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DEPRESSIONAMONG PATIENTS WHO SURVIVED COVID 19 INTHE EMERGENCY DEPARTMENT
- K. Hamrouni, R. Youssef, K. Hlimi, A. Loghmari, W. Houas, H. Yaacoubi, L. Boukadida, H. Ben Salah, M. Ben othmen, I. Khalifa, R. Jaballah, A. Zorgati, R. Boukef
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- Journal:
- European Psychiatry / Volume 66 / Issue S1 / March 2023
- Published online by Cambridge University Press:
- 19 July 2023, p. S776
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- Article
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Introduction
The current SARS cov 2 virus disease pandemic presents a threatening physical danger as well as its impact on mental health. It seems important to screen any patient who has experienced covid 19 for its psychological impact.
ObjectivesTherefore the aim of our study was to highlight the impact of COVID-19 infection on mental health by screening them for depression
MethodsThis is a cross-sectional, single-center study, conducted at the Sahloul Emergency Department, over a period of 5 months (January to May 2021). Patients are collected from a database of ouremergencydepartment COVID-19 unit.We included patients whose age is greater than or equal to 18 years old; who has been infected with SARS-COV-2 according to the results of the PCR test. All patients lost to follow-up, refusing to participate in this study, having a psychiatric illness or having taken a psychotropic medication before randomization or non-cooperating (unable to respond to the evaluation test) were excluded.A telephone follow-up was done after 30 days from admission to calculate the HAMILTON score after a positif HAD D scale.
Results200 patients were included. For the 20 patients (10%) with depressive symptomatology (doubtful and certain) according to the HAD D scale, their responses to the Hamilton scale were analysed in order to determine the severity of the depressive symptomatology. Note that 30% of patients had mild to moderate signs of depression and 70% had severe depression.The majority of patients in whom the presence of depressive symptoms was noted had an average age of 40 years; those who presented with severe depression had an average age of 51.3 years with a female majority of 72%. No difference was noted in relation to pathological history, half had been hospitalized for treatment of COVID-19(57%). Patients with severe depression symptom resolution lasted an average of 14 days.
ConclusionsAccording to the results of this study, interventions may be carried out to minimize the pandemic’s negative psychological consequences.
Disclosure of InterestNone Declared
Is lithium implicated in tobacco addiction?
- I. Houas, D. Haj Mouhamed, G. Gallelo, W. Douki, L. Gaha, M.L. Cervera, M. De la Guardia
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- Journal:
- European Psychiatry / Volume 33 / Issue S1 / March 2016
- Published online by Cambridge University Press:
- 23 March 2020, p. S116
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Introduction
Tobacco is a source of mineral elements that can affect human health in various ways, such as lithium, which is used as a psychiatric medication. Lithium salts are used as mood-stabilizing drugs and indicated in the treatment of manic-depressive psychosis.
ObjectiveStudying the lithium content in tobacco over the smokers’plasma content and evaluate the potential role of lithium in tobacco addiction.
MethodsA total of 18 different tobacco products (cigarettes, smokeless and water pipe tobacco) and 125 plasma samples (45 from smokers, 10 from ex-smokers and 70 from non-smokers) were collected to determinate the lithium content. Tobacco samples were digested with nitric acid and lithium concentration was measured by inductively coupled plasma-optical emission. The collected plasma samples were diluted 1/10 with a nitric acid solution and the lithium level was measured by inductively coupled plasma-mass spectrometry.
ResultsThe average concentration of lithium in the cigarettes (16.59 ± 0.59 μg/g) was higher compared to those in the smokeless tobacco (8.39 ± 4.44 μg/g) and in the water pipe tobacco (6.13 ± 6.32 μg/g) but with no significant difference (P = 0.182). For plasma lithium levels, there was no significant difference (P = 0.186) between smokers and non-smokers (6.20 ± 6.24 vs. 4.98 ± 6.20 μg/g). However, a significant negative correlation was noted between plasma and the lithium content in tobacco products (r = –0.435; P = 0.04). The lithium plasma level was significantly and negatively correlated with the dependence score (r = –0.316; P = 0.031).
ConclusionThe correlation between plasmatic lithium and dependence score in smokers suggests that lithium would be involved in tobacco addiction probably through his regulating action of mood.
Disclosure of interestThe authors have not supplied their declaration of competing interest.