A highly accurate multi-point pressure measurement system based on MEMS pressure sensors spliced into a fiber optic cable and suitable for downhole deployment in a CO2 sequestration well was designed, developed and tested in the laboratory. An interrogator system based on a pulsed laser excitation was shown to be capable of multiple (potentially 60+) point sensor measurements on a single fiber. The interrogator was interfaced with the GE PredixTM industrial internet to demonstrate a remote monitoring system. Sensor packages were fabricated and tested at high temperatures and pressures in supercritical CO2. Environmental and stress testing of the sensor components and package indicated areas in which the design of the package should be further improved.