In the course of the residencia of the Second Audiencia of Mexico, Licenciado Vasco de Quiroga was charged with having overburdened the Indians of Mexico City with the work of constructing his hospital-town of Santa Fe near the city. The official charge (cargo XXVI), as formulated by Francisco de Loaysa, judge of residencia, has been published twice, together with some of the questions that Quiroga drew up for his witnesses in answer to the charge, the answers of the witnesses, and the final decision of the judge, which absolved Quiroga of any guilt in the matter. But the source of the charge, as well as Quiroga’s personal reply to it, have remained unpublished.