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Diversity and distribution of Blastocystis sp. subtypes in non-human primates

Published online by Cambridge University Press:  08 April 2013

MOHAMMED A. ALFELLANI ,
ALISON S. JACOB ,
NATALI ORTIZ PEREA ,
ROSINA C. KRECEK ,
DERYA TANER-MULLA ,
JACO J. VERWEIJ ,
BRUNO LEVECKE ,
EGBERT TANNICH ,
C. GRAHAM CLARK  and
C. RUNE STENSVOLD
MOHAMMED A. ALFELLANI
Affiliation:
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK Department of Parasitology, Faculty of Medicine, Sebha University, Sebha, Libya
ALISON S. JACOB
Affiliation:
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
NATALI ORTIZ PEREA
Affiliation:
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
ROSINA C. KRECEK
Affiliation:
Department of Research, Ross University School of Veterinary Medicine (RUSVM), Basseterre, St. Kitts Department of Zoology, University of Johannesburg, Auckland Park, South Africa
DERYA TANER-MULLA
Affiliation:
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
JACO J. VERWEIJ
Affiliation:
Department of Parasitology, Leiden University Medical Centre, the Netherlands
BRUNO LEVECKE
Affiliation:
Laboratory for Parasitology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium Centre for Research and Conservation, Royal Zoological Society of Antwerp, Antwerp, Belgium
EGBERT TANNICH
Affiliation:
Bernhard-Nocht-Institut für Tropenmedizin, Hamburg, Germany
C. GRAHAM CLARK
Affiliation:
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
C. RUNE STENSVOLD*
Affiliation:
Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark
*
*Corresponding author: Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Artillerivej 5, DK-2300 Copenhagen S, Denmark. E-mail: run@ssi.dk
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Summary

Blastocystis SSU-rDNA sequence data from 317 captive and free-living non-human primates (NHPs) representing 30 genera of apes, Old and New World (OW and NW) monkeys and prosimians were analysed to investigate subtype (ST) and allele distribution among hosts. Excluding 20 mixed ST infections, 27% of the sequences belonged to ST1, 22% to ST2, 34% to ST3, 1% to ST4, 4% to ST5, 11% to ST8, <1% to ST13 and 1% to ST15. The study confirmed cryptic host specificity of ST1 and ST3; conversely, considerable overlap in ST2 alleles exists among humans and NHPs. Subtype distribution in humans and NHPs differs mainly in that ST4 is rarely reported in NHPs while ST5 and ST8 are both unusual in humans. This may be due to host specificity and/or the apparent geographically restricted range of some subtypes. While the distribution of ST1, ST2 and ST3 was independent of NHP group or geographical association, ST5 was seen only in apes and OW monkeys and ST8 primarily in arboreal NHPs and only in species native to Asia or South America.

Keywords

Blastocystisnon-human primateshost rangegenetic diversity
Type
Research Article
Information
Parasitology , Volume 140 , Issue 8 , July 2013 , pp. 966 - 971
Copyright
Copyright © Cambridge University Press 2013 

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