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Behavioural activation by non-specialists appears effective in the treatment of depression. We examined incremental cost-effectiveness of behavioural activation (n = 24) v. treatment as usual (n = 23) in a randomised controlled trial. Intention-to-treat analyses indicated a quality-adjusted life-year (QALY) difference in favour of behavioural activation of 0.20 (95% CI 0.01–0.39, P = 0.042), incremental cost-effectiveness ratio of £5756 per QALY and a 97% probability that behavioural activation is more cost-effective at a threshold value of £20 000. Results are promising for dissemination of behavioural activation but require replication in a larger study.
Behavioural activation appears as effective as cognitive– behaviour therapy (CBT) in the treatment of depression. If equally effective, then behavioural activation may be the preferred treatment option because it may be suitable for delivery by therapists with less training. This is the first randomised controlled trial to look at this possibility.
Aims
To examine whether generic mental health workers can deliver effective behavioural activation as a step-three high-intensity intervention.
Method
A randomised controlled trial (ISRCTN27045243) comparing behavioural activation (n = 24) with treatment as usual (n = 23) in primary care.
Results
Intention-to-treat analyses indicated a difference in favour of behavioural activation of –15.79 (95% CI –24.55 to –7.02) on the Beck Depression Inventory–II and Work and Social Adjustment Scale (mean difference –11.12, 95% CI –17.53 to –4.70).
Conclusions
Effective behavioural activation appears suitable for delivery by generic mental health professionals without previous experience as therapists. Large-scale trial comparisons with an active comparator (CBT) are needed.
We present the case of a 31-year-old man with comorbid schizophrenia and obsessive compulsive disorder (OCD) distinct from delusional beliefs. The OCD was successfully treated to 6-month follow-up with Exposure and Response Prevention (ERP) without leading to significant deterioration of psychotic phenomena. Considerations for clinicians are discussed.
We describe a new search for intrinsically short (μs) dispersed pulses at 21 cm. This search uses coherent de-dispersion, implemented in a distributed computing framework. It will have a sensitivity of 10−18 W/m2 and cover the Arecibo sky ∼ 3 times.
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