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Midlife moderation-quantified healthy diet and 40-year mortality risk from CHD: the prospective National Heart, Lung, and Blood Institute Twin Study − ERRATUM
- Jun Dai, Ruth E. Krasnow, T. Reed
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- Journal:
- British Journal of Nutrition / Volume 121 / Issue 6 / 28 March 2019
- Published online by Cambridge University Press:
- 19 February 2019, pp. 719-720
- Print publication:
- 28 March 2019
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Midlife moderation-quantified healthy diet and 40-year mortality risk from CHD: the prospective National Heart, Lung, and Blood Institute Twin Study
- Jun Dai, Ruth E. Krasnow, Terry Reed
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- Journal:
- British Journal of Nutrition / Volume 116 / Issue 2 / 28 July 2016
- Published online by Cambridge University Press:
- 18 May 2016, pp. 326-334
- Print publication:
- 28 July 2016
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It is unknown whether influences of midlife whole diet on the long-term CHD mortality risk are independent of genetic and common environmental factors or familial predisposition. We addressed this question prospectively using data from the National Heart, Lung, and Blood Institute Twin Study. We included 910 male twins who were middle-aged and had usual diet assessed with nutritionist-administered, cross-checked dietary history interview at baseline (1969–1973). Moderation-quantified healthy diet (MQHD), a dietary pattern, was created to evaluate a whole diet. Primary outcome was time-to-CHD death. Hazard ratios (HR) were estimated using frailty survival model. Known CHD risk factors were controlled. During the follow-up of 40 years through 31 December 2009, 113 CHD deaths, 198 total cardiovascular deaths and 610 all-cause deaths occurred. In the entire cohort, the multivariable-adjusted HR for the overall association (equivalent to a general population association) was 0·76 (95 % CI 0·66, 0·88) per 10-unit increment in the MQHD score for CHD, and the multivariable-adjusted HR for a twin with a MQHD score ten units higher than his co-twin brother was 0·79 (95 % CI 0·64, 0·96, P=0·02) for CHD independent of familial predisposition. Similar results were found for a slightly more food-specified alternative moderation-quantified healthy diet (aMQHD). The between-pair association (reflecting familial influence) was significant for CHD for both MQHD and aMQHD. It is concluded that associations of MQHD and aMQHD with a lower long-term CHD mortality risk are both nutritionally and familially affected, supporting their use for dietary planning to prevent CHD mortality.
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- Edited by Robert Audi, University of Notre Dame, Indiana
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- Book:
- The Cambridge Dictionary of Philosophy
- Published online:
- 05 August 2015
- Print publication:
- 27 April 2015, pp ix-xxx
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Who is a visually impaired child? A model is needed to address this question for children with cerebral visual impairment
- Gordon N Dutton, Ruth E Day, Daphne L McCulloch
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- Journal:
- Developmental Medicine and Child Neurology / Volume 41 / Issue 3 / March 1999
- Published online by Cambridge University Press:
- 01 March 1999, pp. 212-213
- Print publication:
- March 1999
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