This paper presents a review of recent research conducted at the Air Force Wright Aeronautical Laboratories (AFWAL)/Materials Laboratory to develop iron-aluminides as elevated temperature structural materials. The research consisted of investigations on the microstructure, tensile behavior, deformation, and fracture mechanisms of the DO3 and B2 ironaluminides. Binary Fe-Al alloys with a wide range of Al contents, solidsolution ternary alloys and precipitation- and dispersion-strengthened two-phase alloys have been investigated. It is shown that iron-aluminides have a potential to be structural materials at least up to 650°C.