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Clinico-pathological profile evaluation in patients affected by chronic inflammatory bowel diseases
- F. Travagliati, E. Borrelli, S. Martinelli, L. Dattoli, D. Ferrarese, E. Gaetani, F. Scaldaferri, A. Gasbarrini, L. Janiri, G. Camardese
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- Journal:
- European Psychiatry / Volume 41 / Issue S1 / April 2017
- Published online by Cambridge University Press:
- 23 March 2020, p. S320
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Introduction
Inflammatory bowel diseases (IBDs) have high social impact. Aetiology is still unknown, however multifactorial genesis is surely implicated. We tried to correlate IBDs and psychological distress through evaluated psychometrical instruments and subsequently to relate subjective influences with gastroenteric clinical manifestation, defining new critical elements on which IBD are based.
MethodsIn our study, we included 57 participants, selected according to their diagnosis, between those attending our gastrointestinal ambulatory: 26 had Chron's disease, while 31 had ulcerative colitis. 78 people without gastroenteric or psychiatric disorder were also included in the study as control group. Psychometric questionnaires were administered to evaluate anxiety and depressive symptoms, quality of live, self-efficacy and resilience (Fig. 1).
ResultsLevels of anxiety and depression were higher in patients with IBDs than in the control group. STAI-Y highlighted higher state anxiety and trait anxiety levels in first group. HADS showed higher scores in ill patients, as well as CD-RISC showed a more impaired resilience. EQ-VAS, PGWBI and GSE revealed significant differences in health status, psychological wellness and self-efficacy between the two groups.
ConclusionsIBDs seem related to psychological diseases. Affected patients have higher anxiety and depression levels than general population as well as lower self-efficacy and resilience. Those elements being strictly linked to physical discomfort contributes to develop a loop in which patients get caught. Creating a model of integrated cooperation between gastroenterologist and psychiatrist during treatment of patients with IBDs seems fundamental to grant at once all the professional figures each patient needs for better care.
Disclosure of interestThe authors have not supplied their declaration of competing interest.
The SPARC/X SASE-FEL Projects
- D. ALESINI, S. BERTOLUCCI, M.E. BIAGINI, R. BONI, M. BOSCOLO, M. CASTELLANO, A. CLOZZA, G.. DI PIRRO, A. DRAGO, A. ESPOSITO, M. FERRARIO, V. FUSCO, A. GALLO, A. GHIGO, S. GUIDUCCI, M. INCURVATI, C. LIGI, F. MARCELLINI, M. MIGLIORATI, C. MILARDI, A. MOSTACCI, L. PALUMBO, L. PELLEGRINO, M. PREGER, P. RAIMONDI, R. RICCI, C. SANELLI, M. SERIO, F. SGAMMA, B. SPATARO, A. STECCHI, A. STELLA, F. TAZZIOLI, C. VACCAREZZA, M. VESCOVI, C. VICARIO, M. ZOBOV, F. ALESSANDRIA, A. BACCI, I. BOSCOLO, F. BROGGI, S. CIALDI, C. DE MARTINIS, D. GIOVE, C. MAROLI, V. PETRILLO, M. ROMÈ, L. SERAFINI, P. MUSUMECI, M. MATTIOLI, L. CATANI, E. CHIADRONI, S. TAZZARI, F. CIOCCI, G. DATTOLI, A. DORIA, F. FLORA, G.P. GALLERANO, L. GIANNESSI, E. GIOVENALE, G. MESSINA, L. MEZI, P.L. OTTAVIANI, L. PICARDI, M. QUATTROMINI, A. RENIERI, C. RONSIVALLE, A. CIANCHI, C. SCHAERF, J.B. ROSENZWEIG
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- Journal:
- Laser and Particle Beams / Volume 22 / Issue 3 / July 2004
- Published online by Cambridge University Press:
- 01 July 2004, pp. 341-350
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SPARC and SPARX are two different initiatives toward an Italian Free Electron Laser (FEL) source operating in the Self Amplified Spontaneous Emission (SASE) mode, in which several national research institutions are involved. SPARC is a high gain FEL project devoted to provide a source of visible and VUV radiation while exploiting the SASE mechanism. An advanced Photo-Injector system, emittance compensating RF-gun plus a 150 MeV Linac, will inject a high quality e-beam into the undulator to generate high brilliance FEL radiation in the visible region at the fundamental wavelength, (∼500 nm). The production of flat top drive laser beams, high peak current bunches, and emittance compensation scheme will be investigated together with the generation of higher harmonic radiation in the VUV region. SPARX is the direct evolution of such a high gain SASE FEL toward the 13.5 and 1.5 nm operating wavelengths, at 2.5 GeV. To get the required value for the bunch peak current, Ipeak ≈ 2.5 kA, the “hybrid” scheme, RF-compression stage plus magnetic chicane, is analyzed and compared with the more standard double stage of magnetic compression. The two options are reviewed considering the tolerance to the drive laser pulse phase jitter.
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