From time to time one meets with the opinion, or with expressions and general phrases indicating the unavowed opinion, that “idiopathic” epilepsy results from a toxæmic state,—that is to say, that epilepsy the disease is caused by poisons circulating in the blood; or less positively that epilepsy the paroxysm is determined, the attack precipitated, by the transient presence in the blood of such poisons; and in both cases the unexpressed idea seems to be that these poisons get there, in the manner of other auto-intoxicants, by reason of the inefficient performance of the digestive function in some respect.