling continuity of the vagina to be preserved following insertion of an isthmic cerclage suture. Pelvic node dissection may be performed at the same time by laparoscopic techniques.

Over 900 cases have been performed and reported in the worldwide literature. Most have been carried out vaginally (radical vaginal trachelectomy and laparoscopic pelvic node dissection). A smaller number have been performed abdominally. There have been over 300 pregnancies reported, with 196 live births. This technique is suitable in well-selected cases in young women with small tumours who are well motivated to preserve their fertility potential.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×