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Advocacy at the Eighth World Congress of Pediatric Cardiology and Cardiac Surgery
- Bistra Zheleva, Amy Verstappen, David M. Overman, Farhan Ahmad, Sulafa K.M. Ali, Zohair Y. Al Halees, Joumana Ghandour Atallah, Isabella E. Badhwar, Carissa Baker-Smith, Maria Balestrini, Amy Basken, Jonah S. Bassuk, Lee Benson, Horacio Capelli, Santo Carollo, Devyani Chowdhury, M. Sertaç Çiçek, Mitchell I. Cohen, David S. Cooper, John E. Deanfield, Joseph Dearani, Blanca del Valle, Kathryn M. Dodds, Junbao Du, Frank Edwin, Ekanem Ekure, Nurun Nahar Fatema, Anu Gomanju, Babar Hasan, Lewis Henry, Christopher Hugo-Hamman, Krishna S. Iyer, Marcelo B. Jatene, Kathy J. Jenkins, Tara Karamlou, Tom R. Karl, James K. Kirklin, Christián Kreutzer, Raman Krishna Kumar, Keila N. Lopez, Alexis Palacios Macedo, Bradley S. Marino, Eva M. Marwali, Folkert J. Meijboom, Sandra S. Mattos, Hani Najm, Dan Newlin, William M. Novick, Sir Shakeel A. Qureshi, Budi Rahmat, Robert Raylman, Irfan Levent Saltik, Craig Sable, Nestor Sandoval, Anita Saxena, Emma Scanlan, Gary F. Sholler, Jodi Smith, James D. St Louis, Christo I. Tchervenkov, Koh Ghee Tiong, Vladimiro Vida, Susan Vosloo, Douglas J. “DJ” Weinstein, James L. Wilkinson, Liesl Zuhlke, Jeffrey P. Jacobs
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- Journal:
- Cardiology in the Young / Volume 33 / Issue 8 / August 2023
- Published online by Cambridge University Press:
- 24 August 2023, pp. 1277-1287
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- Article
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The Eighth World Congress of Pediatric Cardiology and Cardiac Surgery (WCPCCS) will be held in Washington DC, USA, from Saturday, 26 August, 2023 to Friday, 1 September, 2023, inclusive. The Eighth World Congress of Pediatric Cardiology and Cardiac Surgery will be the largest and most comprehensive scientific meeting dedicated to paediatric and congenital cardiac care ever held. At the time of the writing of this manuscript, The Eighth World Congress of Pediatric Cardiology and Cardiac Surgery has 5,037 registered attendees (and rising) from 117 countries, a truly diverse and international faculty of over 925 individuals from 89 countries, over 2,000 individual abstracts and poster presenters from 101 countries, and a Best Abstract Competition featuring 153 oral abstracts from 34 countries. For information about the Eighth World Congress of Pediatric Cardiology and Cardiac Surgery, please visit the following website: [www.WCPCCS2023.org]. The purpose of this manuscript is to review the activities related to global health and advocacy that will occur at the Eighth World Congress of Pediatric Cardiology and Cardiac Surgery.
Acknowledging the need for urgent change, we wanted to take the opportunity to bring a common voice to the global community and issue the Washington DC WCPCCS Call to Action on Addressing the Global Burden of Pediatric and Congenital Heart Diseases. A copy of this Washington DC WCPCCS Call to Action is provided in the Appendix of this manuscript. This Washington DC WCPCCS Call to Action is an initiative aimed at increasing awareness of the global burden, promoting the development of sustainable care systems, and improving access to high quality and equitable healthcare for children with heart disease as well as adults with congenital heart disease worldwide.
11 - Neuropathology of dementia
- Edited by Bruce L. Miller, University of California, San Francisco, Bradley F. Boeve, Mayo Foundation, Minnesota
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- Book:
- The Behavioral Neurology of Dementia
- Published online:
- 31 July 2009
- Print publication:
- 28 May 2009, pp 142-160
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Summary
Introduction
Age-related neurodegenerative diseases represent an increasing public health crisis. In the USA, individuals 85 years of age or older are the fastest growing segment of society, projected to exceed 10 million citizens before 2050. The risk of developing Alzheimer's disease (AD) doubles every five years after age 65, suggesting that the prevalence of dementia will escalate dramatically in the next 40 years.
Major advances in neuroimaging, genetics, molecular biology and neuropathology have begun to refine our understanding of the dementias, providing hope for new therapies. Structural and functional imaging studies now map dementia-related regional and network-level dysfunction in unprecedented detail, and transgenic animals provide testable disease models, bringing new insights into dementia pathogenesis. Genetic studies have identified numerous disease-causing mutations and provide a foothold for understanding the molecular pathology of dementia. Conversely, careful separation of patients with dementia into pathologically homogeneous groupings has accelerated the search for new causative mutations. Accurate prediction of pathology will become even more critical when molecule-specific treatments emerge.
With new discoveries and shifts in opinion, diagnostic frameworks for dementia have evolved rapidly. Formal clinical and pathological diagnostic research criteria for the dementias continue to be revised, with the goal of optimizing clinical–pathological correlations. However, even among patients seen at dementia referral centers, clinical and pathological diagnoses remain discordant in a significant minority of patients. Necessarily, neuropathology remains the gold standard for dementia diagnosis.