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Knowledge of iron-containing foods among pregnant women in Lagos, Nigeria
- Temitope Elizabeth Adeboye, Akinkunmi Paul Okekunle
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- Journal:
- Proceedings of the Nutrition Society / Volume 79 / Issue OCE2 / 2020
- Published online by Cambridge University Press:
- 10 June 2020, E231
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Abstract Introduction
Anaemia in pregnancy is a global public health problem and about half of all anaemia cases among pregnant women in developing countries are attributable to iron (Fe) deficiency. Perhaps, nutritional knowledge on the vitality of Fe-containing foods among pregnant women is lacking. In the light of the perpetually high burden of anaemia in pregnancy in Nigeria, we conducted a study to assess the knowledge of Fe-containing foods among pregnant women in Lagos, Nigeria.
Materials and MethodsFour hundred and thirty two (432) pregnant women in the 2nd and 3rd trimester of pregnancy (across eight Primary Health Centers in a local government area) from Lagos Nigeria identified through multi-stage sampling method completed validated semi-structured questionnaires on socio-demographic characteristic and knowledge of Fe-containing foods using a validated 10-question knowledge scale (designed by nutrition experts) measured on a 2-point scale. Knowledge score (KS) was categories as poor (2 test was used to evaluate the association between age groups, education, marital status and knowledge of Fe-containing foods (at P < 0.05).
ResultsMean age of all respondents was 28.5 ± 4.6years and 43.3% were below 28years. Mean gestational age was 31.3 ± 4.1weeks, 6.5% and 1.9% reported having a primary formal education only and never married respectively. Mean knowledge score of all respondents was 6.7 ± 2.2 and 34.7% had poor KS about Fe-containing foods. While age of respondents was insignificantly associated with KS, proportion of pregnant women who had good KS was significantly higher (χ2 = 6.6, P = 0.01) among those with at least a college education (66.8%) compared to their counterpart having at a primary formal education only (42.9%). In addition, proportion of respondents with poor KS was significantly lower (χ2 = 9.9, P = 0.007) among those ever married (34.8%) compared to respondents who never married (75.0%).
ConclusionAside nutrition education, the vitality of adequate formal education for women prior to pregnancy and care giving roles cannot be undermined in advancing the knowledge of women on anemia and alleviating the burden anaemia in pregnancy in developing countries.
Is Histidine promising in alleviating the risk of Metabolic disorder?
- Akinkunmi Paul Okekunle, Temitope Elizabeth Adeboye, Rennan Feng
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- Journal:
- Proceedings of the Nutrition Society / Volume 79 / Issue OCE2 / 2020
- Published online by Cambridge University Press:
- 10 June 2020, E413
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Introduction
In recent times, evidence from published reports; randomized clinical trial (RCT), human case-controls, metabolomics, animal and cell studies is gaining rapt significance on the ameliorative potential of histidine (His) in obesity/insulin resistance (IR)/ inflammation outcomes. This study aimed at systematically mining evidence from previously published studies on the vitality of His on metabolic disorder outcomes.
MethodsUsing the MOOSE guidelines we searched PubMed and Cochrane library using the search words “histidine” and “obesity” or “diabetes” or “metabolic syndrome” and included articles on His intake/administration and obesity/diabetes/metabolic disorders involving human and/or animal experimentation.
ResultsWe found low circulating His profile has been associated with metabolic disorders independent of ethnicity [1–4]. Similarly, two separate animal trials [5–6] found His to be significantly lower in diabetic Balb/cA mice and lean Zucker rat. Also, the endogenous absence of His disrupts mitochondrial membrane integrity thereby impairing energy production [7]. In addition, epidemiological report revealed higher dietary His was associated with lower overweight and obesity risk [8]. Though epidemiological reports from the diverse population to assert this observation are insufficient, reports from animal models [9–10] revealed similar conclusions. Also, some reports [11–12] have demonstrated the dose-dependent inhibitory effect of His on some inflammatory markers by assuaging the palmitic acid induced pAkt/Akt expression [12]. Also, His inhibits the up-production of free radicals to impede the extracellular signal-regulated kinase in neurons [13].
ConclusionThese evidences are novel but primarily limited to mostly obesity. In our opinion, future multi-ethnic longitudinal cohort and trials should consider exploring effects of His on non-fatty alcoholic liver diseases and cardiovascular complications. His might as well be beneficial potentially offering significant hope and non-invasive alternatives in the management of metabolic disorders.
Note:Complete citations available inMEDLINE;
[1] PMID: 20834187 [2] PMID: 22266733 [3] PMID: 21996294 [4] PMID: 23697717 [5] PMID:15878720 [6] PMID:15389298 [7] PMID: 4621606 [8] PMID: 27409634 [9] PMID: 17372311 [10] PMID: 15561489 [11] PMID: 16107255 [12] PMID: 23361591 [13] PMID: 22101981